FR2373549B1 - - Google Patents

Info

Publication number
FR2373549B1
FR2373549B1 FR7736436A FR7736436A FR2373549B1 FR 2373549 B1 FR2373549 B1 FR 2373549B1 FR 7736436 A FR7736436 A FR 7736436A FR 7736436 A FR7736436 A FR 7736436A FR 2373549 B1 FR2373549 B1 FR 2373549B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7736436A
Other versions
FR2373549A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2373549A1 publication Critical patent/FR2373549A1/fr
Application granted granted Critical
Publication of FR2373549B1 publication Critical patent/FR2373549B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7736436A 1976-12-08 1977-12-02 Procede de transformation de 3-methylenecephalosporines en 3-heterothiomethylcephalosporines Granted FR2373549A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/748,426 US4129731A (en) 1976-12-08 1976-12-08 Process for converting 3-methylene cephalosporins to 3-heterothiomethyl cephalosporins

Publications (2)

Publication Number Publication Date
FR2373549A1 FR2373549A1 (fr) 1978-07-07
FR2373549B1 true FR2373549B1 (fr) 1980-12-05

Family

ID=25009398

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7736436A Granted FR2373549A1 (fr) 1976-12-08 1977-12-02 Procede de transformation de 3-methylenecephalosporines en 3-heterothiomethylcephalosporines

Country Status (11)

Country Link
US (1) US4129731A (fr)
JP (1) JPS5373597A (fr)
AU (1) AU511186B2 (fr)
BE (1) BE861639A (fr)
CA (1) CA1087169A (fr)
CH (1) CH626089A5 (fr)
DE (1) DE2754742C2 (fr)
FR (1) FR2373549A1 (fr)
GB (1) GB1591460A (fr)
IE (1) IE46175B1 (fr)
NL (1) NL7712900A (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311837A (en) * 1979-05-01 1982-01-19 Eli Lilly And Company Certain heterocyclic thiomethyl derivatives of 7-(dihalogenated phenylthioacetamido)cephalosporanic acids useful in the treatment of infections caused by _Streptococcus faecalis
NL8005041A (nl) * 1980-09-05 1982-04-01 Gist Brocades Nv Werkwijze voor de bereiding van thioethers, alsmede gesilyleerde thiolen voor toepassing bij deze werkwijze.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3275626A (en) * 1962-07-31 1966-09-27 Lilly Co Eli Penicillin conversion via sulfoxide
US3929775A (en) * 1970-12-08 1975-12-30 Takeda Chemical Industries Ltd Process for producing cephalosporin derivatives
CS183696B2 (en) * 1971-02-25 1978-07-31 Robert R Chauvette Method for producing derivatives of 3-methyl-delta up3-cephem-4-carboxylic acid
JPS515396B1 (fr) * 1971-04-05 1976-02-19
US3883518A (en) * 1972-05-15 1975-05-13 Merck & Co Inc 3-Methylene cephalosporins
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
US3962227A (en) * 1973-02-23 1976-06-08 Eli Lilly And Company 3-halo cephalosporins
US3941779A (en) * 1973-11-12 1976-03-02 E. R. Squibb & Sons, Inc. Method for producing 2-(substituted thio)-3-cephem derivatives
US3968109A (en) * 1973-11-23 1976-07-06 E. R. Squibb & Sons, Inc. Production of 2-(thio substituted)cephalosporin sulfoxides and 2-(thio substituted)cephalosporins
US4049806A (en) * 1975-08-15 1977-09-20 Syntex (U.S.A.) Inc. Cephalosporin type antibacterials
US4039534A (en) * 1975-11-17 1977-08-02 E. R. Squibb & Sons, Inc. 4-Thio substituted-Δ2 -cephalosporin intermediates

Also Published As

Publication number Publication date
JPS6118554B2 (fr) 1986-05-13
JPS5373597A (en) 1978-06-30
CH626089A5 (fr) 1981-10-30
IE46175L (en) 1978-06-08
GB1591460A (en) 1981-06-24
IE46175B1 (en) 1983-03-23
AU511186B2 (en) 1980-07-31
DE2754742A1 (de) 1978-06-15
US4129731A (en) 1978-12-12
DE2754742C2 (de) 1986-04-30
BE861639A (fr) 1978-06-08
NL7712900A (nl) 1978-06-12
FR2373549A1 (fr) 1978-07-07
AU3038677A (en) 1979-05-17
CA1087169A (fr) 1980-10-07

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Legal Events

Date Code Title Description
ST Notification of lapse