FR2338039B1 - - Google Patents
Info
- Publication number
- FR2338039B1 FR2338039B1 FR7628826A FR7628826A FR2338039B1 FR 2338039 B1 FR2338039 B1 FR 2338039B1 FR 7628826 A FR7628826 A FR 7628826A FR 7628826 A FR7628826 A FR 7628826A FR 2338039 B1 FR2338039 B1 FR 2338039B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP51002458A JPS5922697B2 (ja) | 1976-01-13 | 1976-01-13 | ビス−（メタ−アミジノフエノキシ）−化合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2338039A1 FR2338039A1 (fr) | 1977-08-12 |
| FR2338039B1 true FR2338039B1 (US20100223739A1-20100909-C00005.png) | 1980-03-07 |
Family
ID=11529845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7628826A Granted FR2338039A1 (fr) | 1976-01-13 | 1976-09-24 | Composes bis-(meta-amidinophenoxy) et leurs sels d'addition avec des acides pharmacologiquement acceptables |
Country Status (5)
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2397387A1 (fr) * | 1976-04-27 | 1979-02-09 | Serobiologiques Lab Sa | 4,4'-bis-formyl-polyhalo-diphenoxyalcanes, procede de preparation et application a la synthese de 4,4'-dicyano-polyhalo-diphenoxyalcanes |
| US4262021A (en) * | 1977-08-18 | 1981-04-14 | Pfizer Inc. | Antiviral amine and amidine derivatives of glycerol and propanediols |
| US5084480A (en) * | 1987-11-06 | 1992-01-28 | Fujisawa Usa, Inc. | Pentamidine salts useful in the treatment of pneumocystis carinii pneumonia |
| AU6643790A (en) * | 1989-11-09 | 1991-06-13 | Roger Reed | Digital circuit for a frequency modulation and carrier synthesis in a digital radio system |
| US5451700A (en) * | 1991-06-11 | 1995-09-19 | Ciba-Geigy Corporation | Amidino compounds, their manufacture and methods of treatment |
| US5488160A (en) * | 1991-06-11 | 1996-01-30 | Ciba-Geigy Corporation | Amidino compounds, their manufacture and method of treatment |
| MY107993A (en) * | 1991-06-19 | 1996-07-15 | Schering Corp | Orally active antiviral compounds. |
| US5455274A (en) * | 1992-12-09 | 1995-10-03 | Ciba-Geigy Corporation | Hydroxyamidine derivatives |
| US5691364A (en) * | 1995-03-10 | 1997-11-25 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| AU707323B2 (en) * | 1995-03-10 | 1999-07-08 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| US5723495A (en) * | 1995-11-16 | 1998-03-03 | The University Of North Carolina At Chapel Hill | Benzamidoxime prodrugs as antipneumocystic agents |
| US5994375A (en) * | 1996-02-12 | 1999-11-30 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants |
| US5753635A (en) * | 1996-08-16 | 1998-05-19 | Berlex Laboratories, Inc. | Purine derivatives and their use as anti-coagulants |
| DE69717474T2 (de) | 1996-09-12 | 2003-06-26 | Schering Ag | Durch cyclische aminosäuren oder cyclische hydroxysäuren substituierte benzamidinderivate und deren verwendung als antikoagulantien |
| US6008234A (en) * | 1996-09-12 | 1999-12-28 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants |
| US6004985A (en) * | 1996-10-09 | 1999-12-21 | Berlex Laboratories, Inc. | Thio acid derived monocylic N-heterocyclics as anticoagulants |
| US6686364B2 (en) | 1997-12-08 | 2004-02-03 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| CA2315070A1 (en) | 1997-12-17 | 1999-07-01 | Schering Aktiengesellschaft | Ortho-anthranilamide derivatives as anti-coagulants |
| US6140351A (en) * | 1997-12-19 | 2000-10-31 | Berlex Laboratories, Inc. | Ortho-anthranilamide derivatives as anti-coagulants |
| DE19819548A1 (de) | 1998-04-30 | 1999-11-04 | Merck Patent Gmbh | Biphenylderivate |
| CA2344445A1 (en) * | 1998-09-17 | 2000-03-23 | The University Of North Carolina At Chapel Hill | Antifungal activity of dicationic molecules |
| EP1685836A3 (en) * | 1998-09-17 | 2007-05-09 | University Of North Carolina At Chapel Hill | Antifungal activity of dicationic molecules |
| US6262088B1 (en) | 1998-11-19 | 2001-07-17 | Berlex Laboratories, Inc. | Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants |
| US6127376A (en) * | 1998-12-04 | 2000-10-03 | Berlex Laboratories, Inc. | Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants |
| US6350761B1 (en) | 1999-07-30 | 2002-02-26 | Berlex Laboratories, Inc. | Benzenamine derivatives as anti-coagulants |
| JP4664634B2 (ja) * | 2003-09-05 | 2011-04-06 | 富山化学工業株式会社 | 新規なベンズアミジン誘導体またはその塩 |
| WO2019241566A1 (en) * | 2018-06-14 | 2019-12-19 | Georgia State University Research Foundation, Inc. | Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2277862A (en) * | 1938-12-05 | 1942-03-31 | May & Baker Ltd | Process for the preparation of diamidine derivatives |
| US2449724A (en) * | 1945-07-11 | 1948-09-21 | Short Wallace Frank | Manufacture of amidines |
| US3105853A (en) * | 1959-11-30 | 1963-10-01 | Monsanto Canada Ltd | Bis |
-
1976
- 1976-01-13 JP JP51002458A patent/JPS5922697B2/ja not_active Expired
- 1976-09-22 US US05/725,673 patent/US4034010A/en not_active Expired - Lifetime
- 1976-09-24 GB GB39861/76A patent/GB1559983A/en not_active Expired
- 1976-09-24 DE DE19762643090 patent/DE2643090A1/de not_active Ceased
- 1976-09-24 FR FR7628826A patent/FR2338039A1/fr active Granted
-
1977
- 1977-04-14 US US05/787,462 patent/US4064169A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2338039A1 (fr) | 1977-08-12 |
| US4034010A (en) | 1977-07-05 |
| JPS5287135A (en) | 1977-07-20 |
| GB1559983A (en) | 1980-01-30 |
| JPS5922697B2 (ja) | 1984-05-28 |
| US4064169A (en) | 1977-12-20 |
| DE2643090A1 (de) | 1977-07-21 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |