FR2340924A1 - 2'-(carboxymethoxy)-chalcones et leur utilisation contre les ulceres d'estomac et du duodenum - Google Patents

2'-(carboxymethoxy)-chalcones et leur utilisation contre les ulceres d'estomac et du duodenum

Info

Publication number
FR2340924A1
FR2340924A1 FR7702191A FR7702191A FR2340924A1 FR 2340924 A1 FR2340924 A1 FR 2340924A1 FR 7702191 A FR7702191 A FR 7702191A FR 7702191 A FR7702191 A FR 7702191A FR 2340924 A1 FR2340924 A1 FR 2340924A1
Authority
FR
France
Prior art keywords
chalcones
carboxymethoxy
use against
against stomach
duodenum ulcers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7702191A
Other languages
English (en)
French (fr)
Other versions
FR2340924B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Kazuaki Kyogoku
Katsuo Hatayama
Sadakazu Yokomori
Jiro Sawada
Ichiro Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taisho Pharmaceutical Co Ltd
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of FR2340924A1 publication Critical patent/FR2340924A1/fr
Application granted granted Critical
Publication of FR2340924B1 publication Critical patent/FR2340924B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/90Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7702191A 1976-02-13 1977-01-26 2'-(carboxymethoxy)-chalcones et leur utilisation contre les ulceres d'estomac et du duodenum Granted FR2340924A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1457876A JPS5297950A (en) 1976-02-13 1976-02-13 Chalconeether derivatives

Publications (2)

Publication Number Publication Date
FR2340924A1 true FR2340924A1 (fr) 1977-09-09
FR2340924B1 FR2340924B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-03-23

Family

ID=11865033

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7702191A Granted FR2340924A1 (fr) 1976-02-13 1977-01-26 2'-(carboxymethoxy)-chalcones et leur utilisation contre les ulceres d'estomac et du duodenum

Country Status (12)

Country Link
US (1) US4085135A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5297950A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR209544A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1084064A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH605537A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2705603C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES455620A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2340924A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1523241A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU173019B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT66118B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU39378B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190671A (en) * 1977-03-17 1980-02-26 Biorex Laboratories Limited Chalcone derivatives
JPS5552597U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1978-09-30 1980-04-08
JPS62207212A (ja) * 1986-03-08 1987-09-11 Nippon Haipotsukusu:Kk 抗アレルギ−剤
US5089654A (en) * 1989-08-08 1992-02-18 Taisho Pharmaceutical Co., Ltd. Chalcone derivatives
AU742787B2 (en) 1997-07-09 2002-01-10 Androsolutions, Inc. Improved methods and compositions for treating male erectile dysfunction
US6103765A (en) * 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
KR20030031500A (ko) * 2000-06-20 2003-04-21 아테로제닉스, 인코포레이티드 1,3-비스-(치환된-페닐)-2-프로펜-1-온 및 vcam-1매개된 질환을 치료하기 위한 그의 용도
AU2002248910A1 (en) 2000-11-17 2002-05-27 Idenix (Cayman) Limited Methods for inhibiting the transmission of HIV using topically applied substituted 6-benzyl-4-oxopyrmidines
HUP0500165A2 (en) * 2001-12-19 2006-09-28 Atherogenics Inc Chalcone derivatives and their use to treat diseases
WO2004056727A2 (en) * 2002-12-19 2004-07-08 Atherogenics, Inc. Process of making chalcone derivatives
US7173129B2 (en) * 2003-06-06 2007-02-06 Athero Genics, Inc. Sulfonamide-substituted chalcone derivatives and their use to treat diseases
WO2006004903A2 (en) * 2004-06-28 2006-01-12 Atherogenics, Inc. 1,2-bis-(substituted-phenyl)-2-propen-1-ones and pharmaceutical compositions thereof
WO2009122435A2 (en) * 2008-03-31 2009-10-08 Council Of Scientific & Industrial Research A simultaneous method for the preparation of a mixture of 3- acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3- acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
CN101817741B (zh) * 2009-12-10 2013-10-16 天津药物研究院 索法酮的晶型ⅸ及其制备方法和用途
CN101781194B (zh) * 2009-12-10 2013-05-15 天津药物研究院 索法酮的晶型ⅴ及其制备方法和用途
CN101792385B (zh) * 2009-12-10 2013-05-15 天津药物研究院 索法酮的晶型ⅷ及其制备方法和用途
CN101735038B (zh) * 2009-12-10 2013-06-26 天津药物研究院 索法酮的晶型ⅰ及其制备方法和用途
CN101735040B (zh) * 2009-12-10 2013-05-15 天津药物研究院 索法酮的晶型ⅲ及其制备方法和用途
CN101817742B (zh) * 2009-12-10 2013-10-16 天津药物研究院 索法酮的晶型ⅹ及其制备方法和用途
CN101735039B (zh) * 2009-12-10 2013-06-26 天津药物研究院 索法酮的晶型ⅱ及其制备方法和用途
CN101781195B (zh) * 2009-12-10 2013-03-13 天津药物研究院 索法酮的晶型ⅶ及其制备方法和用途
CN101781193B (zh) * 2009-12-10 2013-05-15 天津药物研究院 索法酮的晶型ⅳ及其制备方法和用途
CN101781192B (zh) * 2009-12-10 2013-05-15 天津药物研究院 索法酮的晶型ⅵ及其制备方法和用途
CN115368265B (zh) * 2022-10-24 2023-03-28 中国中医科学院中药研究所 一种索法酮小分子活性探针及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3255241A (en) * 1961-01-19 1966-06-07 Merck & Co Inc (2-alkylidene acyl)phenoxy-and (2-alkylidene acyl)phenylmercaptocarboxylic acids
CH593224A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1973-10-30 1977-11-30 Taisho Pharmaceutical Co Ltd

Also Published As

Publication number Publication date
YU39378B (en) 1984-12-31
AU2131077A (en) 1978-01-26
HU173019B (hu) 1979-01-28
CH605537A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1978-09-29
AR209544A1 (es) 1977-04-29
ES455620A1 (es) 1978-01-01
JPS5645896B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-10-29
US4085135A (en) 1978-04-18
DE2705603C2 (de) 1986-07-24
YU8977A (en) 1982-06-30
GB1523241A (en) 1978-08-31
JPS5297950A (en) 1977-08-17
CA1084064A (en) 1980-08-19
PT66118A (en) 1977-02-01
PT66118B (en) 1978-06-28
DE2705603A1 (de) 1977-08-18
FR2340924B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-03-23

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