FR2361412A1 - Systeme enzymatique scindant le fibrinogene - Google Patents
Systeme enzymatique scindant le fibrinogeneInfo
- Publication number
- FR2361412A1 FR2361412A1 FR7710776A FR7710776A FR2361412A1 FR 2361412 A1 FR2361412 A1 FR 2361412A1 FR 7710776 A FR7710776 A FR 7710776A FR 7710776 A FR7710776 A FR 7710776A FR 2361412 A1 FR2361412 A1 FR 2361412A1
- Authority
- FR
- France
- Prior art keywords
- enzymatic system
- fibrinogen
- fibrinogen split
- solution
- split
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000008946 Fibrinogen Human genes 0.000 title abstract 2
- 108010049003 Fibrinogen Proteins 0.000 title abstract 2
- 229940012952 fibrinogen Drugs 0.000 title abstract 2
- FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 title 1
- 230000002255 enzymatic effect Effects 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 210000005259 peripheral blood Anatomy 0.000 abstract 1
- 239000011886 peripheral blood Substances 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/75—Fibrin; Fibrinogen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- G01N2400/12—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
- G01N2400/14—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar alpha-D-Glucans, i.e. having alpha 1,n (n=3,4,6) linkages between saccharide units, e.g. pullulan
- G01N2400/22—Dextran
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
a. L'invention concerne un système enzymatique capable de scinder le fibrinogène. b. On augmente considérablement l'efficacité des fibrinogénases en ajoutant à leur solution une solution d'un polysaccharide hydrosoluble. c. La combinaison des deux produits peut être utilisée pour établir des diagnostics et pour traiter les troubles de la circulation sanguine périphérique.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19762615844 DE2615844A1 (de) | 1976-04-10 | 1976-04-10 | Fibrinogen spaltendes enzymsystem |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2361412A1 true FR2361412A1 (fr) | 1978-03-10 |
FR2361412B1 FR2361412B1 (fr) | 1980-04-04 |
Family
ID=5975094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7710776A Granted FR2361412A1 (fr) | 1976-04-10 | 1977-04-08 | Systeme enzymatique scindant le fibrinogene |
Country Status (11)
Country | Link |
---|---|
US (1) | US4154656A (fr) |
JP (1) | JPS52125689A (fr) |
AT (1) | AT353423B (fr) |
BE (1) | BE852758A (fr) |
DE (1) | DE2615844A1 (fr) |
DK (1) | DK158677A (fr) |
FR (1) | FR2361412A1 (fr) |
GB (1) | GB1519285A (fr) |
IE (1) | IE44735B1 (fr) |
LU (1) | LU77089A1 (fr) |
NL (1) | NL7703444A (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3330699A1 (de) * | 1983-08-25 | 1985-03-07 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur gleichzeitigen bestimmung von fibrinogen und fibrinogen-spaltprodukten im plasma |
DE3841736A1 (de) * | 1988-12-10 | 1990-07-05 | Basf Ag | Ancrod-proteine, ihre herstellung und verwendung |
ES2386972T3 (es) * | 2006-05-31 | 2012-09-10 | Genzyme Corporation | Uso de polisacáridos para la estimulación de la actividad enzimática |
US8178145B1 (en) | 2007-11-14 | 2012-05-15 | JMC Enterprises, Inc. | Methods and systems for applying sprout inhibitors and/or other substances to harvested potatoes and/or other vegetables in storage facilities |
US9605890B2 (en) | 2010-06-30 | 2017-03-28 | Jmc Ventilation/Refrigeration, Llc | Reverse cycle defrost method and apparatus |
US10076129B1 (en) | 2016-07-15 | 2018-09-18 | JMC Enterprises, Inc. | Systems and methods for inhibiting spoilage of stored crops |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH586233A5 (fr) * | 1971-01-18 | 1977-03-31 | Pentapharm Ag | |
GB1479268A (en) * | 1973-07-05 | 1977-07-13 | Beecham Group Ltd | Pharmaceutical compositions |
US3819605A (en) * | 1973-08-17 | 1974-06-25 | Abbott Lab | Anticoagulant isolation from pit viper using a modified agarose bed and eluting with a benzamidine solution |
GB1472574A (en) * | 1973-09-03 | 1977-05-04 | Biochimici Fargal Pharmasint S | Process for the extraction of components having anticoagulant activity -in vivo- from snake venoms and related products |
US3985618A (en) * | 1975-05-02 | 1976-10-12 | Irving Innerfield | Method for detection of thrombosis and prethrombosis |
-
1976
- 1976-04-10 DE DE19762615844 patent/DE2615844A1/de active Pending
-
1977
- 1977-03-15 GB GB10809/77A patent/GB1519285A/en not_active Expired
- 1977-03-21 US US05/779,584 patent/US4154656A/en not_active Expired - Lifetime
- 1977-03-22 BE BE176018A patent/BE852758A/fr unknown
- 1977-03-30 NL NL7703444A patent/NL7703444A/xx not_active Application Discontinuation
- 1977-04-05 IE IE720/77A patent/IE44735B1/en unknown
- 1977-04-06 DK DK158677A patent/DK158677A/da not_active IP Right Cessation
- 1977-04-07 AT AT244877A patent/AT353423B/de not_active IP Right Cessation
- 1977-04-08 FR FR7710776A patent/FR2361412A1/fr active Granted
- 1977-04-08 LU LU77089A patent/LU77089A1/xx unknown
- 1977-04-11 JP JP4128577A patent/JPS52125689A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US4154656A (en) | 1979-05-15 |
AT353423B (de) | 1979-11-12 |
FR2361412B1 (fr) | 1980-04-04 |
DK158677A (da) | 1977-10-11 |
DE2615844A1 (de) | 1977-10-20 |
JPS52125689A (en) | 1977-10-21 |
ATA244877A (de) | 1979-04-15 |
IE44735B1 (en) | 1982-03-10 |
GB1519285A (en) | 1978-07-26 |
NL7703444A (nl) | 1977-10-12 |
BE852758A (fr) | 1977-09-22 |
LU77089A1 (fr) | 1977-08-10 |
IE44735L (en) | 1977-10-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |