FR2291763A1 - Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppression - Google Patents

Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppression

Info

Publication number
FR2291763A1
FR2291763A1 FR7535387A FR7535387A FR2291763A1 FR 2291763 A1 FR2291763 A1 FR 2291763A1 FR 7535387 A FR7535387 A FR 7535387A FR 7535387 A FR7535387 A FR 7535387A FR 2291763 A1 FR2291763 A1 FR 2291763A1
Authority
FR
France
Prior art keywords
antitumorous
phosphamide
preparation
new products
cyclic derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7535387A
Other languages
English (en)
French (fr)
Inventor
Akira Takamizawa
Tsuyoshi Iwata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of FR2291763A1 publication Critical patent/FR2291763A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/14—Esters of phosphoric acids containing P(=O)-halide groups
    • C07F9/1403—Esters of phosphoric acids containing P(=O)-halide groups containing the structure Hal-P(=O)-O-unsaturated acyclic group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2412—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of unsaturated acyclic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7535387A 1974-11-20 1975-11-19 Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppression Withdrawn FR2291763A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49133257A JPS5159886A (xx) 1974-11-20 1974-11-20

Publications (1)

Publication Number Publication Date
FR2291763A1 true FR2291763A1 (fr) 1976-06-18

Family

ID=15100374

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7535387A Withdrawn FR2291763A1 (fr) 1974-11-20 1975-11-19 Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppression

Country Status (9)

Country Link
JP (1) JPS5159886A (xx)
AU (1) AU500813B2 (xx)
CA (1) CA1051914A (xx)
CH (1) CH602777A5 (xx)
DE (1) DE2552135A1 (xx)
FR (1) FR2291763A1 (xx)
GB (1) GB1527497A (xx)
NL (1) NL7513590A (xx)
SE (1) SE7513007L (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3133309A1 (de) * 1980-09-10 1982-04-15 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld 4-carbamoyloxy-oxazaphosphorine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
WO2000071134A1 (en) * 1999-05-24 2000-11-30 Southern Research Institute Isophosphoramide mustard analogs and use thereof
NZ555323A (en) 2004-10-25 2010-12-24 Dekk Tec Inc Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents
US7964583B2 (en) 2006-02-17 2011-06-21 Ziopharm Oncology, Inc. Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents
ES2547302T3 (es) 2007-04-06 2015-10-05 Ziopharm Oncology, Inc. Sales de mostaza de isofosforamida y análogos de las mismas

Also Published As

Publication number Publication date
DE2552135A1 (de) 1976-05-26
JPS5159886A (xx) 1976-05-25
SE7513007L (sv) 1976-05-21
NL7513590A (nl) 1976-05-24
AU8681675A (en) 1977-05-26
CH602777A5 (xx) 1978-07-31
CA1051914A (en) 1979-04-03
AU500813B2 (en) 1979-05-10
GB1527497A (en) 1978-10-04

Similar Documents

Publication Publication Date Title
BE860971A (fr) Procede de preparation de n,n'-methylenebis-(0,0-diaryl n-phosphonomethylglycinonitriles, nouveaux produits ainsi obtenus et leur utilisation
RO69412A (ro) Procedeu pentru prepararea unor compozitii polimere pe baza de polipropilena
BE856860A (fr) Procede de preparation de derives d'androstan-17-one, produits obtenus et leur utilisation
FR2279720A1 (fr) Procede de preparation d'alkyltetracyclines et nouveaux produits obtenus
FR2274299A1 (fr) Procede de preparation de 7b-acylamino-7a-alcoxycephalosporines et 6b-acylamino-6a-alcoxy-penicillines, nouveaux produits obtenus et leur application
BE783260A (fr) Nouveaux derives d'imidazolidinone-(2), leur procede de preparation et leur application comme herbicides
BE854167A (fr) Procede de preparation de derives de n-phosphono-methylglycine, nouveaux produits ainsi obtenus et leur utilisation comme herbicides
BE828430A (fr) Phenylalcoylamines, leur procede d'obtention et leur application commemedicaments
BE829051A (fr) Nouveaux derives d'acide 3-amino-phenylacetique, leur procede de preparation et leur application comme herbicides
FR2317924A1 (fr) Procede de production de derives d'ortho-aminobutyrophenone, nouveaux produits ainsi obtenus et leur utilisation comme agents analgesiques et antipsychose
FR2291763A1 (fr) Procede de preparation de derives cycliques de phosphamide, nouveaux produits ainsi obtenus et leur utilisation comme agents antitumeurs et d'immunosuppression
OA04771A (fr) Nouveaux 2, 3-dihydrobenzofuranyl-7-N-méthylcarbamates N-sulfénylés, leur procédé de préparation et leur application comme insecticide.
OA05065A (fr) Nouveaux carbamates, leur procédé de préparation et leur application comme insecticides et acaricides.
FR2290207A1 (fr) Nouveaux derives de 3,4-dihydrocarbostyril et leur procede de preparation
BE844745A (fr) Procede de preparation de derives de 5-andro-sten-17-one, produits ainsi obtenus et leur utilisation
BE836925A (fr) Nouveaux derives de thiouree, leur procede de preparation et leur application comme fongicides
FR2286144A1 (fr) Nouveaux phosphorothiolates, leur procede de preparation et leur application comme pesticides
FR2293940A1 (fr) Procede de production de 9-aminoalkyl-methanoanthracenes, nouveaux produits ainsi obtenus et leur utilisation notamment comme tranquillisants
FR2308631A1 (fr) Nouveaux n-alcoyl et cycloalcoyl thioacrylamides, leur procede de preparation et leur application comme fongicides
FR2290206A1 (fr) Procede de preparation de 1,2,3,4-tetrahydroisoquinoleines, nouveaux produits ainsi obtenus et leur utilisation comme agents a activite de relaxation sur les muscles lisses
FR2282424A1 (fr) Nouveaux triazapentadienes, leur procede de preparation et leur application comme insecticides et acaricides
FR2316936A1 (fr) Procede de production de derives de morpholine, nouveaux produits ainsi obtenus et leur utilisation comme produits antidepressifs
FR2293936A1 (fr) Procede de preparation de composes tricycliques de dibenzazepine, nouveaux produits ainsi obtenus et leur utilisation comme produits antidepressifs
OA05031A (fr) Nouveaux arylcarbamates N-sulfénylés, leur procédé de préparation et leur application comme insecticides.
OA04801A (fr) Nouveaux N-méthyl-carbamates N-sulfénylés, leur procédé de préparation et leur application comme insecticides et acaricides.

Legal Events

Date Code Title Description
ST Notification of lapse