FR2372635A1 - Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorption - Google Patents
Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorptionInfo
- Publication number
- FR2372635A1 FR2372635A1 FR7736418A FR7736418A FR2372635A1 FR 2372635 A1 FR2372635 A1 FR 2372635A1 FR 7736418 A FR7736418 A FR 7736418A FR 7736418 A FR7736418 A FR 7736418A FR 2372635 A1 FR2372635 A1 FR 2372635A1
- Authority
- FR
- France
- Prior art keywords
- capsules
- silicone
- self
- admin
- contg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Pharmaceutical compsn. contains a unit dose of the active ingredient (I) and a self-emulsifying oil (II). Suitable (II) are steroids; antimycotics; tranquilisers, sedatives; diuretics; anti-inflammatories; analgesics; antibiotics and insulin; specifically dexamethasone, prednisolone, griseofulvin, diazepam, chlordiazepoxide, furosemide, indomethacin, lipophilic penicillins and bleomycin. (I) and (II) are presented in soln. or suspension, and (II) consists of an oil (IIa), e.g. a silicone or triglyceride, and a surfactant (IIb), pref. nonionic e.g. polyethoxylated alkylphenols. For rectal, vaginal and esp. oral administration; the compsns. can be filled into capsules to give highly reproducible doses, and when ingested have improved resorption from the gastro-intestinal tract.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5057776 | 1976-12-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2372635A1 true FR2372635A1 (en) | 1978-06-30 |
Family
ID=10456450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7736418A Withdrawn FR2372635A1 (en) | 1976-12-03 | 1977-12-02 | Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorption |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS5372814A (en) |
AU (1) | AU3111677A (en) |
DE (1) | DE2753526A1 (en) |
FR (1) | FR2372635A1 (en) |
IT (1) | IT1090703B (en) |
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2491333A1 (en) * | 1980-10-06 | 1982-04-09 | Glaxo Group Ltd | TOPICALLY ADMINISTRATIVE PHARMACEUTICAL COMPOSITIONS CONTAINING ANTI-INFLAMMATORY STEROIDS |
FR2500302A1 (en) * | 1981-02-25 | 1982-08-27 | Negma Laboratoires | Indomethacin antiinflammatory compsn. with reduced gastric irritation - uses liquid, oil or paste excipients contg. lipid(s), opt. hydroxylated polyether oxide(s) |
EP0130514A2 (en) * | 1983-07-05 | 1985-01-09 | Troponwerke GmbH & Co. KG | Depot antiphlogistics |
FR2549371A1 (en) * | 1983-07-20 | 1985-01-25 | Sanofi Sa | New pharmaceutical composition containing valproic acid or one of its salts |
EP0343575A1 (en) * | 1988-05-24 | 1989-11-29 | Günter Stephan | Soft gelatin capsule |
EP0517412A1 (en) * | 1991-06-03 | 1992-12-09 | MERCK SHARP & DOHME LTD. | Pharmaceutical formulations of a benzodiazepine |
WO1994007472A1 (en) * | 1992-10-02 | 1994-04-14 | Pfizer Inc. | Pharmaceutical compositions containing nonionic surfactants |
WO1995012384A1 (en) * | 1993-11-02 | 1995-05-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Self-emulsible formulation forming an oil-in-water emulsion |
WO1995024893A1 (en) * | 1994-03-16 | 1995-09-21 | R.P. Scherer Limited | Delivery systems for hydrophobic drugs |
WO1996019195A1 (en) * | 1994-12-22 | 1996-06-27 | Laboratoire Innothera | Unitary vaginal dosage form useful as a local contraceptive and/or for combatting sexually transmitted diseases and/or hiv |
WO1999056727A2 (en) * | 1998-05-07 | 1999-11-11 | Elan Corporation, Plc | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
EP1420767A1 (en) * | 2001-08-27 | 2004-05-26 | Won Jin Biopharma Co. Ltd. | Compositions containing itraconazole and their preparation methods |
WO2020157675A1 (en) * | 2019-01-31 | 2020-08-06 | Gdański Uniwersytet Medyczny Z Siedzibą W Gdańsku | Self-emulsifying pharmaceutical composition in the liquid form, containing as the active substance a drug substance unstable in an aqueous environment |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8904182D0 (en) * | 1989-02-23 | 1989-04-05 | Glaxo Canada | Pharmaceutical compositions |
DE4322826A1 (en) * | 1993-07-08 | 1995-01-12 | Galenik Labor Freiburg Gmbh | Pharmaceutical preparation |
JP2006521366A (en) * | 2003-03-28 | 2006-09-21 | シグモイド・バイオテクノロジーズ・リミテッド | Solid oral dosage forms containing seamless microcapsules |
KR101390695B1 (en) * | 2006-08-01 | 2014-04-30 | 오츠카 세이야쿠 가부시키가이샤 | Pharmaceutical composition improved in absorption of pharmacologically active substance |
CA2683409A1 (en) | 2007-04-04 | 2008-10-16 | Sigmoid Pharma Limited | A pharmaceutical composition of tacrolimus |
ES2963291T3 (en) | 2007-04-26 | 2024-03-26 | Sublimity Therapeutics Ltd | Manufacturing of multiple mini capsules |
EP2432455B1 (en) | 2009-05-18 | 2014-11-12 | Sigmoid Pharma Limited | Composition comprising oil drops |
CA2770570A1 (en) | 2009-08-12 | 2011-02-17 | Sigmoid Pharma Limited | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
JP2013545800A (en) * | 2010-12-20 | 2013-12-26 | コルゲート・パーモリブ・カンパニー | Gelatin encapsulated oral care composition comprising a hydrophilic active agent, a hydrophobic structurant and an oil carrier |
WO2012144943A1 (en) * | 2011-04-18 | 2012-10-26 | Lipidor Ab | Liquid carrier for oral delivery of a pharmacologically active agent |
MX358435B (en) * | 2012-06-18 | 2018-08-03 | Therapeuticsmd Inc | Soluble estradiol capsule for vaginal insertion. |
GB201212010D0 (en) | 2012-07-05 | 2012-08-22 | Sigmoid Pharma Ltd | Formulations |
GB201304662D0 (en) | 2013-03-14 | 2013-05-01 | Sigmoid Pharma Ltd | Compositions |
GB201319791D0 (en) | 2013-11-08 | 2013-12-25 | Sigmoid Pharma Ltd | Formulations |
PL3215127T3 (en) | 2014-11-07 | 2021-05-17 | Sublimity Therapeutics Limited | Compositions comprising cyclosporin |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE567598A (en) * | ||||
GB817241A (en) * | 1957-08-21 | 1959-07-29 | Vismara Francesco Spa | Oily solutions for parenteral administration containing adreno-cortical hormones |
FR5530M (en) * | 1965-02-18 | 1967-12-18 | ||
DE2027325A1 (en) * | 1969-06-03 | 1970-12-17 | Sumitomo Chemical Company Ltd., Osaka (Japan) | Pharmaceutical composition and process for its manufacture |
US3708583A (en) * | 1970-04-03 | 1973-01-02 | Vitamin Premixers Of Omaha Inc | Stabilized vitamin a additive |
FR2266512A1 (en) * | 1974-04-04 | 1975-10-31 | Crinos Industria Farmaco | |
US3920819A (en) * | 1974-12-02 | 1975-11-18 | Lilly Co Eli | Nonaqueous vehicle for oral pharmaceutical suspensions |
NL7507745A (en) * | 1974-07-04 | 1976-01-06 | Sandoz Ag | METHOD OF PREPARING A GALENIC MEDICINAL PRODUCT AND FORMED MEDICINAL PRODUCTS OBTAINED UNDER THIS METHOD. |
-
1977
- 1977-11-25 IT IT5195677A patent/IT1090703B/en active
- 1977-12-01 AU AU31116/77A patent/AU3111677A/en active Pending
- 1977-12-01 DE DE19772753526 patent/DE2753526A1/en active Pending
- 1977-12-02 FR FR7736418A patent/FR2372635A1/en not_active Withdrawn
- 1977-12-02 JP JP14492177A patent/JPS5372814A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE567598A (en) * | ||||
GB817241A (en) * | 1957-08-21 | 1959-07-29 | Vismara Francesco Spa | Oily solutions for parenteral administration containing adreno-cortical hormones |
FR5530M (en) * | 1965-02-18 | 1967-12-18 | ||
DE2027325A1 (en) * | 1969-06-03 | 1970-12-17 | Sumitomo Chemical Company Ltd., Osaka (Japan) | Pharmaceutical composition and process for its manufacture |
US3708583A (en) * | 1970-04-03 | 1973-01-02 | Vitamin Premixers Of Omaha Inc | Stabilized vitamin a additive |
FR2266512A1 (en) * | 1974-04-04 | 1975-10-31 | Crinos Industria Farmaco | |
NL7507745A (en) * | 1974-07-04 | 1976-01-06 | Sandoz Ag | METHOD OF PREPARING A GALENIC MEDICINAL PRODUCT AND FORMED MEDICINAL PRODUCTS OBTAINED UNDER THIS METHOD. |
US3920819A (en) * | 1974-12-02 | 1975-11-18 | Lilly Co Eli | Nonaqueous vehicle for oral pharmaceutical suspensions |
Cited By (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2491333A1 (en) * | 1980-10-06 | 1982-04-09 | Glaxo Group Ltd | TOPICALLY ADMINISTRATIVE PHARMACEUTICAL COMPOSITIONS CONTAINING ANTI-INFLAMMATORY STEROIDS |
FR2500302A1 (en) * | 1981-02-25 | 1982-08-27 | Negma Laboratoires | Indomethacin antiinflammatory compsn. with reduced gastric irritation - uses liquid, oil or paste excipients contg. lipid(s), opt. hydroxylated polyether oxide(s) |
EP0130514A2 (en) * | 1983-07-05 | 1985-01-09 | Troponwerke GmbH & Co. KG | Depot antiphlogistics |
EP0130514A3 (en) * | 1983-07-05 | 1986-08-13 | Troponwerke GmbH & Co. KG | Depot antiphlogistics |
FR2549371A1 (en) * | 1983-07-20 | 1985-01-25 | Sanofi Sa | New pharmaceutical composition containing valproic acid or one of its salts |
EP0343575A1 (en) * | 1988-05-24 | 1989-11-29 | Günter Stephan | Soft gelatin capsule |
EP0517412A1 (en) * | 1991-06-03 | 1992-12-09 | MERCK SHARP & DOHME LTD. | Pharmaceutical formulations of a benzodiazepine |
WO1992021348A1 (en) * | 1991-06-03 | 1992-12-10 | Merck Sharp & Dohme Limited | Pharmaceutical formulations of a benzodiazepine |
WO1994007472A1 (en) * | 1992-10-02 | 1994-04-14 | Pfizer Inc. | Pharmaceutical compositions containing nonionic surfactants |
WO1995012384A1 (en) * | 1993-11-02 | 1995-05-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Self-emulsible formulation forming an oil-in-water emulsion |
WO1995024893A1 (en) * | 1994-03-16 | 1995-09-21 | R.P. Scherer Limited | Delivery systems for hydrophobic drugs |
US6096338A (en) * | 1994-03-16 | 2000-08-01 | R. P. Scherer Corporation | Delivery systems for hydrophobic drugs |
EP1205180A2 (en) * | 1994-03-16 | 2002-05-15 | R.P. Scherer Technologies, Inc. | Delivery system for hydrophobic drugs |
EP1205180A3 (en) * | 1994-03-16 | 2002-11-27 | R.P. Scherer Technologies, Inc. | Delivery system for hydrophobic drugs |
WO1996019195A1 (en) * | 1994-12-22 | 1996-06-27 | Laboratoire Innothera | Unitary vaginal dosage form useful as a local contraceptive and/or for combatting sexually transmitted diseases and/or hiv |
FR2728464A1 (en) * | 1994-12-22 | 1996-06-28 | Innothera Lab Sa | UNITAL GALENIC FORM, PROCESS FOR OBTAINING SAME AND USES THEREOF |
LT4304B (en) | 1994-12-22 | 1998-03-25 | Laboratoire Innothera | Unitary vaginal dosage form useful as a local contraceptive and/or for combatting sexually transmitted diseases and/or hiv |
US6664296B1 (en) | 1994-12-22 | 2003-12-16 | Laboratoire Innothera Societe Anonyme | Unit galenical formulation for vaginal use as a local contraceptive and/or to combat sexually-transmitted diseases and/or HIV |
WO1999056727A2 (en) * | 1998-05-07 | 1999-11-11 | Elan Corporation, Plc | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
WO1999056727A3 (en) * | 1998-05-07 | 2000-03-02 | Elan Corp Plc | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
EP1420767A1 (en) * | 2001-08-27 | 2004-05-26 | Won Jin Biopharma Co. Ltd. | Compositions containing itraconazole and their preparation methods |
EP1420767A4 (en) * | 2001-08-27 | 2004-11-24 | Won Jin Biopharma Co Ltd | Compositions containing itraconazole and their preparation methods |
WO2020157675A1 (en) * | 2019-01-31 | 2020-08-06 | Gdański Uniwersytet Medyczny Z Siedzibą W Gdańsku | Self-emulsifying pharmaceutical composition in the liquid form, containing as the active substance a drug substance unstable in an aqueous environment |
Also Published As
Publication number | Publication date |
---|---|
AU3111677A (en) | 1979-06-07 |
DE2753526A1 (en) | 1978-06-08 |
JPS5372814A (en) | 1978-06-28 |
IT1090703B (en) | 1985-06-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |