FR2310986A2 - D-Carbamylamino acids and D-amino acids useful as intermediates - prepd. by enzymic hydrolysis of substd. phenyl hydantoin and opt. further hydrolysis - Google Patents

D-Carbamylamino acids and D-amino acids useful as intermediates - prepd. by enzymic hydrolysis of substd. phenyl hydantoin and opt. further hydrolysis

Info

Publication number
FR2310986A2
FR2310986A2 FR7614135A FR7614135A FR2310986A2 FR 2310986 A2 FR2310986 A2 FR 2310986A2 FR 7614135 A FR7614135 A FR 7614135A FR 7614135 A FR7614135 A FR 7614135A FR 2310986 A2 FR2310986 A2 FR 2310986A2
Authority
FR
France
Prior art keywords
hydrolysis
prepd
opt
intermediates
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7614135A
Other languages
French (fr)
Other versions
FR2310986B2 (en
Inventor
Francesco Cecere
Giuliano Galli
Gino Della Penna
Bruno Rappuoli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SnamProgetti SpA
Original Assignee
SnamProgetti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SnamProgetti SpA filed Critical SnamProgetti SpA
Publication of FR2310986A2 publication Critical patent/FR2310986A2/en
Application granted granted Critical
Publication of FR2310986B2 publication Critical patent/FR2310986B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety

Abstract

D-Carbamylamino acids and the corresp. D-amino acids are prepd. by enzymic hydrolysis of a cpd. of general formula: (where X=OH, hydrocarbyl, halogen, alkoxy, NO2 or carboxyl) at pH 8-9 and opt. then hydrolysing at b.pt. Enzymic hydrolysis is pref. carried out at 10-70 degrees C. The enzyme used is pref. hydropyrimidine-hydrolase derived from calves' liver. The products are useful as intermediates.
FR7614135A 1975-05-12 1976-05-11 D-Carbamylamino acids and D-amino acids useful as intermediates - prepd. by enzymic hydrolysis of substd. phenyl hydantoin and opt. further hydrolysis Granted FR2310986A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23202/75A IT1046399B (en) 1975-05-12 1975-05-12 PROCEDURE FOR THE PREPARATION OF D CARBAMY AMINO ACIDS AND THE CORRESPONDING D AMINO ACIDS

Publications (2)

Publication Number Publication Date
FR2310986A2 true FR2310986A2 (en) 1976-12-10
FR2310986B2 FR2310986B2 (en) 1978-09-01

Family

ID=11204838

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7614135A Granted FR2310986A2 (en) 1975-05-12 1976-05-11 D-Carbamylamino acids and D-amino acids useful as intermediates - prepd. by enzymic hydrolysis of substd. phenyl hydantoin and opt. further hydrolysis

Country Status (19)

Country Link
JP (1) JPS51139687A (en)
AU (1) AU502568B2 (en)
BE (1) BE841750A (en)
CA (1) CA1069844A (en)
CS (1) CS209871B2 (en)
DD (1) DD125069A6 (en)
DE (1) DE2621076B2 (en)
DK (1) DK208776A (en)
FR (1) FR2310986A2 (en)
GB (1) GB1506067A (en)
HU (1) HU178336B (en)
IT (1) IT1046399B (en)
LU (1) LU74912A1 (en)
NL (1) NL7605081A (en)
NO (1) NO149779C (en)
SE (1) SE7605429L (en)
SU (1) SU784761A3 (en)
YU (1) YU39038B (en)
ZA (1) ZA762783B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0175312A2 (en) * 1984-09-17 1986-03-26 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing optically active hydantoins
EP0775748A2 (en) 1995-11-23 1997-05-28 ENIRICERCHE S.p.A. Preparation of D-alpha-amino acids, using bacteria transformed with the carbamoylase-hydantoinase operon

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5344690A (en) * 1976-02-04 1978-04-21 Kanegafuchi Chem Ind Co Ltd Preparation of d-n-carbamylphenylglycine and its substituted derivatives
EP0001319A1 (en) * 1977-08-18 1979-04-04 Beecham Group Plc Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT987278B (en) * 1973-05-11 1975-02-20 Snam Progetti PROCEDURE FOR THE PREPARATION OF L CARBAMIL AMINO ACIDS AND THE CORRESPONDING L AMINO ACIDS

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0175312A2 (en) * 1984-09-17 1986-03-26 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing optically active hydantoins
EP0175312A3 (en) * 1984-09-17 1987-04-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing optically active hydantoins
US4812406A (en) * 1984-09-17 1989-03-14 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Process for preparing optically active hydantoins
EP0775748A2 (en) 1995-11-23 1997-05-28 ENIRICERCHE S.p.A. Preparation of D-alpha-amino acids, using bacteria transformed with the carbamoylase-hydantoinase operon

Also Published As

Publication number Publication date
NO149779C (en) 1984-06-20
DE2621076A1 (en) 1976-11-25
HU178336B (en) 1982-04-28
JPS576912B2 (en) 1982-02-08
AU1371376A (en) 1977-11-10
NL7605081A (en) 1976-11-16
NO761621L (en) 1976-11-15
AU502568B2 (en) 1979-08-02
JPS51139687A (en) 1976-12-02
LU74912A1 (en) 1977-07-11
CS209871B2 (en) 1981-12-31
DE2621076B2 (en) 1980-04-17
SE7605429L (en) 1976-11-13
SU784761A3 (en) 1980-11-30
YU118276A (en) 1982-02-28
CA1069844A (en) 1980-01-15
BE841750A (en) 1976-11-12
NO149779B (en) 1984-03-12
IT1046399B (en) 1980-06-30
DK208776A (en) 1976-11-13
DD125069A6 (en) 1977-03-30
ZA762783B (en) 1977-04-27
FR2310986B2 (en) 1978-09-01
YU39038B (en) 1984-02-29
GB1506067A (en) 1978-04-05

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