FR2293193A1 - Acides 4-(e)- et 4-(z)-7-methyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl) -nona-2,4,6,8-tetraene-carboxyliques, leurs derives et leurs applications therapeutiques - Google Patents
Acides 4-(e)- et 4-(z)-7-methyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl) -nona-2,4,6,8-tetraene-carboxyliques, leurs derives et leurs applications therapeutiquesInfo
- Publication number
- FR2293193A1 FR2293193A1 FR7536850A FR7536850A FR2293193A1 FR 2293193 A1 FR2293193 A1 FR 2293193A1 FR 7536850 A FR7536850 A FR 7536850A FR 7536850 A FR7536850 A FR 7536850A FR 2293193 A1 FR2293193 A1 FR 2293193A1
- Authority
- FR
- France
- Prior art keywords
- carboxylics
- tetraene
- nona
- cyclohexene
- trimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/09—Geometrical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742456959 DE2456959A1 (de) | 1974-12-03 | 1974-12-03 | 4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2293193A1 true FR2293193A1 (fr) | 1976-07-02 |
FR2293193B1 FR2293193B1 (fr) | 1979-09-21 |
Family
ID=5932289
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7536850A Granted FR2293193A1 (fr) | 1974-12-03 | 1975-12-02 | Acides 4-(e)- et 4-(z)-7-methyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl) -nona-2,4,6,8-tetraene-carboxyliques, leurs derives et leurs applications therapeutiques |
Country Status (7)
Country | Link |
---|---|
BE (1) | BE835902A (fr) |
CH (1) | CH619211A5 (fr) |
DE (1) | DE2456959A1 (fr) |
FR (1) | FR2293193A1 (fr) |
GB (1) | GB1526410A (fr) |
SE (1) | SE413139B (fr) |
ZA (1) | ZA757545B (fr) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0009777A1 (fr) * | 1978-10-07 | 1980-04-16 | BASF Aktiengesellschaft | N-(carboxy)phényl amides de l'acide rétinoique et 7,8-déhydro-rétinoique, procédé de préparation et compositions pharmaceutiques les contenant |
EP0071598A1 (fr) * | 1981-02-17 | 1983-02-16 | Gail S Bazzano | Utilisation de retinoides et de leur derive pour accroitre le taux de croissance des cheveux humains et pour accroitre le taux de croissance de la fourrure chez certains animaux a fourrure. |
EP0093770A1 (fr) * | 1981-11-09 | 1983-11-16 | Gail S Bazzano | Utilisation de retinoides et minoxydile(2,4-diamino-6-piperidino-pyrimidine-3-oxyde)pour ameliorer le taux de croissance des cheveux et traiter certains types d'alopecies chez l'homme. |
WO1995004036A1 (fr) * | 1993-01-11 | 1995-02-09 | Ligand Pharmaceuticals Inc. | Composes a activite selective pour les recepteurs du retinoide x, et systeme de modulation des processus utilisant des recepteurs du retinoide x comme mediateurs |
EP0734371A1 (fr) * | 1993-12-15 | 1996-10-02 | Avon Products, Inc. | Nouveaux composes conjugues de retinoides et procedes de traitement du vieillissement de la peau |
WO2007019503A2 (fr) * | 2005-08-08 | 2007-02-15 | President And Fellows Of Harvard College | Gestion de troubles ophtalmologiques tels que la degenerescence maculaire |
US7655699B1 (en) | 1992-04-22 | 2010-02-02 | Eisai Inc. | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH651007A5 (de) * | 1982-06-24 | 1985-08-30 | Hoffmann La Roche | Polyenverbindungen. |
US4539154A (en) * | 1983-06-15 | 1985-09-03 | Hoffmann-La Roche Inc. | Polyene compounds |
US4743400A (en) * | 1986-09-22 | 1988-05-10 | Mcneilab, Inc. | Process for preparing retinoyl chlorides |
US5962731A (en) * | 1992-04-22 | 1999-10-05 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
US5780676A (en) * | 1992-04-22 | 1998-07-14 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors |
EP1610772A4 (fr) | 2003-03-14 | 2008-06-18 | Univ Washington | Substituts de retinoides et agonistes d'ospine et methodes d'utilisation correspondantes |
DK2397133T3 (en) | 2004-06-18 | 2017-10-30 | Univ Washington | RETINAL DERIVATIVES AND METHODS OF USING ITS FOR TREATMENT OF VISION DISORDERS |
WO2009102418A1 (fr) | 2008-02-11 | 2009-08-20 | University Of Washington | Procédés pour le traitement et la prévention d'un dysfonctionnement rétinien lié à l'âge |
CN102612375B (zh) | 2009-09-15 | 2016-01-27 | Qlt股份有限公司 | 含有在脂质媒介物中的9-顺式-视黄酯的药物制剂 |
AU2011244024B2 (en) | 2010-04-19 | 2015-12-10 | Eluminex Biosciences (Suzhou) Limited | Therapeutic regimen and method for treating or ameliorating visual disorders associated with an endogenous retinoid deficiency |
JP6576636B2 (ja) | 2012-03-01 | 2019-09-18 | ノベリオン セラピューティクス インコーポレイテッド | 内因性レチノイド欠乏に関連する視覚障害における視覚機能を改善するための治療的計画および方法 |
-
1974
- 1974-12-03 DE DE19742456959 patent/DE2456959A1/de not_active Withdrawn
-
1975
- 1975-11-20 SE SE7513080A patent/SE413139B/sv unknown
- 1975-11-25 BE BE162142A patent/BE835902A/fr not_active IP Right Cessation
- 1975-12-01 CH CH1559775A patent/CH619211A5/de not_active IP Right Cessation
- 1975-12-02 ZA ZA00757545A patent/ZA757545B/xx unknown
- 1975-12-02 FR FR7536850A patent/FR2293193A1/fr active Granted
- 1975-12-02 GB GB49370/75A patent/GB1526410A/en not_active Expired
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0009777A1 (fr) * | 1978-10-07 | 1980-04-16 | BASF Aktiengesellschaft | N-(carboxy)phényl amides de l'acide rétinoique et 7,8-déhydro-rétinoique, procédé de préparation et compositions pharmaceutiques les contenant |
EP0071598A1 (fr) * | 1981-02-17 | 1983-02-16 | Gail S Bazzano | Utilisation de retinoides et de leur derive pour accroitre le taux de croissance des cheveux humains et pour accroitre le taux de croissance de la fourrure chez certains animaux a fourrure. |
EP0071598A4 (fr) * | 1981-02-17 | 1983-06-08 | Gail S Bazzano | Utilisation de retinoides et de leur derive pour accroitre le taux de croissance des cheveux humains et pour accroitre le taux de croissance de la fourrure chez certains animaux a fourrure. |
EP0093770A1 (fr) * | 1981-11-09 | 1983-11-16 | Gail S Bazzano | Utilisation de retinoides et minoxydile(2,4-diamino-6-piperidino-pyrimidine-3-oxyde)pour ameliorer le taux de croissance des cheveux et traiter certains types d'alopecies chez l'homme. |
EP0093770A4 (fr) * | 1981-11-09 | 1987-11-25 | Gail S Bazzano | Utilisation de retinoides et minoxydile(2,4-diamino-6-piperidino-pyrimidine-3-oxyde)pour ameliorer le taux de croissance des cheveux et traiter certains types d'alopecies chez l'homme. |
US7655699B1 (en) | 1992-04-22 | 2010-02-02 | Eisai Inc. | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
WO1995004036A1 (fr) * | 1993-01-11 | 1995-02-09 | Ligand Pharmaceuticals Inc. | Composes a activite selective pour les recepteurs du retinoide x, et systeme de modulation des processus utilisant des recepteurs du retinoide x comme mediateurs |
EP0734371A1 (fr) * | 1993-12-15 | 1996-10-02 | Avon Products, Inc. | Nouveaux composes conjugues de retinoides et procedes de traitement du vieillissement de la peau |
EP0734371A4 (fr) * | 1993-12-15 | 1997-03-05 | Avon Prod Inc | Nouveaux composes conjugues de retinoides et procedes de traitement du vieillissement de la peau |
US7566808B2 (en) | 2004-02-17 | 2009-07-28 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
WO2007019503A2 (fr) * | 2005-08-08 | 2007-02-15 | President And Fellows Of Harvard College | Gestion de troubles ophtalmologiques tels que la degenerescence maculaire |
WO2007019503A3 (fr) * | 2005-08-08 | 2007-04-26 | Harvard College | Gestion de troubles ophtalmologiques tels que la degenerescence maculaire |
Also Published As
Publication number | Publication date |
---|---|
DE2456959A1 (de) | 1976-06-16 |
GB1526410A (en) | 1978-09-27 |
SE7513080L (sv) | 1976-06-04 |
SE413139B (sv) | 1980-04-21 |
CH619211A5 (en) | 1980-09-15 |
ZA757545B (en) | 1976-12-29 |
BE835902A (fr) | 1976-05-25 |
FR2293193B1 (fr) | 1979-09-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |