FR2381522A1 - Drug solutions in 1-propyl 1,2-propylene glycol ether - which are stable and sterilisable for prepn. of injectable compsns. - Google Patents

Drug solutions in 1-propyl 1,2-propylene glycol ether - which are stable and sterilisable for prepn. of injectable compsns.

Info

Publication number
FR2381522A1
FR2381522A1 FR7804229A FR7804229A FR2381522A1 FR 2381522 A1 FR2381522 A1 FR 2381522A1 FR 7804229 A FR7804229 A FR 7804229A FR 7804229 A FR7804229 A FR 7804229A FR 2381522 A1 FR2381522 A1 FR 2381522A1
Authority
FR
France
Prior art keywords
propyl
propylene glycol
glycol ether
sterilisable
compsns
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7804229A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of FR2381522A1 publication Critical patent/FR2381522A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

1-Propyl-1, 2-propylene glycol ether is used as solvent for pharm. compns. Clear, conc. solns. may be prepd., which are sterilisable at 120 degrees C at atmos. pressure, esp. useful for injection. A typical soln. may be prepd. by dissolving diazepam (25mg) in 1-propyl 1,2-propylene glycol ether (3 ml) and diluting to a suitable volume with 0.9% NaCl soln.
FR7804229A 1977-02-26 1978-02-15 Drug solutions in 1-propyl 1,2-propylene glycol ether - which are stable and sterilisable for prepn. of injectable compsns. Withdrawn FR2381522A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2708420 1977-02-26

Publications (1)

Publication Number Publication Date
FR2381522A1 true FR2381522A1 (en) 1978-09-22

Family

ID=6002246

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7804229A Withdrawn FR2381522A1 (en) 1977-02-26 1978-02-15 Drug solutions in 1-propyl 1,2-propylene glycol ether - which are stable and sterilisable for prepn. of injectable compsns.

Country Status (3)

Country Link
BE (1) BE863935A (en)
FR (1) FR2381522A1 (en)
NL (1) NL7801939A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2597342A1 (en) * 1986-04-16 1987-10-23 Oreal STABLE ANTI-ACNEIC COMPOSITION BASED ON ERYTHROMYCIN.

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE333357A (en) *
DE446290C (en) * 1925-04-22 1927-06-27 Ig Farbenindustrie Ag Process for the preparation of combat solutions
DE562884C (en) * 1926-02-14 1932-10-29 Chem Ind Basel Process for the production of solutions in water of poorly soluble drugs, with the exception of camphor and sleeping pills, including hypnotic alkaloid bases
FR912505A (en) * 1944-05-02 1946-08-12 Fr De Rech S Biochimiques Soc Process for preparing solutions of stable medicinal substances
GB931420A (en) * 1961-03-20 1963-07-17 Gilbert Ancel Injectable pharmaceutical compositions comprising 1-ethyl-1-methylpropyl carbamate
BE668977A (en) * 1964-09-05 1966-02-28
FR6555M (en) * 1967-05-03 1968-12-23
NL7514554A (en) * 1974-12-12 1976-06-15 Richter Gedeon Vegyeszet PROCEDURE FOR PREPARING A MEDICINAL PRODUCT WITH INFLAMMATORY ACTION.

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE333357A (en) *
DE446290C (en) * 1925-04-22 1927-06-27 Ig Farbenindustrie Ag Process for the preparation of combat solutions
DE562884C (en) * 1926-02-14 1932-10-29 Chem Ind Basel Process for the production of solutions in water of poorly soluble drugs, with the exception of camphor and sleeping pills, including hypnotic alkaloid bases
FR912505A (en) * 1944-05-02 1946-08-12 Fr De Rech S Biochimiques Soc Process for preparing solutions of stable medicinal substances
GB931420A (en) * 1961-03-20 1963-07-17 Gilbert Ancel Injectable pharmaceutical compositions comprising 1-ethyl-1-methylpropyl carbamate
BE668977A (en) * 1964-09-05 1966-02-28
FR6555M (en) * 1967-05-03 1968-12-23
NL7514554A (en) * 1974-12-12 1976-06-15 Richter Gedeon Vegyeszet PROCEDURE FOR PREPARING A MEDICINAL PRODUCT WITH INFLAMMATORY ACTION.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2597342A1 (en) * 1986-04-16 1987-10-23 Oreal STABLE ANTI-ACNEIC COMPOSITION BASED ON ERYTHROMYCIN.
BE1000153A4 (en) * 1986-04-16 1988-05-31 Oreal Anti-acne STABLE COMPOSITION BASED ERYTHROMYCIN.

Also Published As

Publication number Publication date
NL7801939A (en) 1978-08-29
BE863935A (en) 1978-08-14

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Legal Events

Date Code Title Description
RE Withdrawal of published application