FR2361347A1 - Procede pour enlever des groupements protegeant les groupes thiol presents dans des amino-acides et des peptides - Google Patents

Procede pour enlever des groupements protegeant les groupes thiol presents dans des amino-acides et des peptides

Info

Publication number
FR2361347A1
FR2361347A1 FR7719632A FR7719632A FR2361347A1 FR 2361347 A1 FR2361347 A1 FR 2361347A1 FR 7719632 A FR7719632 A FR 7719632A FR 7719632 A FR7719632 A FR 7719632A FR 2361347 A1 FR2361347 A1 FR 2361347A1
Authority
FR
France
Prior art keywords
groups
peptides
amino acids
protecting
thiol groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7719632A
Other languages
English (en)
French (fr)
Other versions
FR2361347B1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FR2361347A1 publication Critical patent/FR2361347A1/fr
Application granted granted Critical
Publication of FR2361347B1 publication Critical patent/FR2361347B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7719632A 1976-06-28 1977-06-27 Procede pour enlever des groupements protegeant les groupes thiol presents dans des amino-acides et des peptides Granted FR2361347A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51076676A JPS5848524B2 (ja) 1976-06-28 1976-06-28 チオ−ル保護基の脱離方法

Publications (2)

Publication Number Publication Date
FR2361347A1 true FR2361347A1 (fr) 1978-03-10
FR2361347B1 FR2361347B1 (enExample) 1980-10-17

Family

ID=13612020

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7719632A Granted FR2361347A1 (fr) 1976-06-28 1977-06-27 Procede pour enlever des groupements protegeant les groupes thiol presents dans des amino-acides et des peptides

Country Status (5)

Country Link
JP (1) JPS5848524B2 (enExample)
CA (1) CA1074300A (enExample)
FR (1) FR2361347A1 (enExample)
GB (1) GB1548101A (enExample)
HU (1) HU178756B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2451915A1 (fr) * 1979-03-23 1980-10-17 Clin Midy Nouveau procede de preparation de la somatostatine

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62227054A (ja) * 1986-03-28 1987-10-06 Sumitomo Special Metals Co Ltd 加工性のすぐれた高透磁率磁性合金
JPS62227053A (ja) * 1986-03-28 1987-10-06 Sumitomo Special Metals Co Ltd 加工性のすぐれた高透磁率磁性合金
JPH02111838A (ja) * 1988-10-21 1990-04-24 Nippon Steel Corp 熱間加工性及び磁気特性に優れたＦｅ−Ｎｉ系磁性合金
JPH04214832A (ja) * 1990-07-30 1992-08-05 Nippon Yakin Kogyo Co Ltd メッキ性ならびにハンダ付け性に優れる電子材料用Ｆｅ―高Ｎｉ系合金

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2451915A1 (fr) * 1979-03-23 1980-10-17 Clin Midy Nouveau procede de preparation de la somatostatine
EP0017536A3 (en) * 1979-03-23 1981-01-07 Sanofi, Societe Anonyme Process for the preparation of somatostatine, the intermediates and their preparation

Also Published As

Publication number Publication date
JPS5848524B2 (ja) 1983-10-28
FR2361347B1 (enExample) 1980-10-17
HU178756B (en) 1982-06-28
GB1548101A (en) 1979-07-04
CA1074300A (en) 1980-03-25
JPS532404A (en) 1978-01-11

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Legal Events

Date Code Title Description
ST Notification of lapse