FR2359149A1 - PROCESS FOR THE PREPARATION OF A NEW ALKALOID OF THE VINCAMINE TYPE AND OF THE SALTS OF THIS ALKALOID - Google Patents

PROCESS FOR THE PREPARATION OF A NEW ALKALOID OF THE VINCAMINE TYPE AND OF THE SALTS OF THIS ALKALOID

Info

Publication number
FR2359149A1
FR2359149A1 FR7722309A FR7722309A FR2359149A1 FR 2359149 A1 FR2359149 A1 FR 2359149A1 FR 7722309 A FR7722309 A FR 7722309A FR 7722309 A FR7722309 A FR 7722309A FR 2359149 A1 FR2359149 A1 FR 2359149A1
Authority
FR
France
Prior art keywords
alkaloid
vincamine
new
type
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7722309A
Other languages
French (fr)
Other versions
FR2359149B1 (en
Inventor
Otto Clauder
Arpad Kiraly
Joszef Kokosi
Egon Karpati
Laszlo Szporny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Nyrt
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Nyrt
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt, Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Nyrt
Publication of FR2359149A1 publication Critical patent/FR2359149A1/en
Application granted granted Critical
Publication of FR2359149B1 publication Critical patent/FR2359149B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Abstract

The new alkaloid of the vincamine type of the formula and addition salts thereof are prepared. The new compound is obtained by subjecting either vincamic acid to dehydration and decarboxylation or by decarboxylating apovincamic acid. The compound obtained is converted into quaternary ammonium salts.
FR7722309A 1976-07-21 1977-07-20 PROCESS FOR THE PREPARATION OF A NEW ALKALOID OF THE VINCAMINE TYPE AND OF THE SALTS OF THIS ALKALOID Granted FR2359149A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76RI593A HU173511B (en) 1976-07-21 1976-07-21 Process for preparing vincamenine further salts and molecular compounds thereof

Publications (2)

Publication Number Publication Date
FR2359149A1 true FR2359149A1 (en) 1978-02-17
FR2359149B1 FR2359149B1 (en) 1982-06-11

Family

ID=11000999

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7722309A Granted FR2359149A1 (en) 1976-07-21 1977-07-20 PROCESS FOR THE PREPARATION OF A NEW ALKALOID OF THE VINCAMINE TYPE AND OF THE SALTS OF THIS ALKALOID

Country Status (14)

Country Link
JP (1) JPS5331700A (en)
AT (1) AT354646B (en)
BE (1) BE856990A (en)
BG (1) BG29875A3 (en)
CH (2) CH629803A5 (en)
CS (1) CS196378B2 (en)
DD (1) DD131024A5 (en)
DE (1) DE2733056C2 (en)
FR (1) FR2359149A1 (en)
HU (1) HU173511B (en)
NL (1) NL7708056A (en)
SE (1) SE7708250L (en)
SU (2) SU719507A3 (en)
YU (1) YU180177A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2514357A1 (en) * 1981-10-08 1983-04-15 Roussel Uclaf NOVEL 20,21-DINOREBURNAMENINE DERIVATIVES POSSIBLY SUBSTITUTED ON CYCLE E, PREPARATION METHOD AND APPLICATION AS MEDICAMENTS
LU84664A1 (en) * 1983-02-25 1984-11-08 Onmichem S A ALKYL-4-INDOLONAPHTYRIDINES AND THEIR THERAPEUTIC APPLICATION

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2151882A5 (en) * 1971-08-31 1973-04-20 Omnium Chimique Sa Vincanols - with circulatory activity from delta-1-aspidospermidine
NL7510315A (en) * 1974-09-06 1976-03-09 Sandoz Ag PROCESS FOR PREPARING NEW ORGANIC COMPOUNDS.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2151882A5 (en) * 1971-08-31 1973-04-20 Omnium Chimique Sa Vincanols - with circulatory activity from delta-1-aspidospermidine
NL7510315A (en) * 1974-09-06 1976-03-09 Sandoz Ag PROCESS FOR PREPARING NEW ORGANIC COMPOUNDS.
FR2342065A1 (en) * 1974-09-06 1977-09-23 Sandoz Sa NEW HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EXBK/60 *
EXBK/61 *

Also Published As

Publication number Publication date
AT354646B (en) 1979-01-25
YU180177A (en) 1982-08-31
ATA474177A (en) 1979-06-15
FR2359149B1 (en) 1982-06-11
HU173511B (en) 1979-05-28
SU719507A3 (en) 1980-02-29
DD131024A5 (en) 1978-05-24
DE2733056C2 (en) 1982-08-12
CS196378B2 (en) 1980-03-31
NL7708056A (en) 1978-01-24
CH629803A5 (en) 1982-05-14
SU862827A3 (en) 1981-09-07
JPS5526142B2 (en) 1980-07-11
DE2733056A1 (en) 1978-01-26
BE856990A (en) 1977-11-14
BG29875A3 (en) 1981-02-16
CH631175A5 (en) 1982-07-30
JPS5331700A (en) 1978-03-25
SE7708250L (en) 1978-01-22

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Legal Events

Date Code Title Description
ST Notification of lapse