FR2301255A1 - Analgesic, anticholinergic sulphonyl-piperazines - prepd by reacting piperazine with sulphonyl-chlorides in two-stage reaction - Google Patents

Analgesic, anticholinergic sulphonyl-piperazines - prepd by reacting piperazine with sulphonyl-chlorides in two-stage reaction

Info

Publication number
FR2301255A1
FR2301255A1 FR7530225A FR7530225A FR2301255A1 FR 2301255 A1 FR2301255 A1 FR 2301255A1 FR 7530225 A FR7530225 A FR 7530225A FR 7530225 A FR7530225 A FR 7530225A FR 2301255 A1 FR2301255 A1 FR 2301255A1
Authority
FR
France
Prior art keywords
sulphonyl
act
analgesic
anticholinergic
piperazines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7530225A
Other languages
French (fr)
Other versions
FR2301255B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Liade SA
Original Assignee
Laboratorios Liade SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Liade SA filed Critical Laboratorios Liade SA
Publication of FR2301255A1 publication Critical patent/FR2301255A1/en
Application granted granted Critical
Publication of FR2301255B1 publication Critical patent/FR2301255B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Novel sulphonylpiperazines of formula (I): and X = Me, Cl, NH2 or NO2. have analgesic, bronchodilatory, local anaesthetic and anticholinergic act. The analgesic act may be of central origin. Pharmacological act. is present in the cardiovascular system which manifests itself in some of (I) as vasodilatory act. showing negative chronotropic as well as inotropic activity. These products appear to have heart-stimulating act of non-adrenergic origin. No significant modification of blood pressure is observed. (I) have wide therapeutic spectrum.
FR7530225A 1975-02-18 1975-10-02 Analgesic, anticholinergic sulphonyl-piperazines - prepd by reacting piperazine with sulphonyl-chlorides in two-stage reaction Granted FR2301255A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES434834A ES434834A1 (en) 1975-02-18 1975-02-18 Procedure for obtaining sulfonil piperazines. (Machine-translation by Google Translate, not legally binding)

Publications (2)

Publication Number Publication Date
FR2301255A1 true FR2301255A1 (en) 1976-09-17
FR2301255B1 FR2301255B1 (en) 1980-06-06

Family

ID=8468653

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7530225A Granted FR2301255A1 (en) 1975-02-18 1975-10-02 Analgesic, anticholinergic sulphonyl-piperazines - prepd by reacting piperazine with sulphonyl-chlorides in two-stage reaction

Country Status (5)

Country Link
JP (1) JPS51108078A (en)
CH (1) CH605876A5 (en)
DE (1) DE2545330A1 (en)
ES (1) ES434834A1 (en)
FR (1) FR2301255A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2553414A1 (en) * 1983-10-18 1985-04-19 Choay Sa NOVEL N-CYCLIC BENZENESULFONAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ACTIVE SUBSTANCES OF PHARMACEUTICAL COMPOSITIONS
US4871843A (en) * 1983-10-18 1989-10-03 Dropic-Societe Civile De Gestion De Droits De Propriete Industrielle Cyclic benzenesulfonamides, process for their preparation and their use as active substance of pharmaceutical compositions

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2553414A1 (en) * 1983-10-18 1985-04-19 Choay Sa NOVEL N-CYCLIC BENZENESULFONAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ACTIVE SUBSTANCES OF PHARMACEUTICAL COMPOSITIONS
US4760062A (en) * 1983-10-18 1988-07-26 Dropic, Societe Civile De Gestion De Droits De Propriete Industrielle Pharmaceutical compositions of N-heterocyclic benzenesulfonamides and their use
US4871843A (en) * 1983-10-18 1989-10-03 Dropic-Societe Civile De Gestion De Droits De Propriete Industrielle Cyclic benzenesulfonamides, process for their preparation and their use as active substance of pharmaceutical compositions

Also Published As

Publication number Publication date
CH605876A5 (en) 1978-10-13
DE2545330A1 (en) 1976-08-26
FR2301255B1 (en) 1980-06-06
ES434834A1 (en) 1976-12-01
JPS51108078A (en) 1976-09-25

Similar Documents

Publication Publication Date Title
GB1502472A (en) Bis(aminobenzoate)
GB1435139A (en) Thiazole derivatives
DE3470309D1 (en) N-chlorocarbonyloxy-5-norbornene-2,3-dicarboximide, process for its preparation and its use
ES433642A1 (en) Process for the production of nitro derivatives of aromatic compounds
ES438451A1 (en) Aminotetralols
IE36716L (en) Cyclic ureas
FR2301255A1 (en) Analgesic, anticholinergic sulphonyl-piperazines - prepd by reacting piperazine with sulphonyl-chlorides in two-stage reaction
JPS5227743A (en) Production of high-purity terephthalic acid
ES438780A1 (en) Process for the production of 7-d-a-amino-phenyl-acetamido-3- desacetoxy-cephalosporanic acid
GB1290174A (en)
MY102732A (en) A process for the manufacture of n, n-(dibenzohexatrienylene) ureas
JPS5257128A (en) Process for p-phenylenediamine
SE7613630L (en) PROCEDURE OF SYNTHESIS OF N-METHYL UCBAMIDES
GB1374365A (en) Nitrosourea derivatives
JPS51115402A (en) Process for preparation of alpha-amino acid
JPS5229491A (en) Process for conversion of nitrogen monoxide to nitrogen
ES408183A1 (en) Process of making penicillamine
ES430861A1 (en) Amoxidation procedure. (Machine-translation by Google Translate, not legally binding)
ES247384A1 (en) Process of production of an N- (5-nitro-2-furil) hydracide alkyliden of formula o2no-ch = N-a i " (Machine-translation by Google Translate, not legally binding)
GB1305860A (en)
GB1346706A (en) Substituted cysteines and the production thereof
ES8307006A1 (en) New apovincaminol derivatives
ES409908A1 (en) Linear polyamides and process for obtaining same batteries
GB1047257A (en)
ES271860A1 (en) Improvements relating to the manufacture of caprolactam

Legal Events

Date Code Title Description
ST Notification of lapse