FR2343752A1 - Complexes alcooliques du phosphate d'estramustine, leur preparation et leur application a titre d'intermediaires dans la purification de ce compose et de ses sels - Google Patents
Complexes alcooliques du phosphate d'estramustine, leur preparation et leur application a titre d'intermediaires dans la purification de ce compose et de ses selsInfo
- Publication number
- FR2343752A1 FR2343752A1 FR7707129A FR7707129A FR2343752A1 FR 2343752 A1 FR2343752 A1 FR 2343752A1 FR 7707129 A FR7707129 A FR 7707129A FR 7707129 A FR7707129 A FR 7707129A FR 2343752 A1 FR2343752 A1 FR 2343752A1
- Authority
- FR
- France
- Prior art keywords
- intermediaries
- purification
- salts
- compound
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910019142 PO4 Inorganic materials 0.000 title 1
- 230000001476 alcoholic effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- FRPJXPJMRWBBIH-RBRWEJTLSA-N estramustine Chemical compound ClCCN(CCCl)C(=O)OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 FRPJXPJMRWBBIH-RBRWEJTLSA-N 0.000 title 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title 1
- 239000010452 phosphate Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9451/76A GB1523035A (en) | 1976-03-10 | 1976-03-10 | Derivatives of estradiol - 17 - dihydrogen phosphates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2343752A1 true FR2343752A1 (fr) | 1977-10-07 |
| FR2343752B1 FR2343752B1 (en:Method) | 1978-10-20 |
Family
ID=9872205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7707129A Granted FR2343752A1 (fr) | 1976-03-10 | 1977-03-10 | Complexes alcooliques du phosphate d'estramustine, leur preparation et leur application a titre d'intermediaires dans la purification de ce compose et de ses sels |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4115414A (en:Method) |
| JP (2) | JPS52108963A (en:Method) |
| AT (1) | AT355737B (en:Method) |
| BE (1) | BE852271A (en:Method) |
| CA (1) | CA1083140A (en:Method) |
| CH (1) | CH633813A5 (en:Method) |
| DE (1) | DE2710293C2 (en:Method) |
| DK (1) | DK156007C (en:Method) |
| FR (1) | FR2343752A1 (en:Method) |
| GB (1) | GB1523035A (en:Method) |
| IE (1) | IE45024B1 (en:Method) |
| IL (1) | IL51592A (en:Method) |
| IT (1) | IT1075668B (en:Method) |
| LU (1) | LU76927A1 (en:Method) |
| MX (1) | MX5242E (en:Method) |
| NL (1) | NL7702608A (en:Method) |
| SE (1) | SE428928B (en:Method) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0612760A3 (en) * | 1993-02-18 | 1995-08-30 | Permachem Asia Ltd | Process for the purification of estramustin phosphate or its salts. |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6040255A (en) * | 1996-06-25 | 2000-03-21 | Kimberly-Clark Worldwide, Inc. | Photostabilization package usable in nonwoven fabrics and nonwoven fabrics containing same |
| US20040072889A1 (en) * | 1997-04-21 | 2004-04-15 | Pharmacia Corporation | Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia |
| GB9921958D0 (en) * | 1999-09-16 | 1999-11-17 | Pharmacia & Upjohn Spa | Formulations for parenteral use of estramustine phosphate and sulfoalkylether-cyclodextrins |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3299104A (en) | 1963-04-09 | 1967-01-17 | Leo Ab | Certain steroid nu-bis-(haloethyl)-carbamates |
| GB1458372A (en) * | 1973-03-05 | 1976-12-15 | Leo Ab | Steroid carbamates and allophanates |
-
1976
- 1976-03-10 GB GB9451/76A patent/GB1523035A/en not_active Expired
-
1977
- 1977-03-03 IL IL51592A patent/IL51592A/xx unknown
- 1977-03-03 US US05/773,911 patent/US4115414A/en not_active Expired - Lifetime
- 1977-03-08 SE SE7702613A patent/SE428928B/xx not_active IP Right Cessation
- 1977-03-09 MX MX775524U patent/MX5242E/es unknown
- 1977-03-09 IE IE523/77A patent/IE45024B1/en unknown
- 1977-03-09 DE DE2710293A patent/DE2710293C2/de not_active Expired
- 1977-03-09 BE BE175633A patent/BE852271A/xx not_active IP Right Cessation
- 1977-03-09 AT AT157777A patent/AT355737B/de not_active IP Right Cessation
- 1977-03-09 DK DK103577A patent/DK156007C/da not_active IP Right Cessation
- 1977-03-09 CA CA273,564A patent/CA1083140A/en not_active Expired
- 1977-03-10 JP JP2550877A patent/JPS52108963A/ja active Granted
- 1977-03-10 NL NL7702608A patent/NL7702608A/xx not_active Application Discontinuation
- 1977-03-10 IT IT21129/77A patent/IT1075668B/it active
- 1977-03-10 LU LU76927A patent/LU76927A1/xx unknown
- 1977-03-10 FR FR7707129A patent/FR2343752A1/fr active Granted
- 1977-03-10 CH CH304777A patent/CH633813A5/de not_active IP Right Cessation
-
1979
- 1979-12-25 JP JP16774779A patent/JPS5589300A/ja active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0612760A3 (en) * | 1993-02-18 | 1995-08-30 | Permachem Asia Ltd | Process for the purification of estramustin phosphate or its salts. |
Also Published As
| Publication number | Publication date |
|---|---|
| ATA157777A (de) | 1979-08-15 |
| LU76927A1 (en:Method) | 1978-10-18 |
| BE852271A (fr) | 1977-09-09 |
| DK103577A (da) | 1977-09-11 |
| IE45024B1 (en) | 1982-06-02 |
| IL51592A0 (en) | 1977-05-31 |
| IE45024L (en) | 1977-09-10 |
| DK156007B (da) | 1989-06-12 |
| SE7702613L (sv) | 1977-09-11 |
| AT355737B (de) | 1980-03-25 |
| IT1075668B (it) | 1985-04-22 |
| GB1523035A (en) | 1978-08-31 |
| DE2710293A1 (de) | 1977-09-15 |
| FR2343752B1 (en:Method) | 1978-10-20 |
| CA1083140A (en) | 1980-08-05 |
| NL7702608A (nl) | 1977-09-13 |
| DK156007C (da) | 1989-11-06 |
| JPS52108963A (en) | 1977-09-12 |
| JPS5589300A (en) | 1980-07-05 |
| JPS5526160B2 (en:Method) | 1980-07-11 |
| MX5242E (es) | 1983-05-16 |
| SE428928B (sv) | 1983-08-01 |
| CH633813A5 (de) | 1982-12-31 |
| DE2710293C2 (de) | 1986-06-12 |
| US4115414A (en) | 1978-09-19 |
| JPS5755720B2 (en:Method) | 1982-11-25 |
| IL51592A (en) | 1980-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |