FR2426685A2 - DERIVATIVES OF THIAZOLIDINECARBOXYLIC ACIDS AND RELATED ACIDS, USEFUL AS ANTI-HYPERTENSION AGENTS - Google Patents

DERIVATIVES OF THIAZOLIDINECARBOXYLIC ACIDS AND RELATED ACIDS, USEFUL AS ANTI-HYPERTENSION AGENTS

Info

Publication number
FR2426685A2
FR2426685A2 FR7816377A FR7816377A FR2426685A2 FR 2426685 A2 FR2426685 A2 FR 2426685A2 FR 7816377 A FR7816377 A FR 7816377A FR 7816377 A FR7816377 A FR 7816377A FR 2426685 A2 FR2426685 A2 FR 2426685A2
Authority
FR
France
Prior art keywords
acids
derivatives
useful
thiazolidinecarboxylic
hypertension agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7816377A
Other languages
French (fr)
Other versions
FR2426685B2 (en
Inventor
Miguel Angel Ondetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/907,452 external-priority patent/US4192878A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2426685A2 publication Critical patent/FR2426685A2/en
Application granted granted Critical
Publication of FR2426685B2 publication Critical patent/FR2426685B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The substituted derivatives of thiazolidine- and thiazanecarboxylic acids and of other similar acids having the formula are effective as inhibitors of the enzyme for the conversion of angiotensin.
FR7816377A 1978-05-22 1978-06-01 DERIVATIVES OF THIAZOLIDINECARBOXYLIC ACIDS AND RELATED ACIDS, USEFUL AS ANTI-HYPERTENSION AGENTS Granted FR2426685A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/907,452 US4192878A (en) 1976-12-03 1978-05-22 Derivatives of thiazolidinecarboxylic acids and related acids

Publications (2)

Publication Number Publication Date
FR2426685A2 true FR2426685A2 (en) 1979-12-21
FR2426685B2 FR2426685B2 (en) 1981-09-04

Family

ID=25424116

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7816377A Granted FR2426685A2 (en) 1978-05-22 1978-06-01 DERIVATIVES OF THIAZOLIDINECARBOXYLIC ACIDS AND RELATED ACIDS, USEFUL AS ANTI-HYPERTENSION AGENTS

Country Status (18)

Country Link
JP (1) JPS54151965A (en)
AU (1) AU521516B2 (en)
BE (1) BE867776R (en)
CA (1) CA1102812A (en)
CH (1) CH633782A5 (en)
DE (1) DE2823352A1 (en)
DK (1) DK242378A (en)
FR (1) FR2426685A2 (en)
HU (1) HU179780B (en)
IE (1) IE47075B1 (en)
IT (1) IT1156791B (en)
NZ (1) NZ187390A (en)
PH (1) PH14405A (en)
PL (1) PL207332A3 (en)
SE (1) SE7806468L (en)
SU (2) SU730303A3 (en)
YU (1) YU131478A (en)
ZA (1) ZA783013B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2445324A1 (en) * 1978-12-30 1980-07-25 Santen Pharmaceutical Co Ltd NOVEL DISULFIDE DERIVATIVES CONTAINING A PYRROLIDINE OR THIAZOLIDINE CYCLE USEFUL AS ANTIHYPERTENSORS AND FOR PREVENTING AND TREATING DIABETES COMPLICATIONS AND METHODS FOR THEIR PREPARATION

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692458A (en) * 1980-03-05 1987-09-08 University Of Miami Anti-hypertensive agents
RU2526619C2 (en) * 2012-12-12 2014-08-27 Федеральное государственное бюджетное учреждение науки Институт высокомолекулярных соединений Российской академии наук Method of obtaining (2r,4r)-2-alkyl-3-(2-mercaptobenzoyl)-1,3-thiazolidine-4-carboxylic acids

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2404635A1 (en) * 1977-09-28 1979-04-27 Science Union & Cie NEW THIOPROPRIONYLAMIDES, THEIR OBTAINING PROCEDURES AND THEIR USE IN THERAPEUTICS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2404635A1 (en) * 1977-09-28 1979-04-27 Science Union & Cie NEW THIOPROPRIONYLAMIDES, THEIR OBTAINING PROCEDURES AND THEIR USE IN THERAPEUTICS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2445324A1 (en) * 1978-12-30 1980-07-25 Santen Pharmaceutical Co Ltd NOVEL DISULFIDE DERIVATIVES CONTAINING A PYRROLIDINE OR THIAZOLIDINE CYCLE USEFUL AS ANTIHYPERTENSORS AND FOR PREVENTING AND TREATING DIABETES COMPLICATIONS AND METHODS FOR THEIR PREPARATION

Also Published As

Publication number Publication date
BE867776R (en) 1978-12-04
YU131478A (en) 1984-06-30
IT1156791B (en) 1987-02-04
IT7849660A0 (en) 1978-06-01
PL207332A3 (en) 1980-01-28
IE47075B1 (en) 1983-12-14
AU521516B2 (en) 1982-04-08
HU179780B (en) 1982-12-28
JPS54151965A (en) 1979-11-29
CH633782A5 (en) 1982-12-31
ZA783013B (en) 1979-06-27
IE781098L (en) 1979-11-22
AU3660278A (en) 1979-12-06
SE7806468L (en) 1979-11-23
FR2426685B2 (en) 1981-09-04
NZ187390A (en) 1980-05-27
PH14405A (en) 1981-06-25
DK242378A (en) 1979-11-23
SU816400A3 (en) 1981-03-23
CA1102812A (en) 1981-06-09
SU730303A3 (en) 1980-04-25
DE2823352A1 (en) 1979-11-29

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