FR2313933A1 - Procede d'obtention de ni-(21-furanidil)-3-uraciles substitue - Google Patents
Procede d'obtention de ni-(21-furanidil)-3-uraciles substitueInfo
- Publication number
- FR2313933A1 FR2313933A1 FR7518273A FR7518273A FR2313933A1 FR 2313933 A1 FR2313933 A1 FR 2313933A1 FR 7518273 A FR7518273 A FR 7518273A FR 7518273 A FR7518273 A FR 7518273A FR 2313933 A1 FR2313933 A1 FR 2313933A1
- Authority
- FR
- France
- Prior art keywords
- dihydrofuran
- bis
- reacting
- tetrahydrofuranyl
- trimethylsilyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JKTCBAGSMQIFNL-UHFFFAOYSA-N 2,3-dihydrofuran Chemical compound C1CC=CO1 JKTCBAGSMQIFNL-UHFFFAOYSA-N 0.000 title abstract 2
- ALBNIGFLZXAYBX-UHFFFAOYSA-N 3-(oxolan-2-yl)-1h-pyrimidine-2,4-dione Chemical compound O=C1C=CNC(=O)N1C1OCCC1 ALBNIGFLZXAYBX-UHFFFAOYSA-N 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title 1
- FSBNTQRWSOTNEW-UHFFFAOYSA-N Pyrimidine, 2,4- bis[(trimethylsilyl)oxy]- Chemical compound C[Si](C)(C)OC1=CC=NC(O[Si](C)(C)C)=N1 FSBNTQRWSOTNEW-UHFFFAOYSA-N 0.000 title 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 title 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 title 1
- WFWLQNSHRPWKFK-UHFFFAOYSA-N Tegafur Chemical compound O=C1NC(=O)C(F)=CN1C1OCCC1 WFWLQNSHRPWKFK-UHFFFAOYSA-N 0.000 abstract 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000340 anti-metabolite Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 229940100197 antimetabolite Drugs 0.000 abstract 1
- 239000002256 antimetabolite Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 229940035893 uracil Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7518273A FR2313933A1 (fr) | 1975-06-11 | 1975-06-11 | Procede d'obtention de ni-(21-furanidil)-3-uraciles substitue |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7518273A FR2313933A1 (fr) | 1975-06-11 | 1975-06-11 | Procede d'obtention de ni-(21-furanidil)-3-uraciles substitue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2313933A1 true FR2313933A1 (fr) | 1977-01-07 |
| FR2313933B1 FR2313933B1 (enExample) | 1978-12-15 |
Family
ID=9156368
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7518273A Granted FR2313933A1 (fr) | 1975-06-11 | 1975-06-11 | Procede d'obtention de ni-(21-furanidil)-3-uraciles substitue |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2313933A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE31382E (en) * | 1977-03-10 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Static charge neutralizer and process |
-
1975
- 1975-06-11 FR FR7518273A patent/FR2313933A1/fr active Granted
Non-Patent Citations (2)
| Title |
|---|
| J. HET. CHEM. 1972, VOL. 9 5 , PAGES 1141-3 * |
| SOVIET INVENTIONS ILLUSTRATED, SEPTEMBRE 1971, 3, PHARMAC, PAGE 5.) * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE31382E (en) * | 1977-03-10 | 1983-09-13 | E. I. Du Pont De Nemours And Company | Static charge neutralizer and process |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2313933B1 (enExample) | 1978-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |