FR2308374A1 - Derives n-(a-hydroxy-o-aminoalcanoyl)-1 de la desoxy-3' kanamycine a et procede pour leur preparation - Google Patents

Derives n-(a-hydroxy-o-aminoalcanoyl)-1 de la desoxy-3' kanamycine a et procede pour leur preparation

Info

Publication number
FR2308374A1
FR2308374A1 FR7612834A FR7612834A FR2308374A1 FR 2308374 A1 FR2308374 A1 FR 2308374A1 FR 7612834 A FR7612834 A FR 7612834A FR 7612834 A FR7612834 A FR 7612834A FR 2308374 A1 FR2308374 A1 FR 2308374A1
Authority
FR
France
Prior art keywords
aminoalcanoyl
desoxy
kanamycin
hydroxy
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7612834A
Other languages
English (en)
Other versions
FR2308374B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of FR2308374A1 publication Critical patent/FR2308374A1/fr
Application granted granted Critical
Publication of FR2308374B1 publication Critical patent/FR2308374B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FR7612834A 1975-04-24 1976-04-22 Derives n-(a-hydroxy-o-aminoalcanoyl)-1 de la desoxy-3' kanamycine a et procede pour leur preparation Granted FR2308374A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50049105A JPS51127045A (en) 1975-04-24 1975-04-24 A process for preparing 3'- deoxykanamycin a derivatives.

Publications (2)

Publication Number Publication Date
FR2308374A1 true FR2308374A1 (fr) 1976-11-19
FR2308374B1 FR2308374B1 (fr) 1978-11-17

Family

ID=12821793

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7612834A Granted FR2308374A1 (fr) 1975-04-24 1976-04-22 Derives n-(a-hydroxy-o-aminoalcanoyl)-1 de la desoxy-3' kanamycine a et procede pour leur preparation

Country Status (6)

Country Link
US (1) US4104372A (fr)
JP (1) JPS51127045A (fr)
CA (1) CA1058170A (fr)
DE (1) DE2618009C3 (fr)
FR (1) FR2308374A1 (fr)
GB (1) GB1538278A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0139553A2 (fr) * 1983-08-15 1985-05-02 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 1N-(omega-amino-alpha-hydroxyalkanoyl)-2',3'-didéoxykanamycine A et la préparation de ce produit
EP0317970A2 (fr) * 1987-11-27 1989-05-31 GIST BROCADES ITALY S.p.A. Procédé pour la synthèse de l'amikacine

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4283528A (en) * 1976-06-17 1981-08-11 Schering Corporation 1-N-aminohydroxyacyl derivatives of gentamicin B
CA1105455A (fr) * 1977-09-19 1981-07-21 Junji Irisawa Derives des aminoglycosides
JPS55105699A (en) * 1979-02-05 1980-08-13 Microbial Chem Res Found 3',4'-dideoxykanamycin a and its 1-n-aminoalkanoyl derivative
DE2921973A1 (de) * 1979-05-30 1980-12-11 Bayer Ag Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4410516A (en) * 1981-07-21 1983-10-18 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 1-N(αHydroxy-ω-aminoalkanoyl) derivatives of 5,3',4'-trideoxy- or 5,3', 4'-trideoxy-6'-N- methyl- or 5, 3', 4',6"-tetradeoxykannamyci B and production thereof
US4661474A (en) * 1984-12-15 1987-04-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 2',3'-dideoxy-2'-fluorokanamycin A and 1-N-(α-hydroxy-ω-aminoalkanoyl) derivatives thereof
JPS6253997A (ja) * 1985-09-03 1987-03-09 Kowa Co 新規なアミノ配糖体及びこれを含有する製剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929761A (en) * 1971-11-30 1975-12-30 Microbial Chem Res Found 3-Deoxykanamycin
US3904597A (en) * 1973-02-23 1975-09-09 Bristol Myers Co Antibiotic derivatives
GB1441202A (en) * 1973-05-15 1976-06-30 Microbial Chem Res Found 1-n-isoserylkanamycins and the production thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0139553A2 (fr) * 1983-08-15 1985-05-02 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 1N-(omega-amino-alpha-hydroxyalkanoyl)-2',3'-didéoxykanamycine A et la préparation de ce produit
EP0139553A3 (fr) * 1983-08-15 1986-08-13 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai 1N-(omega-amino-alpha-hydroxyalkanoyl)-2',3'-didéoxykanamycine A et la préparation de ce produit
EP0317970A2 (fr) * 1987-11-27 1989-05-31 GIST BROCADES ITALY S.p.A. Procédé pour la synthèse de l'amikacine
EP0317970A3 (fr) * 1987-11-27 1991-08-28 GIST BROCADES ITALY S.p.A. Procédé pour la synthèse de l'amikacine

Also Published As

Publication number Publication date
US4104372A (en) 1978-08-01
DE2618009B2 (de) 1978-04-27
CA1058170A (fr) 1979-07-10
DE2618009C3 (de) 1979-01-18
JPS5752358B2 (fr) 1982-11-06
GB1538278A (en) 1979-01-17
FR2308374B1 (fr) 1978-11-17
JPS51127045A (en) 1976-11-05
DE2618009A1 (de) 1976-11-04

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Legal Events

Date Code Title Description
ST Notification of lapse