FR2358881A1 - Composition pharmaceutique active sur le systeme nerveux central - Google Patents
Composition pharmaceutique active sur le systeme nerveux centralInfo
- Publication number
- FR2358881A1 FR2358881A1 FR7622045A FR7622045A FR2358881A1 FR 2358881 A1 FR2358881 A1 FR 2358881A1 FR 7622045 A FR7622045 A FR 7622045A FR 7622045 A FR7622045 A FR 7622045A FR 2358881 A1 FR2358881 A1 FR 2358881A1
- Authority
- FR
- France
- Prior art keywords
- neuroleptic
- schizophrenia
- compsn
- treating
- gabamimetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003176 neuroleptic agent Substances 0.000 title abstract 2
- 230000000701 neuroleptic effect Effects 0.000 title abstract 2
- 201000000980 schizophrenia Diseases 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- ZPEIMTDSQAKGNT-UHFFFAOYSA-N chlorpromazine Chemical compound C1=C(Cl)C=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 0.000 abstract 2
- 229960001076 chlorpromazine Drugs 0.000 abstract 2
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- OGNSCSPNOLGXSM-UHFFFAOYSA-N (+/-)-DABA Natural products NCCC(N)C(O)=O OGNSCSPNOLGXSM-UHFFFAOYSA-N 0.000 abstract 1
- CVICEEPAFUYBJG-UHFFFAOYSA-N 5-chloro-2,2-difluoro-1,3-benzodioxole Chemical group C1=C(Cl)C=C2OC(F)(F)OC2=C1 CVICEEPAFUYBJG-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229960003692 gamma aminobutyric acid Drugs 0.000 abstract 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
- 101150009274 nhr-1 gene Proteins 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7622045A FR2358881A1 (fr) | 1976-07-20 | 1976-07-20 | Composition pharmaceutique active sur le systeme nerveux central |
NZ184666A NZ184666A (en) | 1976-07-20 | 1977-07-18 | Pharmaceutical compositions comprising a gabamimetic compound and a neuroleptic compound |
IL52550A IL52550A (en) | 1976-07-20 | 1977-07-18 | Pharmaceutical compositions having an action on the central nervous system coprising a gabamimetic compound and a neuroleptic compound |
AU27151/77A AU508753B2 (en) | 1976-07-20 | 1977-07-19 | Central nervous system pharmaceuticals |
CA283,049A CA1077846A (en) | 1976-07-20 | 1977-07-19 | Pharmaceutical compositions having an action on the central nervous system |
LU77796A LU77796A1 (enrdf_load_stackoverflow) | 1976-07-20 | 1977-07-19 | |
IE1509/77A IE45454B1 (en) | 1976-07-20 | 1977-07-19 | Pharmaceutical compositions having an action on the central nervous system |
GB30355/77A GB1556567A (en) | 1976-07-20 | 1977-07-19 | Pharmaceutical compositions having an action on the central nervous system |
BE179459A BE856937A (fr) | 1976-07-20 | 1977-07-19 | Compositions pharmaceutiques actives sur le systeme nerveux central |
DE19772732614 DE2732614A1 (de) | 1976-07-20 | 1977-07-19 | Arzneimittel mit wirkung auf das zentralnervensystem |
SE7708349A SE7708349L (sv) | 1976-07-20 | 1977-07-19 | Farmaceutiska kompositioner och forfarande for framstellning derav |
JP8785277A JPS5326327A (en) | 1976-07-20 | 1977-07-20 | Medical composition active to central nerve system |
ZA00774376A ZA774376B (en) | 1976-07-20 | 1977-07-20 | Pharmaceutical compositions having an action on the central nervous system |
NL7708055A NL7708055A (nl) | 1976-07-20 | 1977-07-20 | Werkwijze voor het bereiden van een geneesmid- del en zo gevormd geneesmiddel. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7622045A FR2358881A1 (fr) | 1976-07-20 | 1976-07-20 | Composition pharmaceutique active sur le systeme nerveux central |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2358881A1 true FR2358881A1 (fr) | 1978-02-17 |
FR2358881B1 FR2358881B1 (enrdf_load_stackoverflow) | 1980-10-03 |
Family
ID=9175888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7622045A Granted FR2358881A1 (fr) | 1976-07-20 | 1976-07-20 | Composition pharmaceutique active sur le systeme nerveux central |
Country Status (3)
Country | Link |
---|---|
BE (1) | BE856937A (enrdf_load_stackoverflow) |
FR (1) | FR2358881A1 (enrdf_load_stackoverflow) |
ZA (1) | ZA774376B (enrdf_load_stackoverflow) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992018127A1 (en) * | 1991-04-15 | 1992-10-29 | The Du Pont Merck Pharmaceutical Company | Use of sigma receptor antagonists to enhance the effects of antipsychotic drugs |
-
1976
- 1976-07-20 FR FR7622045A patent/FR2358881A1/fr active Granted
-
1977
- 1977-07-19 BE BE179459A patent/BE856937A/xx not_active IP Right Cessation
- 1977-07-20 ZA ZA00774376A patent/ZA774376B/xx unknown
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992018127A1 (en) * | 1991-04-15 | 1992-10-29 | The Du Pont Merck Pharmaceutical Company | Use of sigma receptor antagonists to enhance the effects of antipsychotic drugs |
US5231099A (en) * | 1991-04-15 | 1993-07-27 | Du Pont Merck Pharmaceutical Company | Use of sigma receptor antagonists to enhance the effects of antipsychotic drugs |
Also Published As
Publication number | Publication date |
---|---|
BE856937A (fr) | 1978-01-19 |
ZA774376B (en) | 1978-06-28 |
FR2358881B1 (enrdf_load_stackoverflow) | 1980-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |