FR2394527A1 - N- (3'-PHENYLTHIOPROPYL) -3,3-DIPHENYLPROPYLAMINES SUBSTITUTED WITH PHARMACOLOGICAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents
N- (3'-PHENYLTHIOPROPYL) -3,3-DIPHENYLPROPYLAMINES SUBSTITUTED WITH PHARMACOLOGICAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEMInfo
- Publication number
- FR2394527A1 FR2394527A1 FR7817593A FR7817593A FR2394527A1 FR 2394527 A1 FR2394527 A1 FR 2394527A1 FR 7817593 A FR7817593 A FR 7817593A FR 7817593 A FR7817593 A FR 7817593A FR 2394527 A1 FR2394527 A1 FR 2394527A1
- Authority
- FR
- France
- Prior art keywords
- diphenylpropylamines
- phenylthiopropyl
- substituted
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000000144 pharmacologic effect Effects 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 239000000812 cholinergic antagonist Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002921 anti-spasmodic effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Ces produits sont ceux de la formule (1) dans laquelle R représente un hydrogène ou un groupe alcoyle contenant à à 4 atomes de carbone; R', R'', R''' et R'''', semblables ou différents les uns des autres, représentent des atomes d'hydrogène ou des groupes OH, avec cette limitation que quand R', R'', R''' et R'''' sont tous des atomes d'hydrogène, R ne peut pas être un atome d'hydrogène, et leurs sels avec des acides organiques et inorganiques acceptables pharmaceutiquement. Application : médicaments utilisables comme drogues antiulcéreuses, antispasmodiques et/ou spasmolytiques.These products are those of formula (1) in which R represents a hydrogen or an alkyl group containing from 4 to 4 carbon atoms; R ', R' ', R' '' and R '' '', similar or different from each other, represent hydrogen atoms or OH groups, with this limitation that when R ', R' ', R '' 'and R' '' 'are all hydrogen atoms, R cannot be hydrogen, and their salts with pharmaceutically acceptable organic and inorganic acids. Application: medicaments which can be used as antiulcer, antispasmodic and / or spasmolytic drugs.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT03474/77A IT1080455B (en) | 1977-06-17 | 1977-06-17 | N 3 FENILTIOPROPIL 3.3 DIPHENYL REPLACED PROPILAMINS EQUIPPED WITH PHARMACOLOGY ACTIVITIES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2394527A1 true FR2394527A1 (en) | 1979-01-12 |
| FR2394527B1 FR2394527B1 (en) | 1980-06-20 |
Family
ID=11108046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7817593A Granted FR2394527A1 (en) | 1977-06-17 | 1978-06-13 | N- (3'-PHENYLTHIOPROPYL) -3,3-DIPHENYLPROPYLAMINES SUBSTITUTED WITH PHARMACOLOGICAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5430142A (en) |
| AT (1) | AT357141B (en) |
| BE (1) | BE867570A (en) |
| DE (1) | DE2825447A1 (en) |
| DK (1) | DK144064C (en) |
| ES (1) | ES470845A1 (en) |
| FR (1) | FR2394527A1 (en) |
| GB (1) | GB1561679A (en) |
| GR (1) | GR73140B (en) |
| IT (1) | IT1080455B (en) |
| NL (1) | NL7805617A (en) |
| NO (1) | NO145097C (en) |
| PT (1) | PT68122A (en) |
| SE (1) | SE7806945L (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2015197C (en) * | 1990-04-23 | 1999-08-24 | Kowichi Jimbow | Phenolic amine depigmenting and antimelanoma agents |
| US5395611A (en) * | 1990-04-24 | 1995-03-07 | The Governors Of The University Of Alberta | Phenolic amine depigmenting and antimelanoma agents |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2145639A1 (en) * | 1971-07-15 | 1973-02-23 | Alfa Farmaceutici Spa |
-
1977
- 1977-06-17 IT IT03474/77A patent/IT1080455B/en active
-
1978
- 1978-05-24 NL NL7805617A patent/NL7805617A/en not_active Application Discontinuation
- 1978-05-25 GB GB22681/78A patent/GB1561679A/en not_active Expired
- 1978-05-29 BE BE2057020A patent/BE867570A/en unknown
- 1978-05-31 PT PT68122A patent/PT68122A/en unknown
- 1978-06-09 DE DE19782825447 patent/DE2825447A1/en not_active Withdrawn
- 1978-06-13 FR FR7817593A patent/FR2394527A1/en active Granted
- 1978-06-13 AT AT430078A patent/AT357141B/en not_active IP Right Cessation
- 1978-06-15 DK DK269278A patent/DK144064C/en active
- 1978-06-16 JP JP7310378A patent/JPS5430142A/en active Pending
- 1978-06-16 NO NO782101A patent/NO145097C/en unknown
- 1978-06-16 ES ES470845A patent/ES470845A1/en not_active Expired
- 1978-06-16 GR GR56534A patent/GR73140B/el unknown
- 1978-06-16 SE SE7806945A patent/SE7806945L/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2145639A1 (en) * | 1971-07-15 | 1973-02-23 | Alfa Farmaceutici Spa |
Also Published As
| Publication number | Publication date |
|---|---|
| DK144064C (en) | 1982-06-21 |
| NO145097B (en) | 1981-10-05 |
| GB1561679A (en) | 1980-02-27 |
| ATA430078A (en) | 1979-11-15 |
| BE867570A (en) | 1978-09-18 |
| PT68122A (en) | 1978-06-01 |
| ES470845A1 (en) | 1979-09-01 |
| SE7806945L (en) | 1978-12-18 |
| DK144064B (en) | 1981-11-30 |
| FR2394527B1 (en) | 1980-06-20 |
| JPS5430142A (en) | 1979-03-06 |
| NO145097C (en) | 1982-01-13 |
| IT1080455B (en) | 1985-05-16 |
| AT357141B (en) | 1980-06-25 |
| NO782101L (en) | 1978-12-19 |
| GR73140B (en) | 1984-02-08 |
| DE2825447A1 (en) | 1979-01-04 |
| DK269278A (en) | 1978-12-18 |
| NL7805617A (en) | 1978-12-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |