FR2320742A1 - Derives pyrroliniques et leur application pharmacologique - Google Patents
Derives pyrroliniques et leur application pharmacologiqueInfo
- Publication number
- FR2320742A1 FR2320742A1 FR7624483A FR7624483A FR2320742A1 FR 2320742 A1 FR2320742 A1 FR 2320742A1 FR 7624483 A FR7624483 A FR 7624483A FR 7624483 A FR7624483 A FR 7624483A FR 2320742 A1 FR2320742 A1 FR 2320742A1
- Authority
- FR
- France
- Prior art keywords
- pyrrolinic
- derivatives
- reacting
- pharmacological application
- meso2cl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000000144 pharmacologic effect Effects 0.000 title 1
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 2
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 2
- -1 3-pyrrolin-1-yl Chemical group 0.000 abstract 1
- 241000700159 Rattus Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001143 conditioned effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- YDBONCLBTWFUPF-UHFFFAOYSA-N ethyl 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetate Chemical compound CCOC(=O)CN1CC(O)CC1=O YDBONCLBTWFUPF-UHFFFAOYSA-N 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- QARBMVPHQWIHKH-UHFFFAOYSA-N methanesulfonyl chloride Chemical compound CS(Cl)(=O)=O QARBMVPHQWIHKH-UHFFFAOYSA-N 0.000 abstract 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 abstract 1
- 230000011514 reflex Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Detergent Compositions (AREA)
- Coloring (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2632775 | 1975-08-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2320742A1 true FR2320742A1 (fr) | 1977-03-11 |
Family
ID=11219236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7624483A Withdrawn FR2320742A1 (fr) | 1975-08-13 | 1976-08-11 | Derives pyrroliniques et leur application pharmacologique |
Country Status (19)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITUA20161346A1 (it) * | 2016-03-04 | 2017-09-04 | Univ Degli Studi Di Parma | Uso di derivati 2-oxo-2h-pirrol-1(5h)-carbossamidici come agenti anti-hiv e processo per la loro produzione |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1075564B (it) | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| IT1075280B (it) | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| HU195773B (en) * | 1985-09-24 | 1988-07-28 | Lonza Ag | Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid |
| IL80071A0 (en) * | 1985-09-24 | 1986-12-31 | Lonza Ag | Pyrrolidine acetamide derivatives |
| CH668067A5 (de) * | 1986-05-14 | 1988-11-30 | Lonza Ag | 4-alkoxy-3-pyrrolin-2-on-1-yl-essigsaeureamide, deren herstellung und verwendung. |
| CN112876397B (zh) * | 2021-01-19 | 2022-03-18 | 江苏诚信药业有限公司 | 一种2,5-二氢-2-氧代-1h-吡咯-1-乙酰胺的制备方法 |
-
1976
- 1976-08-09 IN IN1434/CAL/76A patent/IN141326B/en unknown
- 1976-08-09 NZ NZ181727A patent/NZ181727A/xx unknown
- 1976-08-09 AR AR264271A patent/AR211398Q/es unknown
- 1976-08-10 DE DE19762635854 patent/DE2635854A1/de active Pending
- 1976-08-10 PT PT65459A patent/PT65459B/pt unknown
- 1976-08-10 YU YU01965/76A patent/YU196576A/xx unknown
- 1976-08-10 SE SE7608939A patent/SE7608939L/xx unknown
- 1976-08-10 PT PT65460A patent/PT65460B/pt unknown
- 1976-08-11 DD DD194288A patent/DD126509A5/xx unknown
- 1976-08-11 NO NO762792A patent/NO762792L/no unknown
- 1976-08-11 BE BE6045635A patent/BE845100A/xx unknown
- 1976-08-11 CH CH1022676A patent/CH602637A5/xx not_active IP Right Cessation
- 1976-08-11 NL NL7608947A patent/NL7608947A/xx not_active Application Discontinuation
- 1976-08-11 FR FR7624483A patent/FR2320742A1/fr not_active Withdrawn
- 1976-08-11 JP JP51095929A patent/JPS5223071A/ja active Pending
- 1976-08-12 SU SU762388412A patent/SU674671A3/ru active
- 1976-08-12 DK DK365276A patent/DK365276A/da unknown
- 1976-08-12 ES ES450644A patent/ES450644A1/es not_active Expired
- 1976-08-12 AU AU16798/76A patent/AU1679876A/en not_active Expired
- 1976-08-12 FI FI762313A patent/FI762313A7/fi not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITUA20161346A1 (it) * | 2016-03-04 | 2017-09-04 | Univ Degli Studi Di Parma | Uso di derivati 2-oxo-2h-pirrol-1(5h)-carbossamidici come agenti anti-hiv e processo per la loro produzione |
| WO2017149511A1 (en) * | 2016-03-04 | 2017-09-08 | Universita' Degli Studi Di Parma | Use of 2-oxo-2h-pyrrol-1(5h)-carboxamide derivatives as anti-hiv agents and process for the production thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| YU196576A (en) | 1982-05-31 |
| ES450644A1 (es) | 1977-07-16 |
| IN141326B (enrdf_load_stackoverflow) | 1977-02-12 |
| JPS5223071A (en) | 1977-02-21 |
| AR211398Q (es) | 1977-12-15 |
| NZ181727A (en) | 1978-03-06 |
| SE7608939L (sv) | 1977-02-14 |
| DK365276A (da) | 1977-02-14 |
| NO762792L (enrdf_load_stackoverflow) | 1977-02-15 |
| PT65459A (en) | 1976-09-01 |
| DD126509A5 (enrdf_load_stackoverflow) | 1977-07-20 |
| SU674671A3 (ru) | 1979-07-15 |
| BE845100A (fr) | 1977-02-11 |
| CH602637A5 (enrdf_load_stackoverflow) | 1978-07-31 |
| DE2635854A1 (de) | 1977-02-24 |
| AU1679876A (en) | 1978-02-16 |
| PT65460A (en) | 1976-09-01 |
| PT65459B (en) | 1978-07-03 |
| FI762313A7 (enrdf_load_stackoverflow) | 1977-02-14 |
| NL7608947A (nl) | 1977-02-15 |
| PT65460B (en) | 1978-07-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR6240890D0 (pt) | Preparacao de n-(tercio amino alquil)benzamidas substituidas | |
| SE408992B (sv) | Fullstendig engangsbloja med sammandragbara sidodelar | |
| SE7806519L (sv) | Terapeutiska medel | |
| SE425971B (sv) | Optiskt aktiv mellanprodukt med absolut (s)-konfiguration till anvendning for framstellning av (s)-1-fenyloxi-3-amino-propanolderivat med beta-adrenergisk blockeringsaktivitet | |
| FR2320742A1 (fr) | Derives pyrroliniques et leur application pharmacologique | |
| AR209297A1 (es) | Nuevos derivados de anilina n-(1'-metoxicarbonil-etil) -n- halogenoacetil -2,6- disustituida su preparacion y su utilizacion como microbicidas | |
| SE423544B (sv) | Analogiforfarande for framstellning av imidazolderivat med antifungisk aktivitet | |
| NO148524C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive heterocykliske derivater av guanidin | |
| AR204390A1 (es) | Procedimiento de preparacion de derivados de imidazolidinonas y perhidropirimidinonas n,n' bisustituidas | |
| AR217226A1 (es) | Nuevos derivados de n-(3-metil-tio propil)urea | |
| BE609074R (fr) | Procédé de préparation de dérivés N-substitués d'amino-norcamphane à activité analeptique | |
| FI45660C (fi) | Menetelmä terapeuttisesti käytettävien D-6-metyyli- ja D-1,6-dimetyyli -8-aminometyyli-ergoliini I N-asyyli-johdannaisten valmistamiseksi. | |
| FR93884E (fr) | Dérivés amidés d'acides halogéno et nitro benzoiques et leur préparation. | |
| FR1282518A (fr) | Dérivés nu-acylés d'acides (3.5-diamino-2. 4. 6-tri-iodo-benzoyl)-aminés | |
| FR2276M (fr) | Amides de dérivés 2-(aminométhyle) d'oxydes de polyméthylene. | |
| FR1228455A (fr) | émulsions aqueuses stables de polymères réticulables par oxydation | |
| FR1323062A (fr) | Dérivés d'acides fluorène-sulfoniques | |
| FR2078729A5 (en) | Herbicidal 2,4-bis-trifluoromethyl-6-nitro-anilines | |
| FR1514517A (fr) | Procédé de préparation de dérivés de n-substitués benzamides | |
| FR1178229A (fr) | Nouveaux dérivés de l'urée et leur préparation | |
| FR3482M (fr) | Applications pharmacologiques de la 6-amino-4-prégnene-3,20-dione et de ses dérivés n-acylés comme agents anesthésiques. | |
| SE399555B (sv) | Mellanprodukter for framstellning av 4-aminoamfetaminderivat med terapeutisk aktivitet | |
| FR71259E (fr) | Dérivés n-substitués d'hydroxyalcoyl phénothiazines et leur préparation | |
| FR1291887A (fr) | Nouveaux dérivés pentafluorophényliques de l'urée et de la thiourée | |
| FR1372419A (fr) | Dérivés n-substitués de la pipérazine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |