FR2356927A1 - Nouveau dispositif intermediaire a employer dans un ensemble combine de chromatographie en phase liquide et de spectrometrie de masse - Google Patents

Nouveau dispositif intermediaire a employer dans un ensemble combine de chromatographie en phase liquide et de spectrometrie de masse

Info

Publication number
FR2356927A1
FR2356927A1 FR7718830A FR7718830A FR2356927A1 FR 2356927 A1 FR2356927 A1 FR 2356927A1 FR 7718830 A FR7718830 A FR 7718830A FR 7718830 A FR7718830 A FR 7718830A FR 2356927 A1 FR2356927 A1 FR 2356927A1
Authority
FR
France
Prior art keywords
intermediate device
mass spectrometry
liquid phase
phase chromatography
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7718830A
Other languages
English (en)
Other versions
FR2356927B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Publication of FR2356927A1 publication Critical patent/FR2356927A1/fr
Application granted granted Critical
Publication of FR2356927B1 publication Critical patent/FR2356927B1/fr
Granted legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G01N30/7246—Nebulising, aerosol formation or ionisation by pneumatic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/728—Intermediate storage of effluent, including condensation on surface
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

Dispositif intermédiaire utilisable dans un ensemble combiné de chromatographie en phase liquide et de spectrométrie de masse qui extrait un composant echantillon de l'effluent comprenant un composant échantillon et un composant solvant qui sort d'un chromatographe en phase liquide et introduit le composant échantillon extrait dans un spectromètre de masse, caractérisé en ce que ce dispositif intermédiaire est constitué d'un premier dispositif de nébulisation de l'effluent du chromatographe en phase liquide et de chauffage de cet effluent de façon à vaporiser uniquement le composant solvant et d'un second dispositif de séparation du composant échantillon nébulisé et du composant solvant vaporise qui extrait et applique uniquement le composant échantillon nébulisé au spectromètre de masse.
FR7718830A 1976-06-30 1977-06-20 Nouveau dispositif intermediaire a employer dans un ensemble combine de chromatographie en phase liquide et de spectrometrie de masse Granted FR2356927A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51076362A JPS5843692B2 (ja) 1976-06-30 1976-06-30 液体クロマトグラフと質量分析計とを結合した分析装置

Publications (2)

Publication Number Publication Date
FR2356927A1 true FR2356927A1 (fr) 1978-01-27
FR2356927B1 FR2356927B1 (fr) 1979-03-09

Family

ID=13603236

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7718830A Granted FR2356927A1 (fr) 1976-06-30 1977-06-20 Nouveau dispositif intermediaire a employer dans un ensemble combine de chromatographie en phase liquide et de spectrometrie de masse

Country Status (5)

Country Link
US (1) US4112297A (fr)
JP (1) JPS5843692B2 (fr)
DE (1) DE2728944C3 (fr)
FR (1) FR2356927A1 (fr)
GB (1) GB1524759A (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2457562A1 (fr) * 1979-05-25 1980-12-19 Hewlett Packard Co Appareil permettant d'analyser des echantillons de liquide au moyen d'un spectrometre de masse
WO1993017320A1 (fr) * 1992-02-19 1993-09-02 Fisons Plc Chambre d'evaporation et nebulisateur d'echantillon pour spectrometre a emission de plasma a couplage inductif (icp) et de plasma a induction micro-onde (mip) ou de masse et spectrometres les contenant
ES2109159A1 (es) * 1995-04-26 1998-01-01 Univ Alicante Sistema de desolvatacion por microondas para uso en espectrometria atomica.

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS583592B2 (ja) * 1978-09-08 1983-01-21 日本分光工業株式会社 質量分析計への試料導入方法及び装置
US4281246A (en) * 1979-10-12 1981-07-28 The United States Of America As Represented By The Administrator Of The United States Environmental Protection Agency Continuous-flow solution concentrator and liquid chromatograph/mass spectrometer interface and methods for using both
US4391778A (en) * 1981-09-30 1983-07-05 The Ohio State University Method and apparatus for the analysis of materials by chromatography and mass spectrometry
JPS5991360A (ja) * 1982-11-17 1984-05-26 Hitachi Ltd 液体クロマトグラフと質量分析計とを結合した分析装置
US4517461A (en) * 1982-11-29 1985-05-14 Phillips Petroleum Co Carbon isotope analysis of hydrocarbons
US4861989A (en) * 1983-08-30 1989-08-29 Research Corporation Technologies, Inc. Ion vapor source for mass spectrometry of liquids
US4814612A (en) * 1983-08-30 1989-03-21 Research Corporation Method and means for vaporizing liquids for detection or analysis
US4960992A (en) * 1983-08-30 1990-10-02 Research Corporation Technologies Method and means for vaporizing liquids by means of heating a sample capillary tube for detection or analysis
JPS59210358A (ja) * 1984-04-27 1984-11-29 Hitachi Ltd 液体クロマトグラフ−大気圧イオン化質量分析計結合分析装置
US4762995A (en) * 1984-06-22 1988-08-09 Georgia Tech Research Corporation Monodisperse aerosol generator
US4924097A (en) * 1984-06-22 1990-05-08 Georgia Tech Rss. Corp Monodisperse aerosol generator for use with infrared spectrometry
US4629478A (en) * 1984-06-22 1986-12-16 Georgia Tech Research Corporation Monodisperse aerosol generator
US4687929A (en) * 1984-06-22 1987-08-18 Georgia Tech Research Corporation Monodisperse aerosol generator
GB2205196B (en) * 1987-05-19 1991-04-24 Jeol Ltd Ion source for a mass spectrometer
US4863491A (en) * 1988-05-27 1989-09-05 Hewlett-Packard Interface for liquid chromatography-mass spectrometry systems
US4883958A (en) * 1988-12-16 1989-11-28 Vestec Corporation Interface for coupling liquid chromatography to solid or gas phase detectors
JP2892795B2 (ja) * 1989-09-12 1999-05-17 エーザイ株式会社 高速液体クロマトグラフィー質量分析における移動相の変換方法と装置
US4980057A (en) * 1989-10-03 1990-12-25 General Electric Company Apparatus for mass spectrometric analysis of liquid chromatographic fractions
US4958529A (en) * 1989-11-22 1990-09-25 Vestec Corporation Interface for coupling liquid chromatography to solid or gas phase detectors
US5083450A (en) * 1990-05-18 1992-01-28 Martin Marietta Energy Systems, Inc. Gas chromatograph-mass spectrometer (gc/ms) system for quantitative analysis of reactive chemical compounds
DE69120935T2 (de) * 1990-08-09 1996-12-12 Fisons Plc, Ipswich, Suffolk Verfahren und vorrichtung zur vorbereitung analytischer proben
US5266192A (en) * 1991-09-12 1993-11-30 General Electric Company Apparatus for interfacing liquid chromatograph with magnetic sector spectrometer
US5238653A (en) * 1991-10-15 1993-08-24 Bio-Rad Laboratories, Inc. Sample concentrator/solvent exchange system
JP2774774B2 (ja) * 1994-06-14 1998-07-09 東京都 高速液体クロマトグラフィーと質量分析計を組み合わせた定量分析装置、およびその試料イオン化用コロナ放電電極針
US5480809A (en) * 1994-07-27 1996-01-02 Mcgill University Method and apparatus for removal of residual interfering nebulized sample
US6126086A (en) * 1995-01-10 2000-10-03 Georgia Tech Research Corp. Oscillating capillary nebulizer with electrospray
US5725153A (en) * 1995-01-10 1998-03-10 Georgia Tech Research Corporation Oscillating capillary nebulizer
US5719062A (en) * 1995-06-06 1998-02-17 Saint Gobain Industrial Ceramics Corporation Process for analyzing analytes using HF-resistant ultrasonic nebulizer components
DE29605650U1 (de) * 1996-03-27 1996-07-25 Balzers Prozess Systeme Vertriebs- und Service GmbH, 81245 München Anordnung zum Verbinden eines Tiefdruckeinganges eines Gasanalysegerätes
JP4590091B2 (ja) * 2000-11-24 2010-12-01 大陽日酸株式会社 ガス分析装置
US6902937B2 (en) * 2001-07-13 2005-06-07 Air Liquide America, L.P. Method for the determination of low-concentration anions in the presence of an excess of another anion
DE10216975B4 (de) * 2002-04-16 2007-10-18 Thermo Electron (Bremen) Gmbh Verfahren und Vorrichtung zur Bereitstellung von Gas für die Isotopenverhältnisanalyse
DE102005018523B3 (de) * 2005-04-20 2006-08-24 Institut für Ostseeforschung Warnemünde Verfahren und Vorrichtung zum Austreiben von Gasen und leichtflüchtigen Substanzen aus Wasser nach dem Purge-and-Trap Verfahren
JP2008139130A (ja) * 2006-12-01 2008-06-19 Hitachi Ltd リアルタイム分析装置及び方法
WO2008073361A1 (fr) * 2006-12-08 2008-06-19 Spectra Analysis, Inc. Procédé et appareil permettant de désolvater un liquide en circulation
JP4925191B2 (ja) * 2007-02-23 2012-04-25 株式会社シマノ 釣り竿
CN103630640B (zh) 2007-12-05 2016-08-17 全技术联合公司 用于分析样本和收集样本流份的方法和装置
EP2113770B1 (fr) * 2008-04-30 2012-02-01 Symrise AG Dispositif et procédé de réduction d'une teneur en éthanol d'une préparation liquide
JP2012511725A (ja) 2008-12-10 2012-05-24 オールテック・アソシエイツ・インコーポレーテッド クロマトグラフィーシステムおよびシステム部品
US9470664B2 (en) 2009-04-10 2016-10-18 Waters Technologies Corporation Chromatographic interface
US8314934B2 (en) 2009-09-01 2012-11-20 Alltech Associates, Inc. Methods and apparatus for analyzing samples and collecting sample fractions
GB2519395B (en) * 2013-07-11 2015-09-16 Waters Technologies Corp Chromatographic interface
EP3084422A4 (fr) * 2013-12-20 2017-08-02 DH Technologies Development PTE. Ltd. Source ionique pour spectrométrie de masse
CN107703204B (zh) * 2017-09-26 2021-09-14 中国检验检疫科学研究院 一种杀虫剂产品中禁用农药的快速检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4008388A (en) * 1974-05-16 1977-02-15 Universal Monitor Corporation Mass spectrometric system for rapid, automatic and specific identification and quantitation of compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2457562A1 (fr) * 1979-05-25 1980-12-19 Hewlett Packard Co Appareil permettant d'analyser des echantillons de liquide au moyen d'un spectrometre de masse
WO1993017320A1 (fr) * 1992-02-19 1993-09-02 Fisons Plc Chambre d'evaporation et nebulisateur d'echantillon pour spectrometre a emission de plasma a couplage inductif (icp) et de plasma a induction micro-onde (mip) ou de masse et spectrometres les contenant
US5534998A (en) * 1992-02-19 1996-07-09 Fisons Plc Sample nebulizer and evaporation chamber for ICP and MIP emission or mass spectrometry and spectrometers comprising the same
ES2109159A1 (es) * 1995-04-26 1998-01-01 Univ Alicante Sistema de desolvatacion por microondas para uso en espectrometria atomica.

Also Published As

Publication number Publication date
DE2728944B2 (de) 1980-06-04
DE2728944A1 (de) 1978-01-12
DE2728944C3 (de) 1981-06-04
GB1524759A (en) 1978-09-13
JPS5843692B2 (ja) 1983-09-28
FR2356927B1 (fr) 1979-03-09
JPS533290A (en) 1978-01-12
US4112297A (en) 1978-09-05

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