ES8100250A1 - Un procedimiento para la preparacion de un peptido - Google Patents

Un procedimiento para la preparacion de un peptido

Info

Publication number
ES8100250A1
ES8100250A1 ES485269A ES485269A ES8100250A1 ES 8100250 A1 ES8100250 A1 ES 8100250A1 ES 485269 A ES485269 A ES 485269A ES 485269 A ES485269 A ES 485269A ES 8100250 A1 ES8100250 A1 ES 8100250A1
Authority
ES
Spain
Prior art keywords
antibacterial peptide
antibacterials
alanine
terminus
antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES485269A
Other languages
English (en)
Other versions
ES485269A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of ES485269A0 publication Critical patent/ES485269A0/es
Publication of ES8100250A1 publication Critical patent/ES8100250A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE PEPTIDOS. CONSISTE EN COPULAR LA -FALOGENOD-ALAMINA (SIENDO EL HALOGENO FLUOR O CLORO) CON UN ESTER ACTIVO DE GLICINA O UN AMINOACIDO EN LA CONFIGURACION-L. SE OBTIENE UN COMPUESTO DE FORMULA GENERAL (I). SI ESTA PRESENTE EL GRUPO PROTECTOR N SE SEPARA Y SI SE DESEA SE ESTERIFICA EL GRUPO CARBOXI CON UN ALCOHOL ALQUILO INFERIOR. AGENTES ANTIBACTERIANOS.
ES485269A 1978-10-23 1979-10-22 Un procedimiento para la preparacion de un peptido Expired ES8100250A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95351678A 1978-10-23 1978-10-23
US4167979A 1979-05-23 1979-05-23

Publications (2)

Publication Number Publication Date
ES485269A0 ES485269A0 (es) 1980-11-01
ES8100250A1 true ES8100250A1 (es) 1980-11-01

Family

ID=26718400

Family Applications (1)

Application Number Title Priority Date Filing Date
ES485269A Expired ES8100250A1 (es) 1978-10-23 1979-10-22 Un procedimiento para la preparacion de un peptido

Country Status (14)

Country Link
EP (1) EP0020481A4 (es)
JP (1) JPS55500821A (es)
AR (1) AR229015A1 (es)
AU (1) AU528165B2 (es)
CA (1) CA1137468A (es)
DK (1) DK208680A (es)
ES (1) ES8100250A1 (es)
GR (1) GR73145B (es)
IL (1) IL58487A (es)
IT (1) IT1125557B (es)
NZ (1) NZ191839A (es)
PH (1) PH14917A (es)
PT (1) PT70319A (es)
WO (1) WO1980000789A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984002905A1 (en) * 1983-01-26 1984-08-02 University Patents Inc Antibacterial peptides
AU742278B2 (en) * 1996-10-29 2001-12-20 Graeme Smith A stump
US20040052928A1 (en) 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
US7491699B2 (en) 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
ATE426575T1 (de) 2003-01-07 2009-04-15 Univ Ramot Peptidenanostrukturen die fremdmaterial enthalten,und verfahren zur herstellung derselben
ES2597377T3 (es) 2003-04-03 2017-01-18 Galil Medical Ltd Aparato para crioablación delimitada con precisión
EP2719394B1 (en) 2003-06-30 2015-07-29 Tel Aviv University Future Technology Development L.P. Peptides for treating amyloid-associated diseases
WO2005027901A1 (en) 2003-09-25 2005-03-31 Tel Aviv University Future Technology Development L.P. Compositions and methods using same for treating amyloid-associated diseases
US20090156471A1 (en) * 2004-07-15 2009-06-18 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
US8568637B2 (en) 2004-08-02 2013-10-29 Ramot At Tel-Aviv University Ltd. Method of forming a fiber made of peptide nanostructures
EP1793816B1 (en) 2004-08-19 2012-01-04 Tel Aviv University Future Technology Development L.P. Compositions for treating amyloid associated diseases
WO2006027780A2 (en) 2004-09-08 2006-03-16 Ramot At Tel Aviv University Ltd. Peptide nanostructures containing end-capping modified peptides and methods of generating and using the same
EP1973928A2 (en) 2005-10-11 2008-10-01 Ramot at Tel-Aviv University Ltd. Self-assembled fmoc-ff hydrogels
MX2013005413A (es) 2010-11-15 2014-02-27 Univ Ramot Analogos de dipeptidos para el tratamiento de afecciones asociadas con la formacion de fibrillas amiloides.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3956367A (en) * 1972-02-03 1976-05-11 Merck & Co., Inc. 3-Fluoro-D-alanine and pharmacologically acceptable esters, and pharmacologically acceptable salts thereof
US4031231A (en) * 1974-06-13 1977-06-21 Merck & Co., Inc. Antibacterial composition comprising 3-fluoro-D-alanine or deutero analog in combination with auto-antagonist inhibitor
US4028405A (en) * 1974-10-15 1977-06-07 Merck & Co., Inc. Fluorinated amino acids

Also Published As

Publication number Publication date
EP0020481A1 (en) 1981-01-07
DK208680A (da) 1980-05-13
AU528165B2 (en) 1983-04-14
ES485269A0 (es) 1980-11-01
AR229015A1 (es) 1983-05-31
AU5204079A (en) 1980-05-01
CA1137468A (en) 1982-12-14
PT70319A (en) 1979-11-01
JPS55500821A (es) 1980-10-23
WO1980000789A1 (en) 1980-05-01
GR73145B (es) 1984-02-09
NZ191839A (en) 1983-02-15
IT1125557B (it) 1986-05-14
EP0020481A4 (en) 1981-04-24
PH14917A (en) 1982-01-29
IL58487A (en) 1982-09-30
IT7926703A0 (it) 1979-10-22
IL58487A0 (en) 1980-01-31

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