FR2291764A1 - Diacylnucleosides et procede de preparation - Google Patents

Diacylnucleosides et procede de preparation

Info

Publication number
FR2291764A1
FR2291764A1 FR7535692A FR7535692A FR2291764A1 FR 2291764 A1 FR2291764 A1 FR 2291764A1 FR 7535692 A FR7535692 A FR 7535692A FR 7535692 A FR7535692 A FR 7535692A FR 2291764 A1 FR2291764 A1 FR 2291764A1
Authority
FR
France
Prior art keywords
diacylnucleosides
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7535692A
Other languages
English (en)
French (fr)
Other versions
FR2291764B1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Corp
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Asahi Kasei Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd, Asahi Kasei Kogyo KK filed Critical Asahi Chemical Industry Co Ltd
Publication of FR2291764A1 publication Critical patent/FR2291764A1/fr
Application granted granted Critical
Publication of FR2291764B1 publication Critical patent/FR2291764B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR7535692A 1974-11-22 1975-11-21 Diacylnucleosides et procede de preparation Granted FR2291764A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49133556A JPS5159880A (en) 1974-11-22 1974-11-22 N44 ashirunukureoshidojikarubonsanesuteruno seiho

Publications (2)

Publication Number Publication Date
FR2291764A1 true FR2291764A1 (fr) 1976-06-18
FR2291764B1 FR2291764B1 (enExample) 1978-11-10

Family

ID=15107559

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7535692A Granted FR2291764A1 (fr) 1974-11-22 1975-11-21 Diacylnucleosides et procede de preparation

Country Status (7)

Country Link
US (1) US4097665A (enExample)
JP (1) JPS5159880A (enExample)
CH (1) CH624414A5 (enExample)
DE (1) DE2552293A1 (enExample)
FR (1) FR2291764A1 (enExample)
GB (1) GB1533991A (enExample)
HU (1) HU181839B (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH640411A5 (de) * 1978-05-26 1984-01-13 Kureha Chemical Ind Co Ltd Medikament zur behandlung von hyperglykaemie, hyperlipaemie, hypertension, entzuendungen, schmerz, fieber oder tumoren.
US4340728A (en) * 1979-11-28 1982-07-20 Fuji Kagaku Kogyo Kabushiki Kaisha Nucleoside derivatives and process for preparing same
JPS56128741U (enExample) * 1980-02-28 1981-09-30
DE3100478A1 (de) * 1981-01-09 1982-08-12 Dr. Thilo & Co GmbH, 8021 Sauerlach 5'ester von pyrimidinnucleosiden mit antiviraler wirksamkeit, verfahren zur herstellung und daraus hergestellte arzneimittel
JPS57135145U (enExample) * 1981-02-18 1982-08-23
DE3481191D1 (de) * 1983-07-20 1990-03-08 Teijin Ltd Antineoplastisches mittel.
WO1986006726A1 (en) * 1985-05-15 1986-11-20 Integrated Genetics, Inc. Cytidine analogs
US6329350B1 (en) * 1987-10-28 2001-12-11 Pro-Neuron, Inc. Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis
GB9307043D0 (en) * 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
US5952294A (en) * 1996-07-31 1999-09-14 University Of Pittsburgh Of The Commonwealth System Of Higher Education Peptidyl prodrugs and methods of making and using the same
CN101296934A (zh) * 2005-08-29 2008-10-29 谢麦吉斯有限公司 吉西他滨以及相关中间体的制备方法
WO2007092705A2 (en) * 2006-02-07 2007-08-16 Chemagis Ltd. Process for preparing gemcitabine and associated intermediates
US20070249823A1 (en) * 2006-04-20 2007-10-25 Chemagis Ltd. Process for preparing gemcitabine and associated intermediates
US20080262215A1 (en) * 2007-04-23 2008-10-23 Chemagis Ltd. Gemcitabine production process

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3317512A (en) * 1965-06-01 1967-05-02 Upjohn Co 5', 5'-dinucleoside phosphates
US3300478A (en) * 1965-06-01 1967-01-24 Upjohn Co Arabinofuranosyl 2', 5'-and 3'-5'-dinucleoside phosphates and process therefor
US3457253A (en) * 1965-06-01 1969-07-22 Upjohn Co 5',5'-di-(ara)-nucleoside phosphates
US3309359A (en) * 1965-10-22 1967-03-14 Hoffmann La Roche N-mono-acyl-5-fluorocytosine derivatives and process
US3847898A (en) * 1969-05-27 1974-11-12 Upjohn Co N4-trihaloethoxy carbonyl arabino-furanosyl cytosine 5'-esters
US3709874A (en) * 1970-03-19 1973-01-09 Syntex Corp 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing
US3920630A (en) * 1970-09-24 1975-11-18 Upjohn Co 2,2{40 -Anhydro-ara-cytidine compounds and process of preparation
US3894000A (en) * 1971-01-27 1975-07-08 Upjohn Co Ara-cytidine derivatives and process of preparation
US3998807A (en) * 1972-03-03 1976-12-21 Syntex (U.S.A.) Inc. Arabinofuranosyl cytosines and methods of making
US3864483A (en) * 1972-03-22 1975-02-04 Abbott Lab Adenosine-5{40 -carboxylic acid amides

Also Published As

Publication number Publication date
FR2291764B1 (enExample) 1978-11-10
DE2552293A1 (de) 1976-08-12
HU181839B (en) 1983-11-28
US4097665A (en) 1978-06-27
JPS5159880A (en) 1976-05-25
JPS541315B2 (enExample) 1979-01-23
CH624414A5 (enExample) 1981-07-31
GB1533991A (en) 1978-11-29

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Legal Events

Date Code Title Description
ST Notification of lapse