FR2383952A2 - Thiazolyl-acetyl-amino-cephem carboxylic acids - having antibiotic activity against Gram positive and negative organisms - Google Patents

Thiazolyl-acetyl-amino-cephem carboxylic acids - having antibiotic activity against Gram positive and negative organisms

Info

Publication number
FR2383952A2
FR2383952A2 FR7708173A FR7708173A FR2383952A2 FR 2383952 A2 FR2383952 A2 FR 2383952A2 FR 7708173 A FR7708173 A FR 7708173A FR 7708173 A FR7708173 A FR 7708173A FR 2383952 A2 FR2383952 A2 FR 2383952A2
Authority
FR
France
Prior art keywords
amino
thiazolyl
acetyl
carboxylic acids
activity against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7708173A
Other languages
French (fr)
Other versions
FR2383952B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7708173A priority Critical patent/FR2383952A2/en
Publication of FR2383952A2 publication Critical patent/FR2383952A2/en
Application granted granted Critical
Publication of FR2383952B2 publication Critical patent/FR2383952B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

7-Aminothiazolyl acetamido cephalosporanic acid derivs. of formula (I) are new. In (I), R is H or trityl and R1 is CH3 or acetylthiomethyl. Specific (I) are 7- 2-(2-tritylamino-4-thiazolyl) methoxyiminoacetyl amino 3-methyl ceph-3-cm. 4-carboxylic acid anti isomer or its diethylamine salt, 3-acetyl thio methyl 7- 2- 2-tritylamino-4-thiazolyl)-2-methoxyimine acetyl amino ceph-3-em-4-carboxylic acid anti isomer, 7- 2- 2-amino-4-thiazolyl)-2-methoxyimine acetyl amino 3-methyl ceph-3-em-4-carboxylic acid and anti isomer, and 3-acetyl thio methyl 7- 2- 2-amino-4-thiazolyl)-2-methoxyimine acetyl amino ceph-3-em-4-carboxylic acid anti isomer.
FR7708173A 1977-03-18 1977-03-18 Thiazolyl-acetyl-amino-cephem carboxylic acids - having antibiotic activity against Gram positive and negative organisms Granted FR2383952A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7708173A FR2383952A2 (en) 1977-03-18 1977-03-18 Thiazolyl-acetyl-amino-cephem carboxylic acids - having antibiotic activity against Gram positive and negative organisms

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7708173A FR2383952A2 (en) 1977-03-18 1977-03-18 Thiazolyl-acetyl-amino-cephem carboxylic acids - having antibiotic activity against Gram positive and negative organisms

Publications (2)

Publication Number Publication Date
FR2383952A2 true FR2383952A2 (en) 1978-10-13
FR2383952B2 FR2383952B2 (en) 1980-03-21

Family

ID=9188296

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7708173A Granted FR2383952A2 (en) 1977-03-18 1977-03-18 Thiazolyl-acetyl-amino-cephem carboxylic acids - having antibiotic activity against Gram positive and negative organisms

Country Status (1)

Country Link
FR (1) FR2383952A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0257275A2 (en) * 1986-07-28 1988-03-02 American Cyanamid Company Cephalosporin and penicillin derivatives
US5066799A (en) * 1986-07-28 1991-11-19 American Cyanamid Company Intermediates for the preparation of aminothiazoloximino cephalosporins

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0257275A2 (en) * 1986-07-28 1988-03-02 American Cyanamid Company Cephalosporin and penicillin derivatives
EP0257275A3 (en) * 1986-07-28 1990-05-23 American Cyanamid Company Cephalosporin and penicillin derivatives
US5066799A (en) * 1986-07-28 1991-11-19 American Cyanamid Company Intermediates for the preparation of aminothiazoloximino cephalosporins

Also Published As

Publication number Publication date
FR2383952B2 (en) 1980-03-21

Similar Documents

Publication Publication Date Title
AU511680B2 (en) Oxime derivatives of 7-amino thiazolyl acetamido cephalosporanic acid
IE41918L (en) 3-thio-cephalosporins.
GR63125B (en) Preparation process of novel aleoyloximes derivatives of 7-amino thiazolyl acetamido cephalosporin acid
GB2000138A (en) Therapeutic agents
GB1449420A (en) 7alpha-methoxycephalosporing derivatives
AU520898B2 (en) Crystalline sodium salt ofthe oxime derivative of 7-amino thiazolyl acetamido celphalosporanic acid
IE782546L (en) Amino-thiazolyl cephalosporins
IE39549B1 (en) Ureido-aryl cephalosporin compounds
FR2383952A2 (en) Thiazolyl-acetyl-amino-cephem carboxylic acids - having antibiotic activity against Gram positive and negative organisms
AU520450B2 (en) Oxime derivatives of 7-aminothiazolyl acetamido cephalosporanic acid
SE8104771L (en) cephalosporin derivatives
GB1493676A (en) Antibiotic method and pharmaceutical compositions
ES459945A1 (en) 7-{8 {60 -(2,3-DIHYDRO-2-OXO-1H-benzimidazol-1-ylcarbonyl-amino)arylacetamido{9 cephalosporins
GB1531141A (en) Beta-lactam antibiotics
ES470333A1 (en) Clavulanic acid derivatives
IE44605L (en) Cephalosporin derivatives
GB1073996A (en) 7-(substituted thioacylamino) cephalosporanic acid and derivatives thereof
ES8100299A1 (en) Crystalline salt of 7 beta -[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid and HCl or HBr
GB1392265A (en) Chemical products
GB1017624A (en) Cephalosporin compounds
IE39373L (en) 3-(substituted-ethyl)-cephalosporin derivatives
JPS5111782A (en) 77 aminosefuemujudotaino seizoho
SE7703689L (en) CEPHALOSPORINER
ES464008A1 (en) Monocyclic beta-lactams with antibacterial activity
IE40206B1 (en) Derivatives of cephalosporin