FR2300131A1 - Alkaloid prodn by culturing Vinca minor cells - in undifferentiated state in liq medium (BE030876) - Google Patents

Alkaloid prodn by culturing Vinca minor cells - in undifferentiated state in liq medium (BE030876)

Info

Publication number
FR2300131A1
FR2300131A1 FR7503347A FR7503347A FR2300131A1 FR 2300131 A1 FR2300131 A1 FR 2300131A1 FR 7503347 A FR7503347 A FR 7503347A FR 7503347 A FR7503347 A FR 7503347A FR 2300131 A1 FR2300131 A1 FR 2300131A1
Authority
FR
France
Prior art keywords
alkaloid
culturing
undifferentiated state
prodn
vinca minor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7503347A
Other languages
French (fr)
Other versions
FR2300131B1 (en
Inventor
Vincent Petiard
Paul-Roger Guinebault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7503347A priority Critical patent/FR2300131A1/en
Priority to DE19762603588 priority patent/DE2603588A1/en
Priority to BE164063A priority patent/BE838232A/en
Priority to JP51011813A priority patent/JPS51104094A/en
Publication of FR2300131A1 publication Critical patent/FR2300131A1/en
Application granted granted Critical
Publication of FR2300131B1 publication Critical patent/FR2300131B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Abstract

Alkaloids are produced by culturing isolated cells (or small groups thereof) of Vinca minor in a morphogentically undifferentiated state in a liq. medium in vitro. The alkaloid mixts. obtained (including vincamine derivs.) can be used for therapeutic purposes. The process gives higher yields than extraction of the plant itself.
FR7503347A 1975-02-04 1975-02-04 Alkaloid prodn by culturing Vinca minor cells - in undifferentiated state in liq medium (BE030876) Granted FR2300131A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR7503347A FR2300131A1 (en) 1975-02-04 1975-02-04 Alkaloid prodn by culturing Vinca minor cells - in undifferentiated state in liq medium (BE030876)
DE19762603588 DE2603588A1 (en) 1975-02-04 1976-01-30 PROCESS FOR PRODUCING ALKALOIDS BY IN VITRO CELLS FROM VINCA MINOR L.
BE164063A BE838232A (en) 1975-02-04 1976-02-03 PRODUCTION OF ALKALOIDS AND PRODUCTS OBTAINED
JP51011813A JPS51104094A (en) 1975-02-04 1976-02-04 ARUKAROIDORUINOSEIZOHO

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7503347A FR2300131A1 (en) 1975-02-04 1975-02-04 Alkaloid prodn by culturing Vinca minor cells - in undifferentiated state in liq medium (BE030876)

Publications (2)

Publication Number Publication Date
FR2300131A1 true FR2300131A1 (en) 1976-09-03
FR2300131B1 FR2300131B1 (en) 1977-07-22

Family

ID=9150685

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7503347A Granted FR2300131A1 (en) 1975-02-04 1975-02-04 Alkaloid prodn by culturing Vinca minor cells - in undifferentiated state in liq medium (BE030876)

Country Status (4)

Country Link
JP (1) JPS51104094A (en)
BE (1) BE838232A (en)
DE (1) DE2603588A1 (en)
FR (1) FR2300131A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001010A1 (en) * 1980-09-12 1982-04-01 Bartlett D Plant-derived cell aggregate,plant granulate,production and use thereof
EP0050562A1 (en) * 1980-10-22 1982-04-28 Synthelabo Process for the production or biotransformation of metabolites by plant cells in vitro
WO1988000968A2 (en) * 1986-08-04 1988-02-11 Mitsui Petrochemical Industries, Ltd. Process for inducing secondary metabolite production in plant cultures and means thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5322324U (en) * 1976-08-05 1978-02-24
US4241536A (en) * 1976-11-10 1980-12-30 Saint Firmin Annette R Embryogenesis in vitro, induction of qualitative and quantitative changes in metabolites produced by plants and products thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH62A (en) * 1889-01-08 Armand Mieg Innovations to gun barrels
CH71A (en) * 1888-11-15 1889-06-13 Th Hunziker Apparatus for embroidering elongated needles for hand embroidery machines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH62A (en) * 1889-01-08 Armand Mieg Innovations to gun barrels
CH71A (en) * 1888-11-15 1889-06-13 Th Hunziker Apparatus for embroidering elongated needles for hand embroidery machines

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
1965 13.515 C CITE "LLOYDIA" 27 4 , 322-7) *
1965 13.526 E, CITE "LLOYDIA" 27 4 , 328-33 1964 *
1969 109.790 S CITE "LLOYDIA" 1969, 32 2 131-40 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982001010A1 (en) * 1980-09-12 1982-04-01 Bartlett D Plant-derived cell aggregate,plant granulate,production and use thereof
EP0050562A1 (en) * 1980-10-22 1982-04-28 Synthelabo Process for the production or biotransformation of metabolites by plant cells in vitro
WO1988000968A2 (en) * 1986-08-04 1988-02-11 Mitsui Petrochemical Industries, Ltd. Process for inducing secondary metabolite production in plant cultures and means thereof
WO1988000968A3 (en) * 1986-08-04 1988-03-24 Mitsui Petrochemical Ind Process for inducing secondary metabolite production in plant cultures and means thereof

Also Published As

Publication number Publication date
FR2300131B1 (en) 1977-07-22
BE838232A (en) 1976-08-03
JPS51104094A (en) 1976-09-14
DE2603588A1 (en) 1976-08-05

Similar Documents

Publication Publication Date Title
AU512590B2 (en) Cell culture method
AU641488B2 (en) Human hematopoietic stem cell
IL49154A (en) Method of increasing the yield in cultivation of tuber-producing plants
CA998428A (en) Cemented bipolar carbon electrode for batteries of high energy density
AU501563B2 (en) Making use ofthe energy carried bya fluid and supplied thereto by solar energy
ES426543A1 (en) Mycophenolic acid derivatives
FR2300131A1 (en) Alkaloid prodn by culturing Vinca minor cells - in undifferentiated state in liq medium (BE030876)
JPS5210292A (en) Production of functional adenine derivative and use of same for producing high molecular derivative
JPS51148085A (en) Fermentated medium and production of yeast for feeding animal by same
SE8000366L (en) NEW CEPHALOSPORIN DERIVATIVES, PREPARATION AND USE THEREOF
AU8153075A (en) Process forthe manufacture of pencils
JPS5251400A (en) Preparation of 6,13-dihydroquinacridones
JPS5216393A (en) Bonds for eel culture feed and process for producing bond components
JPS51123074A (en) Production process of fet
JPS5247978A (en) Method of converting methnol to protein rich mycelium by microorganism
GB1286222A (en) Coenzyme b12
AU448295B2 (en) Method forthe production of high energy fuels
ES493272A0 (en) ERGOTAMINE AND ALCALOID PREPARATION PROCEDURE OF THE ERGOTOXIN GROUP
IL35257A (en) Microbiological process for preparing 10-hydroxylated pentacyclic alkaloids of the yohimbane family
JPS51134056A (en) High-speed direct-connected differential amplifier
CA991572A (en) Fermentation process for the preparation of ergot alkaloids
DK0401997T3 (en) Method for preparing metastatic inhibitory factor
JPS5216956A (en) Self-bias type amplifier
IE39605B1 (en) N-demethylation of indole alkaloids
CS188419B1 (en) Device for the continuous production of microbial biomass in the process using volatile substrates

Legal Events

Date Code Title Description
TP Transmission of property