FR2342288A1 - Procede pour la preparation de codeinone a partir de thebaine - Google Patents
Procede pour la preparation de codeinone a partir de thebaineInfo
- Publication number
- FR2342288A1 FR2342288A1 FR7605406A FR7605406A FR2342288A1 FR 2342288 A1 FR2342288 A1 FR 2342288A1 FR 7605406 A FR7605406 A FR 7605406A FR 7605406 A FR7605406 A FR 7605406A FR 2342288 A1 FR2342288 A1 FR 2342288A1
- Authority
- FR
- France
- Prior art keywords
- codeinone
- thebaine
- reacting
- catalyst
- prepn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 239000003054 catalyst Substances 0.000 title abstract 2
- XYYVYLMBEZUESM-CMKMFDCUSA-N codeinone Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=CC(=O)[C@@H]1OC1=C2C3=CC=C1OC XYYVYLMBEZUESM-CMKMFDCUSA-N 0.000 title abstract 2
- XYYVYLMBEZUESM-UHFFFAOYSA-N dihydrocodeine Natural products C1C(N(CCC234)C)C2C=CC(=O)C3OC2=C4C1=CC=C2OC XYYVYLMBEZUESM-UHFFFAOYSA-N 0.000 title abstract 2
- FQXXSQDCDRQNQE-UHFFFAOYSA-N markiertes Thebain Natural products COC1=CC=C2C(N(CC3)C)CC4=CC=C(OC)C5=C4C23C1O5 FQXXSQDCDRQNQE-UHFFFAOYSA-N 0.000 title abstract 2
- FQXXSQDCDRQNQE-VMDGZTHMSA-N thebaine Chemical compound C([C@@H](N(CC1)C)C2=CC=C3OC)C4=CC=C(OC)C5=C4[C@@]21[C@H]3O5 FQXXSQDCDRQNQE-VMDGZTHMSA-N 0.000 title abstract 2
- 229930003945 thebaine Natural products 0.000 title abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 title 1
- 229910052740 iodine Inorganic materials 0.000 title 1
- 239000011630 iodine Substances 0.000 title 1
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7605406A FR2342288A1 (fr) | 1976-02-26 | 1976-02-26 | Procede pour la preparation de codeinone a partir de thebaine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7605406A FR2342288A1 (fr) | 1976-02-26 | 1976-02-26 | Procede pour la preparation de codeinone a partir de thebaine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2342288A1 true FR2342288A1 (fr) | 1977-09-23 |
| FR2342288B1 FR2342288B1 (enrdf_load_stackoverflow) | 1979-07-20 |
Family
ID=9169647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7605406A Granted FR2342288A1 (fr) | 1976-02-26 | 1976-02-26 | Procede pour la preparation de codeinone a partir de thebaine |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2342288A1 (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2362144A1 (fr) * | 1976-08-17 | 1978-03-17 | Macfarlan Smith Ltd | Derives de la dihydrocodeinone, leur preparation et leur emploi dans la synthese de la codeine |
-
1976
- 1976-02-26 FR FR7605406A patent/FR2342288A1/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2362144A1 (fr) * | 1976-08-17 | 1978-03-17 | Macfarlan Smith Ltd | Derives de la dihydrocodeinone, leur preparation et leur emploi dans la synthese de la codeine |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2342288B1 (enrdf_load_stackoverflow) | 1979-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |