FR2316950A1 - Nouveaux derives anhydro d'alcaloides de vinca - Google Patents

Nouveaux derives anhydro d'alcaloides de vinca

Info

Publication number
FR2316950A1
FR2316950A1 FR7620860A FR7620860A FR2316950A1 FR 2316950 A1 FR2316950 A1 FR 2316950A1 FR 7620860 A FR7620860 A FR 7620860A FR 7620860 A FR7620860 A FR 7620860A FR 2316950 A1 FR2316950 A1 FR 2316950A1
Authority
FR
France
Prior art keywords
new
vinca alkaloids
anhydro derivatives
anhydro
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7620860A
Other languages
English (en)
Other versions
FR2316950B1 (fr
Inventor
Gerald Edward Gutowski
Jean Coronne Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C Van der Lely NV
Original Assignee
C Van der Lely NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C Van der Lely NV filed Critical C Van der Lely NV
Publication of FR2316950A1 publication Critical patent/FR2316950A1/fr
Application granted granted Critical
Publication of FR2316950B1 publication Critical patent/FR2316950B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR7620860A 1975-07-10 1976-07-08 Nouveaux derives anhydro d'alcaloides de vinca Granted FR2316950A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/594,915 US4029663A (en) 1975-07-10 1975-07-10 Dimeric anhydro-vinca derivatives

Publications (2)

Publication Number Publication Date
FR2316950A1 true FR2316950A1 (fr) 1977-02-04
FR2316950B1 FR2316950B1 (fr) 1980-10-17

Family

ID=24380952

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7620860A Granted FR2316950A1 (fr) 1975-07-10 1976-07-08 Nouveaux derives anhydro d'alcaloides de vinca

Country Status (12)

Country Link
US (1) US4029663A (fr)
JP (1) JPS5210300A (fr)
BE (1) BE843950A (fr)
CA (1) CA1057750A (fr)
CH (1) CH625530A5 (fr)
DE (1) DE2630392A1 (fr)
FR (1) FR2316950A1 (fr)
GB (1) GB1548621A (fr)
HU (1) HU179457B (fr)
IE (1) IE43113B1 (fr)
IL (1) IL49706A (fr)
NL (1) NL7607549A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2438659A1 (fr) * 1978-10-10 1980-05-09 Lilly Co Eli Procede de preparation du sulfate de vindesine

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (fr) * 1974-12-30 1978-07-21 Anvar
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
US4160767A (en) * 1976-12-06 1979-07-10 Eli Lilly And Company Vinca alkaloid intermediates
USRE30561E (en) * 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4143041A (en) * 1977-01-19 1979-03-06 Eli Lilly And Company 4'-Deoxyvincristine and related compounds
US4166810A (en) * 1978-04-20 1979-09-04 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
US4639456A (en) * 1980-06-10 1987-01-27 Omnichem S.A. Vinblastin-23-oyl amino acid derivatives
US4322351A (en) * 1980-08-25 1982-03-30 Eli Lilly And Company Antineoplastic 4'-formylamino and 4'-acetylamino VLB, and derivatives thereof
US4320058A (en) * 1980-12-29 1982-03-16 Eli Lilly And Company 20'-Hydroxyvinblastine and related compounds
HU185691B (en) * 1982-02-09 1985-03-28 Richter Gedeon Vegyeszet Process for preparing a new analgetic pharmaceutical composition
US4596676A (en) * 1983-03-30 1986-06-24 Lilly Industries Limited Bifunctional ester derivatives of 4-desacetyl indole-dihydroindole alkaloids
HU193772B (en) * 1985-06-12 1987-11-30 Richter Gedeon Vegyeszet Process for producing new nitro-bis-indole derivatives
US6011041A (en) * 1995-07-28 2000-01-04 University Of British Columbia Use of anhydrovinblastine
AU783029B2 (en) * 1997-03-04 2005-09-15 University Of British Columbia, The Anhydrovinblastine for the treatment of cervical and lung cancer
US20030162803A1 (en) * 1997-03-04 2003-08-28 Bruce Schmidt Anhydrovinblastine for the treatment of cancer
CA2219095A1 (fr) 1997-03-04 1998-09-04 Bruce Schmidt Anhydro-vinblastine pour le traitement du cancer du col uterin et du cancer du poumon
US6841538B1 (en) 1998-04-22 2005-01-11 Inex Pharmaceuticals Corporation Combination therapy using nucleic acids and radio therapy
CA2325561A1 (fr) * 1998-04-22 1999-10-28 Inex Pharmaceuticals Corporation Traitement associe utilisant des acides nucleiques et des medicaments classiques
US6841537B1 (en) 1998-04-22 2005-01-11 Protiva Biotherapeutics Inc. Combination therapy using nucleic acids and conventional drugs
EP2289549A3 (fr) 1999-10-01 2011-06-15 Immunogen, Inc. Des immunoconjugués pour le traitement des cancers.
WO2005086922A2 (fr) * 2004-03-10 2005-09-22 Board Of Regents, University Of Texas System Adenovirus oncolytique dote de genes therapeutiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3097137A (en) * 1960-05-19 1963-07-09 Canadian Patents Dev Vincaleukoblastine
US3392173A (en) * 1964-03-09 1968-07-09 Lilly Co Eli Novel acyl derivatives of desacetyl-vincaleukoblastine and processes for their preparation
US3352868A (en) * 1964-04-01 1967-11-14 Lilly Co Eli Dihydrovinblastine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2438659A1 (fr) * 1978-10-10 1980-05-09 Lilly Co Eli Procede de preparation du sulfate de vindesine

Also Published As

Publication number Publication date
CA1057750A (fr) 1979-07-03
BE843950A (fr) 1977-01-10
US4029663A (en) 1977-06-14
IE43113L (en) 1977-01-10
FR2316950B1 (fr) 1980-10-17
GB1548621A (en) 1979-07-18
JPS6220192B2 (fr) 1987-05-06
IL49706A0 (en) 1976-08-31
IL49706A (en) 1979-09-30
DE2630392A1 (de) 1977-02-03
NL7607549A (nl) 1977-01-12
JPS5210300A (en) 1977-01-26
HU179457B (en) 1982-10-28
IE43113B1 (en) 1980-12-17
CH625530A5 (fr) 1981-09-30

Similar Documents

Publication Publication Date Title
BE843950A (fr) Nouveaux derives anhydro d'alcaloides de vinca
FR2320754A1 (fr) Nouveaux derives de n-((1-piperidinyl) alcoyl) arylcarboxamide
BE868532A (fr) Nouveaux derives de la thiazolidine
FR2342736A1 (fr) Nouveaux derives de diazepine
NL7613450A (nl) 3.4-dihydrochinazolinederivaten en werkwijzen ter bereiding ervan.
FR2316926A1 (fr) Nouveaux derives de bicycloheptenes
FR2298332A1 (fr) Nouveaux derives de 5-fluorouraciles
FR2348926A1 (fr) Nouveaux derives de l'adenine
FR2318635A1 (fr) Derives olefiniques de phenylpiperazines
FR2301253A1 (fr) Derives de la
FR2298328A1 (fr) Nouveaux derives d'imidazole
BE848962A (fr) Nouveaux derives de l'indazole
FR2307524A1 (fr) Nouveaux derives de benzophenone
FR2323691A1 (fr) Nouveaux derives de 1,2-benzisoxazole et leur preparation
FR2322604A1 (fr) Derives 3-triazolylthio d'ureido-7a-methoxy-ou demethoxycephalosporines
FR2313074A1 (fr) Diastereoisomeres de derives phenylaminoethanol
BE837341A (fr) Nouveaux derives de morpholine et leur preparation
BE859439A (fr) Nouveaux derives de piperazine
BE845100A (fr) Derives pyrroliniques et leur application pharmacologique
FR2332990A1 (fr) Preparation de derives d'ethylamine
BE866933A (fr) Nouveaux derives de fortmicine
BE838878A (fr) Nouveaux derives de protaglandines et leur preparation
FR2301249A1 (fr) Derives du 3-amino-4-carbamyl-pyrrole et leur preparation
FR2328470A1 (fr) Nouveaux derives de la bicyclomycine
BE851463A (fr) Nouveaux derives d'indolizine

Legal Events

Date Code Title Description
ST Notification of lapse