FR2340730B1 - - Google Patents

Info

Publication number
FR2340730B1
FR2340730B1 FR7603604A FR7603604A FR2340730B1 FR 2340730 B1 FR2340730 B1 FR 2340730B1 FR 7603604 A FR7603604 A FR 7603604A FR 7603604 A FR7603604 A FR 7603604A FR 2340730 B1 FR2340730 B1 FR 2340730B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7603604A
Other languages
French (fr)
Other versions
FR2340730A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7603604A priority Critical patent/FR2340730A1/fr
Priority to NLAANVRAGE7701107,A priority patent/NL171985C/xx
Priority to IL7751403A priority patent/IL51403A/xx
Priority to HU77RO00000914A priority patent/HU172528B/hu
Priority to PH7719438A priority patent/PH12367A/en
Priority to ZA770743A priority patent/ZA77743B/xx
Priority to CH158277A priority patent/CH618699A5/fr
Priority to CA271,425A priority patent/CA1073906A/fr
Priority to IE270/77A priority patent/IE44561B1/en
Priority to SU772449656A priority patent/SU683622A3/ru
Priority to GB5365/77A priority patent/GB1518071A/en
Priority to LU76728A priority patent/LU76728A1/xx
Priority to SE7701460A priority patent/SE427274B/xx
Priority to AU22138/77A priority patent/AU509092B2/en
Priority to US05/766,966 priority patent/US4110450A/en
Priority to ZM14/77A priority patent/ZM1477A1/xx
Priority to DK55477A priority patent/DK55477A/da
Priority to BE174799A priority patent/BE851262A/xx
Priority to AR266495A priority patent/AR224095A1/es
Priority to EG78/77A priority patent/EG13739A/xx
Priority to MW4/77A priority patent/MW477A1/xx
Priority to JP52013472A priority patent/JPS5822119B2/ja
Priority to PT66175A priority patent/PT66175B/pt
Priority to AT90277A priority patent/AT348535B/de
Priority to DE2705641A priority patent/DE2705641C3/de
Priority to OA56067A priority patent/OA05565A/xx
Priority to ES455790A priority patent/ES455790A1/es
Priority to ES458689A priority patent/ES458689A1/es
Priority to ES458687A priority patent/ES458687A1/es
Priority to ES458688A priority patent/ES458688A1/es
Publication of FR2340730A1 publication Critical patent/FR2340730A1/fr
Priority to US05/855,196 priority patent/US4144339A/en
Priority to US05/855,385 priority patent/US4138487A/en
Priority to CH1030879A priority patent/CH619463A5/fr
Application granted granted Critical
Publication of FR2340730B1 publication Critical patent/FR2340730B1/fr
Priority to HK174/81A priority patent/HK17481A/xx
Priority to KE3126A priority patent/KE3126A/xx
Priority to JP56146022A priority patent/JPS591709B2/ja
Priority to JP56146023A priority patent/JPS591710B2/ja
Priority to MY1/82A priority patent/MY8200001A/xx
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/08Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/38One sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/16Halogen atoms; Nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7603604A 1976-02-10 1976-02-10 Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent Granted FR2340730A1 (fr)

Priority Applications (38)

Application Number Priority Date Filing Date Title
FR7603604A FR2340730A1 (fr) 1976-02-10 1976-02-10 Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent
NLAANVRAGE7701107,A NL171985C (nl) 1976-02-10 1977-02-02 Werkwijze voor het bereiden van preparaten met werking tegen schistosomiasis, de aldus verkregen gevormde preparaten en werkwijze voor het bereiden van 1,2-dithioolverbindingen.
HU77RO00000914A HU172528B (hu) 1976-02-10 1977-02-08 Sposob poluchenija novykh proizvodnykh s 1,2-ditiol-3-tion gruppoj
IL7751403A IL51403A (en) 1976-02-10 1977-02-08 5-diazinyl-1,2-dithiole-3-thione derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
EG78/77A EG13739A (en) 1976-02-10 1977-02-09 Nouveaux derives du dithiole 1,2 leur preparation et les compositions qui les contiennent
CH158277A CH618699A5 (de) 1976-02-10 1977-02-09
CA271,425A CA1073906A (fr) 1976-02-10 1977-02-09 Derives du dithiole-1,2, leur preparation et les compositions qui les contiennent
IE270/77A IE44561B1 (en) 1976-02-10 1977-02-09 1,2-dithiole derivatives
SU772449656A SU683622A3 (ru) 1976-02-10 1977-02-09 Способ получени производных 1,2-дитиоланов
GB5365/77A GB1518071A (en) 1976-02-10 1977-02-09 1,2-dithiole derivatives
LU76728A LU76728A1 (de) 1976-02-10 1977-02-09
SE7701460A SE427274B (sv) 1976-02-10 1977-02-09 Forfarande for framstellning av derivat av 1,2-ditiol-3-tion med verkan mot blodparasiter
AU22138/77A AU509092B2 (en) 1976-02-10 1977-02-09 1, 2-dithiole derivatives
US05/766,966 US4110450A (en) 1976-02-10 1977-02-09 1,2-dithiole derivatives
ZM14/77A ZM1477A1 (en) 1976-02-10 1977-02-09 1,2-dithiole derivatives
DK55477A DK55477A (da) 1976-02-10 1977-02-09 Fremgangsmade til fremstilling af derivater af 1,2-dithiol
BE174799A BE851262A (de) 1976-02-10 1977-02-09
AR266495A AR224095A1 (es) 1976-02-10 1977-02-09 Procedimiento de preparacion de nuevos derivados de ditiol-1,2 tiona-3
PH7719438A PH12367A (en) 1976-02-10 1977-02-09 1,2-dithiole derivatives
MW4/77A MW477A1 (en) 1976-02-10 1977-02-09 1,2-dithiole derivatives
JP52013472A JPS5822119B2 (ja) 1976-02-10 1977-02-09 ジチオ−ル誘導体
PT66175A PT66175B (fr) 1976-02-10 1977-02-09 Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent
ZA770743A ZA77743B (en) 1976-02-10 1977-02-09 1,2-dithiole derivatives
AT90277A AT348535B (de) 1976-02-10 1977-02-10 Verfahren zur herstellung von neuen 1,2- dithiolderivaten
DE2705641A DE2705641C3 (de) 1976-02-10 1977-02-10 U-Dithiol-3-thione, Verfahren zu deren Herstellung und diese enthaltende Zusammensetzungen
OA56067A OA05565A (fr) 1976-02-10 1977-02-10 Nouveaux dérivés du dithiole-1,2 et leur procédé de préparation.
ES455790A ES455790A1 (es) 1976-02-10 1977-02-10 Procedimiento de preparacion de nuevos derivados del di- tiol-1,2.
ES458689A ES458689A1 (es) 1976-02-10 1977-05-11 Procedimiento de preparacion de nuevos derivados del ditiol-1,2.
ES458687A ES458687A1 (es) 1976-02-10 1977-05-11 Procedimiento de preparacion de nuevos derivado del ditiol -1,2.
ES458688A ES458688A1 (es) 1976-02-10 1977-05-11 Procedimiento de preparacion de nuevos derivados del ditiol-1,2.
US05/855,196 US4144339A (en) 1976-02-10 1977-11-28 1,2-Dithiole pyrimidines
US05/855,385 US4138487A (en) 1976-02-10 1977-11-28 1,2-Dithiole derivatives
CH1030879A CH619463A5 (de) 1976-02-10 1979-11-19
HK174/81A HK17481A (en) 1976-02-10 1981-04-30 1,2-dithiole derivatives
KE3126A KE3126A (en) 1976-02-10 1981-05-06 1,2-dithiole derivatives
JP56146022A JPS591709B2 (ja) 1976-02-10 1981-09-16 1,2−ジチオ−ル
JP56146023A JPS591710B2 (ja) 1976-02-10 1981-09-16 1,2−ジチオ−ル化合物
MY1/82A MY8200001A (en) 1976-02-10 1982-12-30 1,2 - dithiole derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7603604A FR2340730A1 (fr) 1976-02-10 1976-02-10 Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
FR2340730A1 FR2340730A1 (fr) 1977-09-09
FR2340730B1 true FR2340730B1 (de) 1980-05-09

Family

ID=9168948

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7603604A Granted FR2340730A1 (fr) 1976-02-10 1976-02-10 Nouveaux derives du dithiole-1,2, leur preparation et les compositions qui les contiennent

Country Status (5)

Country Link
JP (2) JPS591709B2 (de)
BE (1) BE851262A (de)
FR (1) FR2340730A1 (de)
MW (1) MW477A1 (de)
ZA (1) ZA77743B (de)

Also Published As

Publication number Publication date
JPS591709B2 (ja) 1984-01-13
FR2340730A1 (fr) 1977-09-09
JPS591710B2 (ja) 1984-01-13
JPS57112391A (en) 1982-07-13
JPS5781484A (en) 1982-05-21
BE851262A (de) 1977-08-09
ZA77743B (en) 1977-12-28
MW477A1 (en) 1978-05-10

Similar Documents

Publication Publication Date Title
DK142252C (de)
DK141392C (de)
JPS5730248B2 (de)
JPS5719867Y2 (de)
DE2715512C3 (de)
JPS5747505Y2 (de)
FR2340730B1 (de)
JPS5724005Y2 (de)
JPS5318364U (de)
CS186526B1 (de)
JPS5323203U (de)
CH600574A5 (de)
CH606592A5 (de)
BG23287A1 (de)
BG23436A1 (de)
CH590689A5 (de)
CH594478A5 (de)
CH594511A5 (de)
CH598074A5 (de)
CH598142A5 (de)
CH598256A5 (de)
CH600135A5 (de)
CH600257A5 (de)
BG23014A1 (de)
CH600865A5 (de)

Legal Events

Date Code Title Description
ST Notification of lapse