FR2365345A2 - Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent - Google Patents

Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent

Info

Publication number
FR2365345A2
FR2365345A2 FR7628977A FR7628977A FR2365345A2 FR 2365345 A2 FR2365345 A2 FR 2365345A2 FR 7628977 A FR7628977 A FR 7628977A FR 7628977 A FR7628977 A FR 7628977A FR 2365345 A2 FR2365345 A2 FR 2365345A2
Authority
FR
France
Prior art keywords
daunorubicin
derivs
mouse
acyloxy
doses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7628977A
Other languages
English (en)
French (fr)
Other versions
FR2365345B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7628977A priority Critical patent/FR2365345A2/fr
Priority to NLAANVRAGE7612239,A priority patent/NL170737C/xx
Priority to CA265,119A priority patent/CA1072954A/en
Priority to SU762418213A priority patent/SU659095A3/ru
Priority to CS767234A priority patent/CS209876B2/cs
Priority to JP13510676A priority patent/JPS5285161A/ja
Priority to GB46807/76A priority patent/GB1525180A/en
Priority to NZ182591A priority patent/NZ182591A/xx
Priority to PH19114A priority patent/PH13709A/en
Priority to IE248476A priority patent/IE44076B1/en
Priority to AU19506/76A priority patent/AU504388B2/en
Priority to AR265428A priority patent/AR213419A1/es
Priority to IL50897A priority patent/IL50897A/xx
Priority to DK508776A priority patent/DK508776A/da
Priority to NO763857A priority patent/NO143349C/no
Priority to CH1423376A priority patent/CH606081A5/xx
Priority to SE7612613A priority patent/SE421212B/xx
Priority to LU76176A priority patent/LU76176A1/xx
Priority to HU76RO00000903A priority patent/HU172526B/hu
Priority to DE2651773A priority patent/DE2651773C3/de
Priority to ES453264A priority patent/ES453264A1/es
Priority to FI763251A priority patent/FI62316C/fi
Priority to YU02778/76A priority patent/YU277876A/xx
Priority to AT842876A priority patent/AT347583B/de
Priority to US05/849,761 priority patent/US4225589A/en
Publication of FR2365345A2 publication Critical patent/FR2365345A2/fr
Application granted granted Critical
Publication of FR2365345B2 publication Critical patent/FR2365345B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7628977A 1975-11-12 1976-09-27 Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent Granted FR2365345A2 (fr)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR7628977A FR2365345A2 (fr) 1976-09-27 1976-09-27 Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
NLAANVRAGE7612239,A NL170737C (nl) 1975-11-12 1976-11-04 Werkwijze voor het bereiden van tegen tumoren werkzame esters van adriamycine, alsmede voor het bereiden van geneesmiddelen met anti-tumoractiviteit.
CA265,119A CA1072954A (en) 1975-11-12 1976-11-08 Derivatives of daunorubicin; their preparation and compositions thereof
SU762418213A SU659095A3 (ru) 1975-11-12 1976-11-09 Способ получени производных даунорубицина или их солей
CS767234A CS209876B2 (en) 1975-11-12 1976-11-09 Method of preparation of the new daunorubicine derivatives
GB46807/76A GB1525180A (en) 1975-11-12 1976-11-10 Daunorubicin derivatives
NZ182591A NZ182591A (en) 1975-11-12 1976-11-10 14-substituted-daunorubicins and pharmaceutical compositions
PH19114A PH13709A (en) 1975-11-12 1976-11-10 Daunorubicin derivatives and pharmaceutical compositions containing same
IE248476A IE44076B1 (en) 1975-11-12 1976-11-10 Daunorubicin derivatives
AU19506/76A AU504388B2 (en) 1975-11-12 1976-11-10 Daunorubicin derivatives
JP13510676A JPS5285161A (en) 1975-11-12 1976-11-10 Daunorbicine derivatives
DK508776A DK508776A (da) 1975-11-12 1976-11-11 Fremgangsmade til fremstilling af derivater af daunorubicin eller syreadditionssalte deraf
AR265428A AR213419A1 (es) 1975-11-12 1976-11-11 Procedimiento para preparar nuevos derivados de daunorubicina
NO763857A NO143349C (no) 1975-11-12 1976-11-11 Analogifremgangsmaate for fremstilling av nye derivater av daunorubicin.
CH1423376A CH606081A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-11-12 1976-11-11
SE7612613A SE421212B (sv) 1975-11-12 1976-11-11 Forfarande for framstellning av nya derivat av daunorubicin
LU76176A LU76176A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-11-12 1976-11-11
HU76RO00000903A HU172526B (hu) 1975-11-12 1976-11-11 Sposob poluchenija novykh proizvodnykh davnorubicina
IL50897A IL50897A (en) 1975-11-12 1976-11-11 Daunorubicin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
DE2651773A DE2651773C3 (de) 1975-11-12 1976-11-12 14-Acyloxy-daunorubicine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
ES453264A ES453264A1 (es) 1975-11-12 1976-11-12 Procedimiento de preparacion de derivados de daunorublicina.
FI763251A FI62316C (fi) 1975-11-12 1976-11-12 Foerfarande foer framstaellning av di- eller trisubstituerade estrar av daunorubicinderivat vilka aer anvaendbara vid behandling av tumoerer
YU02778/76A YU277876A (en) 1975-11-12 1976-11-12 Process for obtaining new derivatives of daunorubicin
AT842876A AT347583B (de) 1975-11-12 1976-11-12 Verfahren zur herstellung von neuen daunoru- bicinderivaten und von deren saeureadditions- salzen
US05/849,761 US4225589A (en) 1975-11-12 1977-11-09 Daunorubicin derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7628977A FR2365345A2 (fr) 1976-09-27 1976-09-27 Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
FR2365345A2 true FR2365345A2 (fr) 1978-04-21
FR2365345B2 FR2365345B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-02-01

Family

ID=9178114

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7628977A Granted FR2365345A2 (fr) 1975-11-12 1976-09-27 Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent

Country Status (1)

Country Link
FR (1) FR2365345A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2434820A1 (fr) * 1978-08-29 1980-03-28 Inst Internal Pathologie Complexes d'adn et d'esters de derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2434820A1 (fr) * 1978-08-29 1980-03-28 Inst Internal Pathologie Complexes d'adn et d'esters de derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
FR2365345B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-02-01

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