FR2289929A1 - Systeme d'eclairement pour detecter par fluorescence des particules de dimensions inferieures au micron - Google Patents

Systeme d'eclairement pour detecter par fluorescence des particules de dimensions inferieures au micron

Info

Publication number
FR2289929A1
FR2289929A1 FR7532467A FR7532467A FR2289929A1 FR 2289929 A1 FR2289929 A1 FR 2289929A1 FR 7532467 A FR7532467 A FR 7532467A FR 7532467 A FR7532467 A FR 7532467A FR 2289929 A1 FR2289929 A1 FR 2289929A1
Authority
FR
France
Prior art keywords
micron
particles
lighting system
fluorescent detection
sizes less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7532467A
Other languages
English (en)
French (fr)
Other versions
FR2289929B1 (US06650917-20031118-M00005.png
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Block Engineering Inc
Original Assignee
Block Engineering Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Block Engineering Inc filed Critical Block Engineering Inc
Publication of FR2289929A1 publication Critical patent/FR2289929A1/fr
Application granted granted Critical
Publication of FR2289929B1 publication Critical patent/FR2289929B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G02B21/08—Condensers
    • G02B21/082—Condensers for incident illumination only
    • G02B21/084—Condensers for incident illumination only having annular illumination around the objective

Landscapes

  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
FR7532467A 1974-10-24 1975-10-23 Systeme d'eclairement pour detecter par fluorescence des particules de dimensions inferieures au micron Granted FR2289929A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/517,504 US3999855A (en) 1974-10-24 1974-10-24 Illumination system

Publications (2)

Publication Number Publication Date
FR2289929A1 true FR2289929A1 (fr) 1976-05-28
FR2289929B1 FR2289929B1 (US06650917-20031118-M00005.png) 1979-07-06

Family

ID=24060082

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7532467A Granted FR2289929A1 (fr) 1974-10-24 1975-10-23 Systeme d'eclairement pour detecter par fluorescence des particules de dimensions inferieures au micron

Country Status (7)

Country Link
US (1) US3999855A (US06650917-20031118-M00005.png)
JP (1) JPS5165956A (US06650917-20031118-M00005.png)
AU (1) AU8581675A (US06650917-20031118-M00005.png)
DE (1) DE2546952A1 (US06650917-20031118-M00005.png)
FR (1) FR2289929A1 (US06650917-20031118-M00005.png)
GB (1) GB1492203A (US06650917-20031118-M00005.png)
NL (1) NL7512371A (US06650917-20031118-M00005.png)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2357888A1 (fr) * 1976-04-01 1978-02-03 Cerberus Ag Detecteur de fumee
JPS55500589A (US06650917-20031118-M00005.png) * 1978-08-30 1980-09-04
JPS58198762A (ja) * 1982-05-15 1983-11-18 Iseki & Co Ltd 粒状物の流下検出装置
JPS58185819U (ja) * 1982-06-02 1983-12-10 株式会社ニコン リングスリツト絞りを有する照明光源装置
FR2565689B1 (fr) * 1984-06-12 1987-11-20 Elf France Procede et dispositif pour la determination du point de trouble d'un gazole
US4893886A (en) * 1987-09-17 1990-01-16 American Telephone And Telegraph Company Non-destructive optical trap for biological particles and method of doing same
US4886357A (en) * 1988-09-06 1989-12-12 Harrick Nicolas J Internal reflection element with insensitive edges
US5486701A (en) * 1992-06-16 1996-01-23 Prometrix Corporation Method and apparatus for measuring reflectance in two wavelength bands to enable determination of thin film thickness
US5747813A (en) * 1992-06-16 1998-05-05 Kla-Tencop. Corporation Broadband microspectro-reflectometer
EP0627643B1 (en) * 1993-06-03 1999-05-06 Hamamatsu Photonics K.K. Laser scanning optical system using axicon
EP1562035B1 (en) * 1997-01-31 2017-01-25 Xy, Llc Optical apparatus and method
US5982534A (en) * 1997-06-18 1999-11-09 The Regents Of The University Of California Specimen illumination apparatus with optical cavity for dark field illumination
US6438396B1 (en) 1998-11-05 2002-08-20 Cytometrics, Inc. Method and apparatus for providing high contrast imaging
JP2000250100A (ja) 1999-03-01 2000-09-14 Mitsutoyo Corp 光学測定機用照明装置
US6185051B1 (en) * 1999-06-23 2001-02-06 Read-Rite Corporation High numerical aperture optical focusing device for use in data storage systems
JP3783826B2 (ja) * 2000-01-17 2006-06-07 横河電機株式会社 バイオチップ読み取り装置
DE10222785B4 (de) * 2002-05-23 2004-12-16 Wendlandt, Erhard Verfahren und Vorrichtung zur Probenuntersuchung
US7330255B2 (en) * 2004-12-09 2008-02-12 University Of Chicago Total internal reflection fluorescence apparatus
US7538874B2 (en) * 2006-03-23 2009-05-26 Hach Company Measurement of light from a predefined scatter angle from particulate matter in a media
US9291562B2 (en) 2011-11-15 2016-03-22 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Method and apparatus for tracking a particle, particularly a single molecule, in a sample
DE102011055367B4 (de) * 2011-11-15 2017-02-09 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren und Vorrichtung zum Verfolgen einer Bewegung eines Partikels, insbesondere eines einzelnen Moleküls, in einer Probe
US9500847B2 (en) 2012-10-12 2016-11-22 Spectral Applied Research Inc. Total internal reflectance fluorescence (TIRF) microscopy across multiple wavelengths simultaneously
US9690085B2 (en) * 2014-01-30 2017-06-27 Olympus Corporation Microscope illumination apparatus, microscope, and microscope illumination method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3506360A (en) * 1967-10-30 1970-04-14 Gamrad Inc Turbidity indicator using superimposed converging light beams
US3700330A (en) * 1971-10-13 1972-10-24 Gen Motors Corp Electro-optical vehicle exhaust particulate monitor
US3850525A (en) * 1973-07-09 1974-11-26 Beckman Instruments Inc Simultaneous multiple measurements in laser photometers

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number Publication date
JPS5165956A (US06650917-20031118-M00005.png) 1976-06-08
AU8581675A (en) 1977-04-21
DE2546952A1 (de) 1976-04-29
USB517504I5 (US06650917-20031118-M00005.png) 1976-03-09
FR2289929B1 (US06650917-20031118-M00005.png) 1979-07-06
US3999855A (en) 1976-12-28
GB1492203A (en) 1977-11-16
NL7512371A (nl) 1976-04-27

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Legal Events

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ST Notification of lapse