FR2320109A1 - Analogues de somatostatine - Google Patents

Analogues de somatostatine

Info

Publication number
FR2320109A1
FR2320109A1 FR7623935A FR7623935A FR2320109A1 FR 2320109 A1 FR2320109 A1 FR 2320109A1 FR 7623935 A FR7623935 A FR 7623935A FR 7623935 A FR7623935 A FR 7623935A FR 2320109 A1 FR2320109 A1 FR 2320109A1
Authority
FR
France
Prior art keywords
somatostatin analogues
somatostatin
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7623935A
Other languages
English (en)
Other versions
FR2320109B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2320109A1 publication Critical patent/FR2320109A1/fr
Application granted granted Critical
Publication of FR2320109B1 publication Critical patent/FR2320109B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7623935A 1975-08-08 1976-08-05 Analogues de somatostatine Granted FR2320109A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60306775A 1975-08-08 1975-08-08
US68000576A 1976-04-23 1976-04-23

Publications (2)

Publication Number Publication Date
FR2320109A1 true FR2320109A1 (fr) 1977-03-04
FR2320109B1 FR2320109B1 (fr) 1979-05-25

Family

ID=27084324

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7623935A Granted FR2320109A1 (fr) 1975-08-08 1976-08-05 Analogues de somatostatine

Country Status (8)

Country Link
JP (1) JPS5219659A (fr)
CH (1) CH626328A5 (fr)
DE (1) DE2635558A1 (fr)
DK (1) DK328876A (fr)
FR (1) FR2320109A1 (fr)
GB (1) GB1502573A (fr)
NL (1) NL7607987A (fr)
SE (1) SE419440B (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002264A1 (fr) * 1977-12-01 1979-06-13 Merck & Co. Inc. Analogues de la somatostatine, leur procédé de préparation et leur composition pharmaceutique
EP0002262A1 (fr) * 1977-12-01 1979-06-13 Merck & Co. Inc. Analogues de la somatostatine et leur procédé de préparation
WO1993003056A1 (fr) * 1991-08-09 1993-02-18 Winfried Kolbeck Peptides relies par des ponts lanthionine
WO1994000489A2 (fr) * 1992-06-23 1994-01-06 Diatech, Inc. Peptides derives de la somatostatine et marques de maniere radioactive pour imagerie et utilisations therapeutiques
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US6017509A (en) * 1991-11-27 2000-01-25 Diatide, Inc. Radiolabeled somatostatin receptor-binding peptides
US6241965B1 (en) 1993-07-21 2001-06-05 Diatide, Inc. Somatostatin derivatives and their radiolabelled products

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115554A (en) * 1977-08-29 1978-09-19 Merck & Co., Inc. Somatostatin analogs
LU78191A1 (de) * 1977-09-28 1979-05-25 Ciba Geigy Ag Verfahren zur herstellung von neuen cyclopeptiden
JPS5819669B2 (ja) * 1978-10-28 1983-04-19 白井松新薬株式会社 新規生理活性ペプチド化合物及びその製造法
US4316890A (en) * 1979-03-16 1982-02-23 Ciba-Geigy Corporation Peptides and processes for the manufacture thereof
US4244947A (en) * 1979-08-13 1981-01-13 Ayerst Mckenna And Harrison Inc. Carba decapeptide derivatives of [TYR6 ]-somatostatin
NL8701143A (nl) * 1986-05-27 1987-12-16 Sandoz Ag Farmaceutische preparaten.
EP1231919B1 (fr) 1999-09-08 2015-09-30 Sloan-Kettering Institute For Cancer Research Derivés de 1-amino-1-(hétero)arylaminocarbonyl-6-hydroxyaminocarbonylhexan utiles dans le traitement de tumeurs

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3446789A (en) * 1964-07-27 1969-05-27 Ceskoslovenska Akademie Ved Analogues of cyclic peptides containing disulfide bonds without disulfide bonds
DE2460469A1 (de) * 1974-12-20 1976-07-01 Hoechst Ag Neue peptide mit biologischer wirkung und verfahren zu ihrer herstellung

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3446789A (en) * 1964-07-27 1969-05-27 Ceskoslovenska Akademie Ved Analogues of cyclic peptides containing disulfide bonds without disulfide bonds
DE2460469A1 (de) * 1974-12-20 1976-07-01 Hoechst Ag Neue peptide mit biologischer wirkung und verfahren zu ihrer herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, EDIT. CHEMICAL ABSTRACTS SERVICE, OHIO, VOLUME 80, REFERENCE No. 15183N, 1974, CITE & BIOCHEM. BIOPHYS. RES. COMMUN. 1973, 54, 4, PAGES 1267-1273 *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002262A1 (fr) * 1977-12-01 1979-06-13 Merck & Co. Inc. Analogues de la somatostatine et leur procédé de préparation
EP0002264A1 (fr) * 1977-12-01 1979-06-13 Merck & Co. Inc. Analogues de la somatostatine, leur procédé de préparation et leur composition pharmaceutique
AU664855B2 (en) * 1991-08-09 1995-12-07 Winfried Kolbeck Lanthionine bridged peptides
WO1993003056A1 (fr) * 1991-08-09 1993-02-18 Winfried Kolbeck Peptides relies par des ponts lanthionine
US6017509A (en) * 1991-11-27 2000-01-25 Diatide, Inc. Radiolabeled somatostatin receptor-binding peptides
US5814298A (en) * 1992-06-23 1998-09-29 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
WO1994000489A3 (fr) * 1992-06-23 1994-03-31 Diatech Inc Peptides derives de la somatostatine et marques de maniere radioactive pour imagerie et utilisations therapeutiques
US5820845A (en) * 1992-06-23 1998-10-13 Diatide, Inc. Somatostatin-derived peptides for imaging and therapeutic uses
US5833942A (en) * 1992-06-23 1998-11-10 Diatide, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging and therapeutic uses
US5843401A (en) * 1992-06-23 1998-12-01 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
WO1994000489A2 (fr) * 1992-06-23 1994-01-06 Diatech, Inc. Peptides derives de la somatostatine et marques de maniere radioactive pour imagerie et utilisations therapeutiques
US6241965B1 (en) 1993-07-21 2001-06-05 Diatide, Inc. Somatostatin derivatives and their radiolabelled products

Also Published As

Publication number Publication date
JPS5219659A (en) 1977-02-15
SE7608300L (sv) 1977-02-09
GB1502573A (en) 1978-03-01
DK328876A (da) 1977-02-09
SE419440B (sv) 1981-08-03
NL7607987A (nl) 1977-02-10
DE2635558A1 (de) 1977-02-17
FR2320109B1 (fr) 1979-05-25
CH626328A5 (en) 1981-11-13

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Legal Events

Date Code Title Description
ST Notification of lapse