FR2383164A1 - Nouveaux polypeptides analogues de la b-endorphine et procede pour leur preparation - Google Patents

Nouveaux polypeptides analogues de la b-endorphine et procede pour leur preparation

Info

Publication number
FR2383164A1
FR2383164A1 FR7806637A FR7806637A FR2383164A1 FR 2383164 A1 FR2383164 A1 FR 2383164A1 FR 7806637 A FR7806637 A FR 7806637A FR 7806637 A FR7806637 A FR 7806637A FR 2383164 A1 FR2383164 A1 FR 2383164A1
Authority
FR
France
Prior art keywords
preparation
endorphine
new polypeptides
analogues
polypeptides analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7806637A
Other languages
English (en)
Inventor
Choh Hao Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2383164A1 publication Critical patent/FR2383164A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/675—Beta-endorphins
    • C07K14/6755—Beta-endorphins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne de nouveaux polypeptides et un procédé pour leur préparation. Ces nouveaux polypeptides répondent à la séquence beta -endorphine-(1-5)-(16- 31) ou ØD-Ala** 2õ- beta -endorphine-(1-5)-(l6-Ils sont utiles comme médicaments.
FR7806637A 1977-03-11 1978-03-08 Nouveaux polypeptides analogues de la b-endorphine et procede pour leur preparation Withdrawn FR2383164A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/776,568 US4081434A (en) 1977-03-11 1977-03-11 Novel analogs of β-endorphin

Publications (1)

Publication Number Publication Date
FR2383164A1 true FR2383164A1 (fr) 1978-10-06

Family

ID=25107765

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7806637A Withdrawn FR2383164A1 (fr) 1977-03-11 1978-03-08 Nouveaux polypeptides analogues de la b-endorphine et procede pour leur preparation

Country Status (19)

Country Link
US (2) US4081434A (fr)
JP (1) JPS53112801A (fr)
AT (1) AT359660B (fr)
AU (1) AU3405578A (fr)
BE (1) BE864739A (fr)
CA (1) CA1098514A (fr)
DE (1) DE2810278A1 (fr)
DK (1) DK109478A (fr)
FR (1) FR2383164A1 (fr)
GB (1) GB1594039A (fr)
IE (1) IE46480B1 (fr)
IL (1) IL54238A (fr)
IT (1) IT1202740B (fr)
LU (1) LU79211A1 (fr)
NL (1) NL7802673A (fr)
NZ (1) NZ186661A (fr)
PH (1) PH12909A (fr)
SE (1) SE7802786L (fr)
ZA (1) ZA781385B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4116950A (en) * 1978-01-16 1978-09-26 Hoffmann-La Roche Inc. Analogs of human β-endorphin
DE2960258D1 (en) * 1978-03-02 1981-05-07 Akzo Nv Psychopharmacological peptides, process for their preparation and their pharmaceutical formulations
US4396606A (en) * 1979-11-05 1983-08-02 Addiction Research Foundation Novel polypeptide analgesics
US4438104A (en) 1980-01-03 1984-03-20 Endorphin, Inc. Endorphins having placental or pancreatic origin
US4316895A (en) * 1980-01-03 1982-02-23 Kimball Charles D Endorphins having placental or pancreatic origin
US4469631A (en) * 1980-03-10 1984-09-04 The Regents Of The University Of California Fusion peptides comprising an expressible bacterial gene and β-endorphin
US4313937A (en) * 1980-08-12 1982-02-02 Tsutomu Oyama Method for producing long-lasting analgesic effects of β-endorphin
GB2111505B (en) * 1981-06-16 1984-09-26 Charles D Kimball Endorphins having placental or pancreatic origin
US4422968A (en) * 1982-09-13 1983-12-27 The Regents Of The University Of California β-Endorphin analogs
JPH0680079B2 (ja) * 1984-11-09 1994-10-12 エーザイ株式会社 ポリペプチド
IL138214A0 (en) * 1998-03-09 2001-10-31 Zealand Pharmaceuticals As Pharmacolgically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
AU2005286733B2 (en) * 2004-09-23 2009-11-05 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
US20080045610A1 (en) * 2004-09-23 2008-02-21 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
KR20060119373A (ko) * 2005-05-20 2006-11-24 엘지전자 주식회사 컴퓨터 시스템과 시스템 소프트웨어 설치방법 및 휴대용컴퓨터의 소프트웨어 설치방법
US20090006902A1 (en) * 2007-06-29 2009-01-01 International Business Machines Corporation Methods, systems, and computer program products for reporting fru failures in storage device enclosures

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038222A (en) * 1976-03-17 1977-07-26 Hoffman-La Roche Inc. Untriakontapeptide with opiate activity
FR2355804A1 (fr) * 1976-06-21 1978-01-20 Ici Ltd Nouveau polypeptide, son procede de preparation et composition pharmaceutique le contenant

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038222A (en) * 1976-03-17 1977-07-26 Hoffman-La Roche Inc. Untriakontapeptide with opiate activity
FR2355804A1 (fr) * 1976-06-21 1978-01-20 Ici Ltd Nouveau polypeptide, son procede de preparation et composition pharmaceutique le contenant

Also Published As

Publication number Publication date
LU79211A1 (fr) 1979-05-25
IT7821117A0 (it) 1978-03-10
GB1594039A (en) 1981-07-30
DK109478A (da) 1978-09-12
ZA781385B (en) 1979-02-28
IE46480B1 (en) 1983-06-29
BE864739A (fr) 1978-09-11
DE2810278A1 (de) 1978-09-14
NL7802673A (nl) 1978-09-13
ATA174678A (de) 1980-04-15
PH12909A (en) 1979-10-04
AT359660B (de) 1980-11-25
US4098778A (en) 1978-07-04
IE780494L (en) 1978-09-11
NZ186661A (en) 1981-01-23
JPS53112801A (en) 1978-10-02
IL54238A0 (en) 1978-06-15
SE7802786L (sv) 1978-09-12
US4081434A (en) 1978-03-28
CA1098514A (fr) 1981-03-31
IT1202740B (it) 1989-02-09
IL54238A (en) 1982-04-30
AU3405578A (en) 1979-09-13

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Legal Events

Date Code Title Description
ST Notification of lapse