FR2358414A1 - Derives peptidiques, leur preparation et leur application comme agents antibacteriens - Google Patents

Derives peptidiques, leur preparation et leur application comme agents antibacteriens

Info

Publication number
FR2358414A1
FR2358414A1 FR7721280A FR7721280A FR2358414A1 FR 2358414 A1 FR2358414 A1 FR 2358414A1 FR 7721280 A FR7721280 A FR 7721280A FR 7721280 A FR7721280 A FR 7721280A FR 2358414 A1 FR2358414 A1 FR 2358414A1
Authority
FR
France
Prior art keywords
phosphonic acid
antibacterial
activity against
gram positive
against gram
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7721280A
Other languages
English (en)
Other versions
FR2358414B1 (fr
Inventor
Frank Ratcliffe Atherton
Michael John Hall
Cedric Herbert Hassall
Robert Wilson Lambert
Peter Stuart Ringrose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2358414A1 publication Critical patent/FR2358414A1/fr
Application granted granted Critical
Publication of FR2358414B1 publication Critical patent/FR2358414B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés chimiques nouveaux, un procédé pour leur préparation, et des préparations pharmaceutiques les contenant. Les nouveaux composés sont des dérivés peptidiques de formule générale :
FR7721280A 1976-07-13 1977-07-11 Derives peptidiques, leur preparation et leur application comme agents antibacteriens Granted FR2358414A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2910176 1976-07-13

Publications (2)

Publication Number Publication Date
FR2358414A1 true FR2358414A1 (fr) 1978-02-10
FR2358414B1 FR2358414B1 (fr) 1979-06-01

Family

ID=10286172

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7721280A Granted FR2358414A1 (fr) 1976-07-13 1977-07-11 Derives peptidiques, leur preparation et leur application comme agents antibacteriens

Country Status (13)

Country Link
JP (1) JPS539720A (fr)
AU (1) AU2684777A (fr)
BE (1) BE856724A (fr)
DE (1) DE2730524A1 (fr)
DK (1) DK317177A (fr)
FR (1) FR2358414A1 (fr)
IL (1) IL52469A0 (fr)
IT (1) IT1081511B (fr)
LU (1) LU77725A1 (fr)
NL (1) NL7707736A (fr)
NZ (1) NZ184603A (fr)
SE (1) SE7708120L (fr)
ZA (1) ZA774073B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0014834A1 (fr) * 1979-01-18 1980-09-03 Hoechst Aktiengesellschaft Procédé de préparation d'amides d'acides carboxyliques et de peptides
EP1585751A2 (fr) * 2002-11-14 2005-10-19 Celmed Oncology (USA), Inc. Promedicaments actives par peptide deformylase

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR73085B (fr) * 1977-12-20 1984-01-31 Hoffmann La Roche
CA1108125A (fr) * 1977-12-23 1981-09-01 Frank R. Atherton Derives oligopeptides de l'acide phosphonique
EP0103867B1 (fr) * 1982-09-17 1986-12-17 Kyowa Hakko Kogyo Co., Ltd. Dérivé de peptide contenant du phosphore

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2298335A1 (fr) * 1975-01-27 1976-08-20 Hoffmann La Roche Nouveaux derives de peptides d'acides phosphonique et phosphinique

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2298335A1 (fr) * 1975-01-27 1976-08-20 Hoffmann La Roche Nouveaux derives de peptides d'acides phosphonique et phosphinique

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0014834A1 (fr) * 1979-01-18 1980-09-03 Hoechst Aktiengesellschaft Procédé de préparation d'amides d'acides carboxyliques et de peptides
EP1585751A2 (fr) * 2002-11-14 2005-10-19 Celmed Oncology (USA), Inc. Promedicaments actives par peptide deformylase
EP1585751A4 (fr) * 2002-11-14 2008-08-13 Celmed Oncology Usa Inc Promedicaments actives par peptide deformylase

Also Published As

Publication number Publication date
LU77725A1 (fr) 1978-09-14
BE856724A (fr) 1978-01-12
ZA774073B (en) 1978-05-30
SE7708120L (sv) 1978-01-14
DE2730524A1 (de) 1978-01-19
NZ184603A (en) 1980-03-05
IL52469A0 (en) 1977-10-31
DK317177A (da) 1978-01-14
IT1081511B (it) 1985-05-21
AU2684777A (en) 1979-01-11
FR2358414B1 (fr) 1979-06-01
JPS539720A (en) 1978-01-28
NL7707736A (nl) 1978-01-17

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Legal Events

Date Code Title Description
ST Notification of lapse