FR2392025A1 - Procede d'obtention d'intermediaires de thromboxane et intermediaires obtenus - Google Patents

Procede d'obtention d'intermediaires de thromboxane et intermediaires obtenus

Info

Publication number
FR2392025A1
FR2392025A1 FR7711349A FR7711349A FR2392025A1 FR 2392025 A1 FR2392025 A1 FR 2392025A1 FR 7711349 A FR7711349 A FR 7711349A FR 7711349 A FR7711349 A FR 7711349A FR 2392025 A1 FR2392025 A1 FR 2392025A1
Authority
FR
France
Prior art keywords
intermediaries
thromboxane
procedure
obtaining
mammals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7711349A
Other languages
English (en)
Other versions
FR2392025B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2392025A1 publication Critical patent/FR2392025A1/fr
Application granted granted Critical
Publication of FR2392025B1 publication Critical patent/FR2392025B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/20—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hydrogen atoms and substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D309/22—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procédé de préparation d'un intermédiaire de thromboxane. L'invention concerne également les composés intermédiaires obtenus dans ce procédé. Application à la synthèse du thromboxane connu pour ses propriétés biologiques, notamment l'influence qu'il exerce sur le cycle de la reproduction chez les mammifères.
FR7711349A 1976-04-14 1977-04-14 Procede d'obtention d'intermediaires de thromboxane et intermediaires obtenus Granted FR2392025A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/676,895 US4032542A (en) 1976-04-14 1976-04-14 4α,6-Dihydroxy-5-iodo-2.beta.-aryloxymethyl-3α-tetrahydropyranoacetic acid γ-lactone, 6-alkyl ethers

Publications (2)

Publication Number Publication Date
FR2392025A1 true FR2392025A1 (fr) 1978-12-22
FR2392025B1 FR2392025B1 (fr) 1981-12-24

Family

ID=24716467

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7711349A Granted FR2392025A1 (fr) 1976-04-14 1977-04-14 Procede d'obtention d'intermediaires de thromboxane et intermediaires obtenus

Country Status (6)

Country Link
US (1) US4032542A (fr)
JP (1) JPS52125156A (fr)
CH (1) CH634065A5 (fr)
DE (1) DE2715920A1 (fr)
FR (1) FR2392025A1 (fr)
GB (1) GB1534985A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4083854A (en) * 1976-04-14 1978-04-11 The Upjohn Company 4,5-Didehydro-6-oxo-2-aryl-methoxymethyl-3α-tetrahydropyranacetic acids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2085653B1 (fr) * 1970-04-30 1973-06-08 Roussel Uclaf

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/76 *

Also Published As

Publication number Publication date
CH634065A5 (de) 1983-01-14
GB1534985A (en) 1978-12-06
FR2392025B1 (fr) 1981-12-24
DE2715920A1 (de) 1977-10-27
US4032542A (en) 1977-06-28
JPS52125156A (en) 1977-10-20

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Legal Events

Date Code Title Description
ST Notification of lapse