BE868202A - Analogues de prostacycline - Google Patents

Analogues de prostacycline

Info

Publication number
BE868202A
BE868202A BE188638A BE188638A BE868202A BE 868202 A BE868202 A BE 868202A BE 188638 A BE188638 A BE 188638A BE 188638 A BE188638 A BE 188638A BE 868202 A BE868202 A BE 868202A
Authority
BE
Belgium
Prior art keywords
prostacycline
analogues
prostacycline analogues
Prior art date
Application number
BE188638A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BE868202A publication Critical patent/BE868202A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BE188638A 1977-06-17 1978-06-16 Analogues de prostacycline BE868202A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/807,514 US4097489A (en) 1977-06-17 1977-06-17 9-Deoxy-9α,6-nitrilo or 6,9α-imino-PGF compounds

Publications (1)

Publication Number Publication Date
BE868202A true BE868202A (fr) 1978-12-18

Family

ID=25196557

Family Applications (1)

Application Number Title Priority Date Filing Date
BE188638A BE868202A (fr) 1977-06-17 1978-06-16 Analogues de prostacycline

Country Status (16)

Country Link
US (6) US4097489A (fr)
JP (1) JPS549265A (fr)
AU (1) AU520091B2 (fr)
BE (1) BE868202A (fr)
CA (1) CA1091227A (fr)
CH (1) CH635075A5 (fr)
DE (1) DE2826096A1 (fr)
FR (1) FR2394530A1 (fr)
GB (1) GB1598137A (fr)
IE (1) IE47199B1 (fr)
IL (1) IL54806A (fr)
IT (1) IT1158739B (fr)
NL (1) NL7806383A (fr)
NZ (1) NZ187393A (fr)
SE (1) SE7806927L (fr)
ZA (1) ZA783065B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4097489A (en) * 1977-06-17 1978-06-27 The Upjohn Company 9-Deoxy-9α,6-nitrilo or 6,9α-imino-PGF compounds
JPS54125653A (en) * 1978-03-18 1979-09-29 Ono Pharmaceut Co Ltd Prostaglandin i2 analog, its preparation, and drug composition comprising it as active constituent
US4211706A (en) * 1978-10-13 1980-07-08 The Upjohn Company 9-Deoxy-9α,6-nitrilo or 6,9α-imino-17,18-didehydro-PGF compounds
DE2845770A1 (de) * 1978-10-19 1980-04-30 Schering Ag Neue prostacyclin-derivate und verfahren zu ihrer herstellung
DE2907118A1 (de) * 1979-02-20 1980-09-04 Schering Ag Neue prostacyclin-derivate und verfahren zu ihrer herstellung
JPS55111465A (en) * 1979-02-20 1980-08-28 Ono Pharmaceut Co Ltd Prostaglandin i2 analog and its preparation
US4294759A (en) * 1979-11-15 1981-10-13 The Upjohn Company Structural analogues of 5,6,-dihydro PG1
JPS56111811A (en) * 1980-02-11 1981-09-03 Toshiba Corp Light signal branching device
DE3006865A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Hetero-imino-prostacycline
DE3176313D1 (en) * 1980-12-09 1987-08-20 Teijin Ltd Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
DE3107100A1 (de) * 1981-02-20 1982-09-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Azaprostacycline, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung
NZ200210A (en) * 1981-04-02 1985-10-11 Searle & Co Prostacyclin pgi2 derivatives and pharmaceutical compositions
US4702261A (en) * 1985-07-03 1987-10-27 Sherwood Medical Company Biopsy device and method
US6187813B1 (en) 1990-04-10 2001-02-13 Pharmacia & Upjohn Aktiebolag Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
EP0569046B1 (fr) 1988-09-06 2002-11-13 Pharmacia Aktiebolag Dérivés de prostaglandine pour traitement du glaucome ou hypertension oculaire
US5972991A (en) * 1992-09-21 1999-10-26 Allergan Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
CA2146127C (fr) * 1992-10-13 2000-06-13 Louis Desantis, Jr. Associations de prostaglandines et de derives de la clonidine pour le traitement du glaucome
US5332730A (en) * 1992-10-16 1994-07-26 Allergan, Inc. Azido derivatives of cyclopentane heptanoic or heptenoic acid
US6294563B1 (en) 1994-10-27 2001-09-25 Allergan Sales, Inc. Combinations of prostaglandins and brimonidine or derivatives thereof
US5700835A (en) * 1995-12-22 1997-12-23 Alcon Laboratories, Inc. 3-Oxa-D-prostaglandins for lowering IOP
AU7680096A (en) * 1995-12-22 1997-07-17 Alcon Laboratories, Inc. Combinations of dp and fp type prostaglandins for lowering iop
US7718697B2 (en) * 2003-12-17 2010-05-18 Alcon, Inc. Method for treating glaucoma comprising administering α-lipoic acid

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931289A (en) * 1970-12-31 1976-01-06 The Upjohn Company 3-Oxa phenyl-substituted PGE compounds
US3772312A (en) * 1972-01-31 1973-11-13 Ciba Geigy Corp Octahydropyrindenes
US3983157A (en) * 1974-04-11 1976-09-28 The Upjohn Company 4-Oxa phenyl-substituted PGF compounds
US3983158A (en) * 1974-04-11 1976-09-28 The Upjohn Company 3-Oxa phenyl-substituted PGA compounds
US4324905A (en) * 1974-08-14 1982-04-13 The Upjohn Company Phenacyl-type esters of PGF2α and its 15-methyl analogs
GB1529852A (en) * 1975-03-21 1978-10-25 Labaz 8-azaprostaglandins and process for the preparation thereof
GB1523178A (en) * 1975-04-26 1978-08-31 Tanabe Seiyaku Co 8-azaprostanoic acid derivatives and process for preparing the same
US3983178A (en) * 1975-07-21 1976-09-28 Hooker Chemicals & Plastics Corporation Immonium salts and derivatives thereof
US4097489A (en) * 1977-06-17 1978-06-27 The Upjohn Company 9-Deoxy-9α,6-nitrilo or 6,9α-imino-PGF compounds

Also Published As

Publication number Publication date
AU520091B2 (en) 1982-01-14
ZA783065B (en) 1979-06-27
NL7806383A (nl) 1978-12-19
FR2394530B1 (fr) 1981-02-27
US4097489A (en) 1978-06-27
SE7806927L (sv) 1979-12-16
JPS549265A (en) 1979-01-24
DE2826096A1 (de) 1979-01-04
IL54806A (en) 1984-02-29
NZ187393A (en) 1981-12-15
US4163841A (en) 1979-08-07
CH635075A5 (de) 1983-03-15
GB1598137A (en) 1981-09-16
AU3655778A (en) 1979-12-06
IE47199B1 (en) 1984-01-11
FR2394530A1 (fr) 1979-01-12
US4161584A (en) 1979-07-17
IE781222L (en) 1978-12-17
IT1158739B (it) 1987-02-25
CA1091227A (fr) 1980-12-09
US4152514A (en) 1979-05-01
US4151176A (en) 1979-04-24
IT7824093A0 (it) 1978-05-31
US4136095A (en) 1979-01-23

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: THE UPJOHN CY

Effective date: 19870630