FR2372635A1 - Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorption - Google Patents

Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorption

Info

Publication number
FR2372635A1
FR2372635A1 FR7736418A FR7736418A FR2372635A1 FR 2372635 A1 FR2372635 A1 FR 2372635A1 FR 7736418 A FR7736418 A FR 7736418A FR 7736418 A FR7736418 A FR 7736418A FR 2372635 A1 FR2372635 A1 FR 2372635A1
Authority
FR
France
Prior art keywords
capsules
silicone
self
admin
contg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7736418A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent UK Swindon Encaps Ltd
Original Assignee
Catalent UK Swindon Encaps Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent UK Swindon Encaps Ltd filed Critical Catalent UK Swindon Encaps Ltd
Publication of FR2372635A1 publication Critical patent/FR2372635A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pharmaceutical compsn. contains a unit dose of the active ingredient (I) and a self-emulsifying oil (II). Suitable (II) are steroids; antimycotics; tranquilisers, sedatives; diuretics; anti-inflammatories; analgesics; antibiotics and insulin; specifically dexamethasone, prednisolone, griseofulvin, diazepam, chlordiazepoxide, furosemide, indomethacin, lipophilic penicillins and bleomycin. (I) and (II) are presented in soln. or suspension, and (II) consists of an oil (IIa), e.g. a silicone or triglyceride, and a surfactant (IIb), pref. nonionic e.g. polyethoxylated alkylphenols. For rectal, vaginal and esp. oral administration; the compsns. can be filled into capsules to give highly reproducible doses, and when ingested have improved resorption from the gastro-intestinal tract.
FR7736418A 1976-12-03 1977-12-02 Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorption Withdrawn FR2372635A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5057776 1976-12-03

Publications (1)

Publication Number Publication Date
FR2372635A1 true FR2372635A1 (en) 1978-06-30

Family

ID=10456450

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7736418A Withdrawn FR2372635A1 (en) 1976-12-03 1977-12-02 Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorption

Country Status (5)

Country Link
JP (1) JPS5372814A (en)
AU (1) AU3111677A (en)
DE (1) DE2753526A1 (en)
FR (1) FR2372635A1 (en)
IT (1) IT1090703B (en)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2491333A1 (en) * 1980-10-06 1982-04-09 Glaxo Group Ltd TOPICALLY ADMINISTRATIVE PHARMACEUTICAL COMPOSITIONS CONTAINING ANTI-INFLAMMATORY STEROIDS
FR2500302A1 (en) * 1981-02-25 1982-08-27 Negma Laboratoires Indomethacin antiinflammatory compsn. with reduced gastric irritation - uses liquid, oil or paste excipients contg. lipid(s), opt. hydroxylated polyether oxide(s)
EP0130514A2 (en) * 1983-07-05 1985-01-09 Troponwerke GmbH & Co. KG Depot antiphlogistics
FR2549371A1 (en) * 1983-07-20 1985-01-25 Sanofi Sa New pharmaceutical composition containing valproic acid or one of its salts
EP0343575A1 (en) * 1988-05-24 1989-11-29 Günter Stephan Soft gelatin capsule
EP0517412A1 (en) * 1991-06-03 1992-12-09 MERCK SHARP & DOHME LTD. Pharmaceutical formulations of a benzodiazepine
WO1994007472A1 (en) * 1992-10-02 1994-04-14 Pfizer Inc. Pharmaceutical compositions containing nonionic surfactants
WO1995012384A1 (en) * 1993-11-02 1995-05-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Self-emulsible formulation forming an oil-in-water emulsion
WO1995024893A1 (en) * 1994-03-16 1995-09-21 R.P. Scherer Limited Delivery systems for hydrophobic drugs
WO1996019195A1 (en) * 1994-12-22 1996-06-27 Laboratoire Innothera Unitary vaginal dosage form useful as a local contraceptive and/or for combatting sexually transmitted diseases and/or hiv
WO1999056727A2 (en) * 1998-05-07 1999-11-11 Elan Corporation, Plc Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems
EP1420767A1 (en) * 2001-08-27 2004-05-26 Won Jin Biopharma Co. Ltd. Compositions containing itraconazole and their preparation methods
WO2020157675A1 (en) * 2019-01-31 2020-08-06 Gdański Uniwersytet Medyczny Z Siedzibą W Gdańsku Self-emulsifying pharmaceutical composition in the liquid form, containing as the active substance a drug substance unstable in an aqueous environment

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904182D0 (en) * 1989-02-23 1989-04-05 Glaxo Canada Pharmaceutical compositions
DE4322826A1 (en) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmaceutical preparation
JP2006521366A (en) * 2003-03-28 2006-09-21 シグモイド・バイオテクノロジーズ・リミテッド Solid oral dosage forms containing seamless microcapsules
KR101390695B1 (en) * 2006-08-01 2014-04-30 오츠카 세이야쿠 가부시키가이샤 Pharmaceutical composition improved in absorption of pharmacologically active substance
CA2683409A1 (en) 2007-04-04 2008-10-16 Sigmoid Pharma Limited A pharmaceutical composition of tacrolimus
ES2963291T3 (en) 2007-04-26 2024-03-26 Sublimity Therapeutics Ltd Manufacturing of multiple mini capsules
EP2432455B1 (en) 2009-05-18 2014-11-12 Sigmoid Pharma Limited Composition comprising oil drops
CA2770570A1 (en) 2009-08-12 2011-02-17 Sigmoid Pharma Limited Immunomodulatory compositions comprising a polymer matrix and an oil phase
GB201020032D0 (en) 2010-11-25 2011-01-12 Sigmoid Pharma Ltd Composition
JP2013545800A (en) * 2010-12-20 2013-12-26 コルゲート・パーモリブ・カンパニー Gelatin encapsulated oral care composition comprising a hydrophilic active agent, a hydrophobic structurant and an oil carrier
WO2012144943A1 (en) * 2011-04-18 2012-10-26 Lipidor Ab Liquid carrier for oral delivery of a pharmacologically active agent
MX358435B (en) * 2012-06-18 2018-08-03 Therapeuticsmd Inc Soluble estradiol capsule for vaginal insertion.
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
GB201304662D0 (en) 2013-03-14 2013-05-01 Sigmoid Pharma Ltd Compositions
GB201319791D0 (en) 2013-11-08 2013-12-25 Sigmoid Pharma Ltd Formulations
PL3215127T3 (en) 2014-11-07 2021-05-17 Sublimity Therapeutics Limited Compositions comprising cyclosporin

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE567598A (en) *
GB817241A (en) * 1957-08-21 1959-07-29 Vismara Francesco Spa Oily solutions for parenteral administration containing adreno-cortical hormones
FR5530M (en) * 1965-02-18 1967-12-18
DE2027325A1 (en) * 1969-06-03 1970-12-17 Sumitomo Chemical Company Ltd., Osaka (Japan) Pharmaceutical composition and process for its manufacture
US3708583A (en) * 1970-04-03 1973-01-02 Vitamin Premixers Of Omaha Inc Stabilized vitamin a additive
FR2266512A1 (en) * 1974-04-04 1975-10-31 Crinos Industria Farmaco
US3920819A (en) * 1974-12-02 1975-11-18 Lilly Co Eli Nonaqueous vehicle for oral pharmaceutical suspensions
NL7507745A (en) * 1974-07-04 1976-01-06 Sandoz Ag METHOD OF PREPARING A GALENIC MEDICINAL PRODUCT AND FORMED MEDICINAL PRODUCTS OBTAINED UNDER THIS METHOD.

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE567598A (en) *
GB817241A (en) * 1957-08-21 1959-07-29 Vismara Francesco Spa Oily solutions for parenteral administration containing adreno-cortical hormones
FR5530M (en) * 1965-02-18 1967-12-18
DE2027325A1 (en) * 1969-06-03 1970-12-17 Sumitomo Chemical Company Ltd., Osaka (Japan) Pharmaceutical composition and process for its manufacture
US3708583A (en) * 1970-04-03 1973-01-02 Vitamin Premixers Of Omaha Inc Stabilized vitamin a additive
FR2266512A1 (en) * 1974-04-04 1975-10-31 Crinos Industria Farmaco
NL7507745A (en) * 1974-07-04 1976-01-06 Sandoz Ag METHOD OF PREPARING A GALENIC MEDICINAL PRODUCT AND FORMED MEDICINAL PRODUCTS OBTAINED UNDER THIS METHOD.
US3920819A (en) * 1974-12-02 1975-11-18 Lilly Co Eli Nonaqueous vehicle for oral pharmaceutical suspensions

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2491333A1 (en) * 1980-10-06 1982-04-09 Glaxo Group Ltd TOPICALLY ADMINISTRATIVE PHARMACEUTICAL COMPOSITIONS CONTAINING ANTI-INFLAMMATORY STEROIDS
FR2500302A1 (en) * 1981-02-25 1982-08-27 Negma Laboratoires Indomethacin antiinflammatory compsn. with reduced gastric irritation - uses liquid, oil or paste excipients contg. lipid(s), opt. hydroxylated polyether oxide(s)
EP0130514A2 (en) * 1983-07-05 1985-01-09 Troponwerke GmbH & Co. KG Depot antiphlogistics
EP0130514A3 (en) * 1983-07-05 1986-08-13 Troponwerke GmbH & Co. KG Depot antiphlogistics
FR2549371A1 (en) * 1983-07-20 1985-01-25 Sanofi Sa New pharmaceutical composition containing valproic acid or one of its salts
EP0343575A1 (en) * 1988-05-24 1989-11-29 Günter Stephan Soft gelatin capsule
EP0517412A1 (en) * 1991-06-03 1992-12-09 MERCK SHARP & DOHME LTD. Pharmaceutical formulations of a benzodiazepine
WO1992021348A1 (en) * 1991-06-03 1992-12-10 Merck Sharp & Dohme Limited Pharmaceutical formulations of a benzodiazepine
WO1994007472A1 (en) * 1992-10-02 1994-04-14 Pfizer Inc. Pharmaceutical compositions containing nonionic surfactants
WO1995012384A1 (en) * 1993-11-02 1995-05-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Self-emulsible formulation forming an oil-in-water emulsion
WO1995024893A1 (en) * 1994-03-16 1995-09-21 R.P. Scherer Limited Delivery systems for hydrophobic drugs
US6096338A (en) * 1994-03-16 2000-08-01 R. P. Scherer Corporation Delivery systems for hydrophobic drugs
EP1205180A2 (en) * 1994-03-16 2002-05-15 R.P. Scherer Technologies, Inc. Delivery system for hydrophobic drugs
EP1205180A3 (en) * 1994-03-16 2002-11-27 R.P. Scherer Technologies, Inc. Delivery system for hydrophobic drugs
WO1996019195A1 (en) * 1994-12-22 1996-06-27 Laboratoire Innothera Unitary vaginal dosage form useful as a local contraceptive and/or for combatting sexually transmitted diseases and/or hiv
FR2728464A1 (en) * 1994-12-22 1996-06-28 Innothera Lab Sa UNITAL GALENIC FORM, PROCESS FOR OBTAINING SAME AND USES THEREOF
LT4304B (en) 1994-12-22 1998-03-25 Laboratoire Innothera Unitary vaginal dosage form useful as a local contraceptive and/or for combatting sexually transmitted diseases and/or hiv
US6664296B1 (en) 1994-12-22 2003-12-16 Laboratoire Innothera Societe Anonyme Unit galenical formulation for vaginal use as a local contraceptive and/or to combat sexually-transmitted diseases and/or HIV
WO1999056727A2 (en) * 1998-05-07 1999-11-11 Elan Corporation, Plc Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems
WO1999056727A3 (en) * 1998-05-07 2000-03-02 Elan Corp Plc Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems
EP1420767A1 (en) * 2001-08-27 2004-05-26 Won Jin Biopharma Co. Ltd. Compositions containing itraconazole and their preparation methods
EP1420767A4 (en) * 2001-08-27 2004-11-24 Won Jin Biopharma Co Ltd Compositions containing itraconazole and their preparation methods
WO2020157675A1 (en) * 2019-01-31 2020-08-06 Gdański Uniwersytet Medyczny Z Siedzibą W Gdańsku Self-emulsifying pharmaceutical composition in the liquid form, containing as the active substance a drug substance unstable in an aqueous environment

Also Published As

Publication number Publication date
AU3111677A (en) 1979-06-07
DE2753526A1 (en) 1978-06-08
JPS5372814A (en) 1978-06-28
IT1090703B (en) 1985-06-26

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