FR2302087A1 - Compsns. contg. 2-(4-isobutylphenyl) butyric acid - useful as nonulcerogenic analgesic, antiinflammatory and antipyretic - Google Patents

Compsns. contg. 2-(4-isobutylphenyl) butyric acid - useful as nonulcerogenic analgesic, antiinflammatory and antipyretic

Info

Publication number
FR2302087A1
FR2302087A1 FR7506438A FR7506438A FR2302087A1 FR 2302087 A1 FR2302087 A1 FR 2302087A1 FR 7506438 A FR7506438 A FR 7506438A FR 7506438 A FR7506438 A FR 7506438A FR 2302087 A1 FR2302087 A1 FR 2302087A1
Authority
FR
France
Prior art keywords
compsns
isobutylphenyl
analgesic
butyric acid
antipyretic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7506438A
Other languages
French (fr)
Other versions
FR2302087B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JUSTE SA
Juste Quimico Farmaceutica SA
Original Assignee
JUSTE SA
Juste Quimico Farmaceutica SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JUSTE SA, Juste Quimico Farmaceutica SA filed Critical JUSTE SA
Priority to FR7506438A priority Critical patent/FR2302087A1/en
Publication of FR2302087A1 publication Critical patent/FR2302087A1/en
Application granted granted Critical
Publication of FR2302087B1 publication Critical patent/FR2302087B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The medical use of 2-(4-isobutylphenyl)butyric acid of formula (I) and its non-toxic organic or inorganic salts is new. Pref. compsns. contain 100-600 mg (I) or its salt plus vehicles or excipients appropriate for oral, rectal or parenteral administration. (I) has analgesic, anti-inflammatory and antipyretic activities. It does not irritate the gastric mucosa, evan after prolonged administration and has a very low toxicity (no figures). A typical capsule contains 200 mg (I) Na salt; 35 mg talc and 5 mg Mg stearate.
FR7506438A 1975-02-28 1975-02-28 Compsns. contg. 2-(4-isobutylphenyl) butyric acid - useful as nonulcerogenic analgesic, antiinflammatory and antipyretic Granted FR2302087A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7506438A FR2302087A1 (en) 1975-02-28 1975-02-28 Compsns. contg. 2-(4-isobutylphenyl) butyric acid - useful as nonulcerogenic analgesic, antiinflammatory and antipyretic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7506438A FR2302087A1 (en) 1975-02-28 1975-02-28 Compsns. contg. 2-(4-isobutylphenyl) butyric acid - useful as nonulcerogenic analgesic, antiinflammatory and antipyretic

Publications (2)

Publication Number Publication Date
FR2302087A1 true FR2302087A1 (en) 1976-09-24
FR2302087B1 FR2302087B1 (en) 1978-08-04

Family

ID=9151950

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7506438A Granted FR2302087A1 (en) 1975-02-28 1975-02-28 Compsns. contg. 2-(4-isobutylphenyl) butyric acid - useful as nonulcerogenic analgesic, antiinflammatory and antipyretic

Country Status (1)

Country Link
FR (1) FR2302087A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994017787A1 (en) * 1993-02-10 1994-08-18 Merck Patent Gmbh Capsule filled with a mixture of active ingredient in powder form and highly dispersed silicon dioxide

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS 1970, VOLUME 73 NO. 64 576G CITE LABO-PHARMA-PROBL.TECH. 1970, 18 186 PAGES 52-53 BOUCARD E.A. ) *
NATURE 1963 *
UNLISTED DRUGS 1965, PAGE 81-B-EXTRAIT CITANT LANCET 2:349 14 AOUT 1965 *
VOLUME 200, PAGES 271-272 ADAMS *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994017787A1 (en) * 1993-02-10 1994-08-18 Merck Patent Gmbh Capsule filled with a mixture of active ingredient in powder form and highly dispersed silicon dioxide

Also Published As

Publication number Publication date
FR2302087B1 (en) 1978-08-04

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Legal Events

Date Code Title Description
ST Notification of lapse