FR2366015A1 - Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation - Google Patents
Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparationInfo
- Publication number
- FR2366015A1 FR2366015A1 FR7533847A FR7533847A FR2366015A1 FR 2366015 A1 FR2366015 A1 FR 2366015A1 FR 7533847 A FR7533847 A FR 7533847A FR 7533847 A FR7533847 A FR 7533847A FR 2366015 A1 FR2366015 A1 FR 2366015A1
- Authority
- FR
- France
- Prior art keywords
- amino
- benzoyl
- phenylacetic acid
- antiinflammatory
- blood platelet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 3
- 238000005054 agglomeration Methods 0.000 title abstract 2
- 230000002776 aggregation Effects 0.000 title abstract 2
- 210000001772 blood platelet Anatomy 0.000 title abstract 2
- BKINSLVMGNLMOJ-UHFFFAOYSA-N 2-amino-3-oxo-2,3-diphenylpropanoic acid Chemical compound C(C1=CC=CC=C1)(=O)C(C(=O)O)(C1=CC=CC=C1)N BKINSLVMGNLMOJ-UHFFFAOYSA-N 0.000 title 1
- 230000000871 hypocholesterolemic effect Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- VZIGJQLPRYUGEZ-UHFFFAOYSA-N 2-(2-amino-6-benzoylphenyl)acetic acid Chemical compound NC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1CC(O)=O VZIGJQLPRYUGEZ-UHFFFAOYSA-N 0.000 abstract 1
- UHFMFTZBWIASIV-UHFFFAOYSA-N 2-(4-amino-3-benzoylphenyl)acetic acid Chemical compound NC1=CC=C(CC(O)=O)C=C1C(=O)C1=CC=CC=C1 UHFMFTZBWIASIV-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- SOYCMDCMZDHQFP-UHFFFAOYSA-N amfenac Chemical compound NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=CC=C1 SOYCMDCMZDHQFP-UHFFFAOYSA-N 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- -1 di-methylamino Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7533847A FR2366015A1 (fr) | 1975-11-05 | 1975-11-05 | Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7533847A FR2366015A1 (fr) | 1975-11-05 | 1975-11-05 | Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2366015A1 true FR2366015A1 (fr) | 1978-04-28 |
| FR2366015B1 FR2366015B1 (enExample) | 1979-03-02 |
Family
ID=9162073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7533847A Granted FR2366015A1 (fr) | 1975-11-05 | 1975-11-05 | Nouveaux acides amino-2 benzoyl-3 (5 et 6) phenylacetiques et leurs esters et sels de metaux alcalins, utiles notamment comme anti-inflammatoires, et leur procede de preparation |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2366015A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2476071A1 (fr) * | 1980-02-19 | 1981-08-21 | Robins Co Inc A H | Nouveaux acides 2-amino-3-(a-hydroxybenzyl)-phenylacetiques et leurs esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant |
| FR2499981A1 (fr) * | 1981-02-17 | 1982-08-20 | Robins Co Inc A H | Acides amino-2 halogenobenzoyl-3 methylphenylacetiques et leurs esters et sels utiles comme medicaments anti-inflammatoires et analgesiques |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2184934A1 (enExample) * | 1975-08-13 | 1973-12-28 | Robins Co Inc A H |
-
1975
- 1975-11-05 FR FR7533847A patent/FR2366015A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2184934A1 (enExample) * | 1975-08-13 | 1973-12-28 | Robins Co Inc A H |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2476071A1 (fr) * | 1980-02-19 | 1981-08-21 | Robins Co Inc A H | Nouveaux acides 2-amino-3-(a-hydroxybenzyl)-phenylacetiques et leurs esters et amides, utiles notamment comme agents anti-inflammatoires, et compositions pharmaceutiques les contenant |
| FR2499981A1 (fr) * | 1981-02-17 | 1982-08-20 | Robins Co Inc A H | Acides amino-2 halogenobenzoyl-3 methylphenylacetiques et leurs esters et sels utiles comme medicaments anti-inflammatoires et analgesiques |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2366015B1 (enExample) | 1979-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TP | Transmission of property |