FR2327792A1 - Sels de bismuth insolubles du type de ceux utilises en therapeutique et procede pour leur obtention - Google Patents
Sels de bismuth insolubles du type de ceux utilises en therapeutique et procede pour leur obtentionInfo
- Publication number
- FR2327792A1 FR2327792A1 FR7531961A FR7531961A FR2327792A1 FR 2327792 A1 FR2327792 A1 FR 2327792A1 FR 7531961 A FR7531961 A FR 7531961A FR 7531961 A FR7531961 A FR 7531961A FR 2327792 A1 FR2327792 A1 FR 2327792A1
- Authority
- FR
- France
- Prior art keywords
- water
- neurotoxicity
- prepn
- solvents
- free
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010029350 Neurotoxicity Diseases 0.000 title 1
- 206010044221 Toxic encephalopathy Diseases 0.000 title 1
- 150000001621 bismuth Chemical class 0.000 title 1
- 239000002904 solvent Substances 0.000 title 1
- 238000005406 washing Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 229910052797 bismuth Inorganic materials 0.000 abstract 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical class [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 abstract 1
- 229940036348 bismuth carbonate Drugs 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- GMZOPRQQINFLPQ-UHFFFAOYSA-H dibismuth;tricarbonate Chemical compound [Bi+3].[Bi+3].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O GMZOPRQQINFLPQ-UHFFFAOYSA-H 0.000 abstract 1
- PPNKDDZCLDMRHS-UHFFFAOYSA-N dinitrooxybismuthanyl nitrate Chemical class [Bi+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O PPNKDDZCLDMRHS-UHFFFAOYSA-N 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 231100001096 no neurotoxicity Toxicity 0.000 abstract 1
- QGWDKKHSDXWPET-UHFFFAOYSA-E pentabismuth;oxygen(2-);nonahydroxide;tetranitrate Chemical compound [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-2].[Bi+3].[Bi+3].[Bi+3].[Bi+3].[Bi+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O QGWDKKHSDXWPET-UHFFFAOYSA-E 0.000 abstract 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 abstract 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/245—Bismuth; Compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G29/00—Compounds of bismuth
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2006/00—Physical properties of inorganic compounds
- C01P2006/90—Other properties not specified above
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7531961A FR2327792A1 (fr) | 1975-10-17 | 1975-10-17 | Sels de bismuth insolubles du type de ceux utilises en therapeutique et procede pour leur obtention |
| NL7611457A NL7611457A (nl) | 1975-10-17 | 1976-10-15 | Onoplosbare bismutzouten, de bereiding ervan, alsmede farmaceutische preparaten. |
| BE171573A BE847363A (fr) | 1975-10-17 | 1976-10-15 | Sels de bismuth insolubles du type de ceux utilises en therapeutique et procede pour leur obtention, |
| JP12475376A JPS5287217A (en) | 1975-10-17 | 1976-10-18 | Insoluble bismuth sact for treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7531961A FR2327792A1 (fr) | 1975-10-17 | 1975-10-17 | Sels de bismuth insolubles du type de ceux utilises en therapeutique et procede pour leur obtention |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2327792A1 true FR2327792A1 (fr) | 1977-05-13 |
| FR2327792B1 FR2327792B1 (enExample) | 1979-09-14 |
Family
ID=9161371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7531961A Granted FR2327792A1 (fr) | 1975-10-17 | 1975-10-17 | Sels de bismuth insolubles du type de ceux utilises en therapeutique et procede pour leur obtention |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5287217A (enExample) |
| BE (1) | BE847363A (enExample) |
| FR (1) | FR2327792A1 (enExample) |
| NL (1) | NL7611457A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2195292C1 (ru) * | 2001-11-29 | 2002-12-27 | Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" | Фармацевтическая композиция, обладающая противоязвенным и антацидным действием |
-
1975
- 1975-10-17 FR FR7531961A patent/FR2327792A1/fr active Granted
-
1976
- 1976-10-15 BE BE171573A patent/BE847363A/xx unknown
- 1976-10-15 NL NL7611457A patent/NL7611457A/xx not_active Application Discontinuation
- 1976-10-18 JP JP12475376A patent/JPS5287217A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2195292C1 (ru) * | 2001-11-29 | 2002-12-27 | Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" | Фармацевтическая композиция, обладающая противоязвенным и антацидным действием |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2327792B1 (enExample) | 1979-09-14 |
| BE847363A (fr) | 1977-04-15 |
| NL7611457A (nl) | 1977-04-19 |
| JPS5287217A (en) | 1977-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |