FR2354092A1 - TRETINOINE IN A GEL EXCIPIENT FOR THE TREATMENT OF ACNE - Google Patents

TRETINOINE IN A GEL EXCIPIENT FOR THE TREATMENT OF ACNE

Info

Publication number
FR2354092A1
FR2354092A1 FR7600725A FR7600725A FR2354092A1 FR 2354092 A1 FR2354092 A1 FR 2354092A1 FR 7600725 A FR7600725 A FR 7600725A FR 7600725 A FR7600725 A FR 7600725A FR 2354092 A1 FR2354092 A1 FR 2354092A1
Authority
FR
France
Prior art keywords
acne
treatment
gel
tretinoine
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7600725A
Other languages
French (fr)
Other versions
FR2354092B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson
Original Assignee
Johnson and Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson filed Critical Johnson and Johnson
Publication of FR2354092A1 publication Critical patent/FR2354092A1/en
Application granted granted Critical
Publication of FR2354092B1 publication Critical patent/FR2354092B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Abstract

La présente invention concerne une composition de gel pour le traitement de l'acné. Selon l'invention, cette composition de gel pour traitement de l'acné est efficace à de faibles concentrations de trétinoine, pour l'application topique. La composition est hautement efficace dans le traitement des conditions de l'acné et est capable d'être stockée sans réfrigération pendant de longues durées sans perte de l'efficacité thérapeutique et tout en maintenant l'uniformité et la stabilité du gel. La présente invention s'applique notamment au traitement des desordres dermatologiques tels que l'acné qui se présente sous la forme de comédons ou de points noirs, de follicules, de pustules, de papules, de kystes et de nodules.The present invention relates to a gel composition for the treatment of acne. According to the invention, this gel composition for the treatment of acne is effective at low concentrations of tretinoin, for topical application. The composition is highly effective in treating acne conditions and is able to be stored without refrigeration for long periods of time without loss of therapeutic efficacy and while maintaining gel uniformity and stability. The present invention applies in particular to the treatment of dermatological disorders such as acne which is in the form of comedones or blackheads, follicles, pustules, papules, cysts and nodules.

FR7600725A 1975-01-17 1976-01-13 TRETINOINE IN A GEL EXCIPIENT FOR THE TREATMENT OF ACNE Granted FR2354092A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54190675A 1975-01-17 1975-01-17

Publications (2)

Publication Number Publication Date
FR2354092A1 true FR2354092A1 (en) 1978-01-06
FR2354092B1 FR2354092B1 (en) 1981-09-18

Family

ID=24161582

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7600725A Granted FR2354092A1 (en) 1975-01-17 1976-01-13 TRETINOINE IN A GEL EXCIPIENT FOR THE TREATMENT OF ACNE

Country Status (18)

Country Link
AT (1) AT363191B (en)
AU (1) AU499339B2 (en)
BE (1) BE837662A (en)
CA (1) CA1063515A (en)
DE (1) DE2601489A1 (en)
DK (1) DK157781C (en)
FI (1) FI56931B (en)
FR (1) FR2354092A1 (en)
GB (1) GB1476717A (en)
IN (1) IN142640B (en)
LU (1) LU74195A1 (en)
NL (1) NL7600388A (en)
NO (1) NO760149L (en)
NZ (1) NZ179755A (en)
PH (1) PH18090A (en)
PT (1) PT64709B (en)
SE (1) SE429924B (en)
ZA (1) ZA76251B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004052353A2 (en) * 2002-12-12 2004-06-24 Galderma Research & Development, Snc Aqueous-alcoholic depigmenting gel containing a phenolic derivative and a retinoid

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4214000A (en) 1978-10-30 1980-07-22 Johnson & Johnson Zinc salt of all-trans-retinoic acid for the treatment of acne
JPS58164508A (en) * 1982-03-26 1983-09-29 Eisai Co Ltd Composition for external use containing isoprenyl-carboxylic acid
CH655656B (en) * 1982-10-07 1986-05-15
US4889847A (en) * 1986-11-03 1989-12-26 Ortho Pharmaceutical Corporation Prevention of glucocorticoid-induced skin atrophy
MY105521A (en) * 1989-04-17 1994-10-31 Healthpoint Ltd Moisturizing vehicle for topical application of vitamin a acid.
NZ244862A (en) * 1991-10-23 1995-07-26 Block Drug Co Use of vitamin e in topical pharmaceuticals to enhance penetration of the active agent
GB9125712D0 (en) * 1991-12-03 1992-01-29 Smithkline Beecham Plc Skin care composition
AU670777B2 (en) * 1992-04-16 1996-08-01 Ortho Pharmaceutical Corporation Aqueous gel vehicles for retinoids
GB2268402A (en) * 1992-06-19 1994-01-12 Ian Donald Morrison Compositions for treating skin disorders
FR2761600B1 (en) 1998-06-19 2000-03-31 Oreal FOAMING COMPOSITION FOR THE WASHING AND TREATMENT OF HAIR AND / OR SCALP BASED ON AN ACTIVE INGREDIENT, AN ANIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT AND A PROPENETANT
CN100464741C (en) * 2002-12-12 2009-03-04 盖尔德马研究及发展公司 Aqueous-alcoholic depigmenting gel containing a phenolic derivative and a retinoid
FR2857266B1 (en) * 2003-07-07 2007-09-21 Jean Noel Thorel COMPOSITION FOR DERMATOLOGICAL AND / OR COSMETIC USE, COMPRISING AS ACTIVE INGREDIENT AT LEAST ONE LIPOPHILIC ANTIOXIDANT
CN101522200A (en) * 2005-03-24 2009-09-02 安纳考尔医药公司 Topical formulations of borinic acid antibodies and their methods of use
US20100215700A1 (en) 2009-02-25 2010-08-26 Conopco, Inc., D/B/A Unilever Shear Gels and Compositions Comprising Shear Gels

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL257621A (en) * 1959-11-23
US3729568A (en) * 1969-09-23 1973-04-24 Johnson & Johnson Acne treatment

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004052353A2 (en) * 2002-12-12 2004-06-24 Galderma Research & Development, Snc Aqueous-alcoholic depigmenting gel containing a phenolic derivative and a retinoid
WO2004052353A3 (en) * 2002-12-12 2004-07-15 Galderma Res & Dev Aqueous-alcoholic depigmenting gel containing a phenolic derivative and a retinoid
JP2006510652A (en) * 2002-12-12 2006-03-30 ガルデルマ・リサーチ・アンド・デヴェロップメント・エス・エヌ・セ Water-alcohol decolorization gel containing phenol derivatives and retinoids
JP2010095534A (en) * 2002-12-12 2010-04-30 Galderma Research & Development Aqueous-alcoholic depigmenting gel containing phenolic derivative and retinoid

Also Published As

Publication number Publication date
DE2601489A1 (en) 1976-07-22
AU499339B2 (en) 1979-04-12
ATA27276A (en) 1980-12-15
AU1035176A (en) 1977-07-21
SE7600436L (en) 1976-07-18
DK157781C (en) 1990-08-13
NZ179755A (en) 1978-06-20
FR2354092B1 (en) 1981-09-18
DK18276A (en) 1976-07-18
GB1476717A (en) 1977-06-16
SE429924B (en) 1983-10-10
ZA76251B (en) 1977-08-31
BE837662A (en) 1976-07-16
CA1063515A (en) 1979-10-02
AT363191B (en) 1981-07-10
PT64709A (en) 1976-02-01
PT64709B (en) 1978-01-04
DK157781B (en) 1990-02-19
FI760089A (en) 1976-07-18
NL7600388A (en) 1976-07-20
DE2601489C2 (en) 1990-02-01
NO760149L (en) 1976-07-20
PH18090A (en) 1985-03-20
IN142640B (en) 1977-08-06
FI56931B (en) 1980-01-31
LU74195A1 (en) 1976-05-18

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