FR2288518A1 - Composes azotes araliphatiques et leur procede de preparation - Google Patents
Composes azotes araliphatiques et leur procede de preparationInfo
- Publication number
- FR2288518A1 FR2288518A1 FR7532135A FR7532135A FR2288518A1 FR 2288518 A1 FR2288518 A1 FR 2288518A1 FR 7532135 A FR7532135 A FR 7532135A FR 7532135 A FR7532135 A FR 7532135A FR 2288518 A1 FR2288518 A1 FR 2288518A1
- Authority
- FR
- France
- Prior art keywords
- araliphatic
- preparation process
- nitrogen compounds
- nitrogen
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742450989 DE2450989A1 (de) | 1974-10-26 | 1974-10-26 | Biphenylyl-alkylamine und verfahren zu ihrer herstellung |
DE19752523565 DE2523565A1 (de) | 1975-05-28 | 1975-05-28 | Araliphatische stickstoffverbindungen und verfahren zu ihrer herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2288518A1 true FR2288518A1 (fr) | 1976-05-21 |
FR2288518B1 FR2288518B1 (fr) | 1980-05-30 |
Family
ID=25767882
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7532135A Granted FR2288518A1 (fr) | 1974-10-26 | 1975-10-21 | Composes azotes araliphatiques et leur procede de preparation |
Country Status (16)
Country | Link |
---|---|
US (2) | US4110447A (fr) |
JP (1) | JPS51125231A (fr) |
AT (1) | AT347928B (fr) |
AU (1) | AU497803B2 (fr) |
CA (1) | CA1073907A (fr) |
DD (1) | DD122680A5 (fr) |
DK (1) | DK479575A (fr) |
ES (4) | ES442058A1 (fr) |
FR (1) | FR2288518A1 (fr) |
GB (1) | GB1476106A (fr) |
HU (1) | HU175263B (fr) |
IE (1) | IE43071B1 (fr) |
IL (1) | IL48319A0 (fr) |
LU (1) | LU73641A1 (fr) |
NL (1) | NL7512485A (fr) |
SE (1) | SE7511932L (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2398056A1 (fr) * | 1977-07-20 | 1979-02-16 | Merck Patent Gmbh | Thioethers basiques et leur procede de preparation |
EP0176049A2 (fr) * | 1984-09-28 | 1986-04-02 | Consiglio Nazionale Delle Ricerche | Dérivés de l'aminoalkylnaphtalène doués d'une activité pharmacologique |
EP0539805A1 (fr) * | 1991-10-31 | 1993-05-05 | ASTA Medica Aktiengesellschaft | Phthalazines substituées en position 1 par un groupe éther ou thioéther et procédé pour leur préparation |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL48319A0 (en) * | 1974-10-26 | 1975-12-31 | Merck Patent Gmbh | Araliphatic nitrogen compounds and a process for their preparation |
AT354187B (de) * | 1976-11-22 | 1979-12-27 | Hoffmann La Roche | Fungizides mittel |
GB2010813B (en) * | 1977-10-19 | 1982-07-28 | Wellcome Found | Imidazole derivatives and salts thereof their synthesis and intermediates and pharmaceutical formulations |
US4396771A (en) * | 1977-10-19 | 1983-08-02 | Burroughs Wellcome Co. | Imidazole derivatives and salts thereof |
CA1151164A (fr) * | 1978-01-13 | 1983-08-02 | Atsuyuki Kojima | Composes cetoniques conjugues; fabrication et utilisation |
IT1097314B (it) * | 1978-07-26 | 1985-08-31 | Recordati Chem Pharm | Derivati dell'imidazolo ad attivita' anticonvulsivante |
US4277471A (en) * | 1979-03-12 | 1981-07-07 | Eli Lilly And Company | 1,1-Biphenyl-2-yl alkylamines, formulations and antiarrhythmic treatment |
IL59557A (en) * | 1979-03-12 | 1983-10-31 | Lilly Co Eli | 1,1-biphenyl-2-yl propyl butyl and pentyl amines,their preparation and pharmaceutical compositions comprising them |
US4397855A (en) * | 1981-06-26 | 1983-08-09 | Warner-Lambert Company | 4-(Substituted)-α, α-dimethyl-1-piperazine pentanoic acids and derivatives as anti-arteriosclerotic agents and method |
IT1171605B (it) * | 1981-10-22 | 1987-06-10 | Roussel Maestretti Spa | Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione |
EP0365064B1 (fr) * | 1988-10-10 | 1992-10-21 | Akzo N.V. | Composés aromatiques substitués ayant une action sur le système nerveux |
US6297239B1 (en) | 1997-10-08 | 2001-10-02 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
EP2027087A2 (fr) | 2006-05-18 | 2009-02-25 | MannKind Corporation | Inhibiteurs de kinases intracellulaires |
EP2520561B1 (fr) | 2007-06-08 | 2016-02-10 | MannKind Corporation | Inhibiteurs IRE-1A |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2543271A (en) * | 1951-02-27 | Biphenyl compounds | ||
US2441518A (en) * | 1945-08-04 | 1948-05-11 | Sharp & Dohme Inc | Preparation of arylaliphatic amines |
US2680115A (en) * | 1949-01-28 | 1954-06-01 | Maurice L Tainter | Substituted tertiary-aminoalkyl carbinols |
US2723269A (en) * | 1949-11-03 | 1955-11-08 | American Cyanamid Co | Piperidino tertiary amino alcohols |
US2771469A (en) * | 1953-12-30 | 1956-11-20 | Merck & Co Inc | Quaternary ammonium salts of deltahydrocarbyoxyphenyl gamma-hydroxy amines |
US3058987A (en) * | 1959-09-21 | 1962-10-16 | Hoffmann La Roche | 3-amino-2-aminomethyl-1-phenyl-1-propanols |
FR1504889A (fr) * | 1966-07-14 | 1967-12-08 | Labofina Sa | Procédé de résolution des alpha-arylalkylamines en leurs antipodes optiques |
US3532712A (en) * | 1967-09-29 | 1970-10-06 | Aldrich Chem Co Inc | N'-cyclopropyl ethylenediamine derivatives |
IL48319A0 (en) * | 1974-10-26 | 1975-12-31 | Merck Patent Gmbh | Araliphatic nitrogen compounds and a process for their preparation |
US4055664A (en) * | 1975-02-10 | 1977-10-25 | Armour Pharmaceutical Company | Pharmaceutical preparations containing 4-(4-biphenylyl) butylamines and treatment of the animal organism therewith |
-
1975
- 1975-10-20 IL IL48319A patent/IL48319A0/xx unknown
- 1975-10-21 FR FR7532135A patent/FR2288518A1/fr active Granted
- 1975-10-22 US US05/624,762 patent/US4110447A/en not_active Expired - Lifetime
- 1975-10-22 AU AU85937/75A patent/AU497803B2/en not_active Expired
- 1975-10-23 GB GB4362875A patent/GB1476106A/en not_active Expired
- 1975-10-23 CA CA238,196A patent/CA1073907A/fr not_active Expired
- 1975-10-24 NL NL7512485A patent/NL7512485A/xx not_active Application Discontinuation
- 1975-10-24 AT AT813575A patent/AT347928B/de not_active IP Right Cessation
- 1975-10-24 DD DD189045A patent/DD122680A5/xx unknown
- 1975-10-24 DK DK479575A patent/DK479575A/da unknown
- 1975-10-24 SE SE7511932A patent/SE7511932L/xx unknown
- 1975-10-24 IE IE2321/75A patent/IE43071B1/en unknown
- 1975-10-24 LU LU73641A patent/LU73641A1/xx unknown
- 1975-10-24 HU HU75ME1913A patent/HU175263B/hu unknown
- 1975-10-24 ES ES442058A patent/ES442058A1/es not_active Expired
- 1975-10-27 JP JP50129776A patent/JPS51125231A/ja active Pending
-
1977
- 1977-02-28 ES ES456349A patent/ES456349A1/es not_active Expired
- 1977-02-28 ES ES456348A patent/ES456348A1/es not_active Expired
- 1977-02-28 ES ES456347A patent/ES456347A1/es not_active Expired
-
1978
- 1978-04-11 US US05/895,417 patent/US4239759A/en not_active Expired - Lifetime
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2398056A1 (fr) * | 1977-07-20 | 1979-02-16 | Merck Patent Gmbh | Thioethers basiques et leur procede de preparation |
EP0176049A2 (fr) * | 1984-09-28 | 1986-04-02 | Consiglio Nazionale Delle Ricerche | Dérivés de l'aminoalkylnaphtalène doués d'une activité pharmacologique |
EP0176049A3 (en) * | 1984-09-28 | 1987-06-03 | Consiglio Nazionale Delle Ricerche | Aminoalkylnaphtalene derivatives having pharmacological activities |
EP0539805A1 (fr) * | 1991-10-31 | 1993-05-05 | ASTA Medica Aktiengesellschaft | Phthalazines substituées en position 1 par un groupe éther ou thioéther et procédé pour leur préparation |
Also Published As
Publication number | Publication date |
---|---|
SE7511932L (sv) | 1976-04-27 |
IL48319A0 (en) | 1975-12-31 |
DD122680A5 (fr) | 1976-10-20 |
LU73641A1 (fr) | 1977-05-31 |
ES442058A1 (es) | 1977-07-01 |
ATA813575A (de) | 1978-06-15 |
CA1073907A (fr) | 1980-03-18 |
ES456348A1 (es) | 1978-06-16 |
JPS51125231A (en) | 1976-11-01 |
IE43071B1 (en) | 1980-12-17 |
ES456347A1 (es) | 1978-07-01 |
HU175263B (hu) | 1980-06-28 |
NL7512485A (nl) | 1976-04-28 |
ES456349A1 (es) | 1978-07-01 |
IE43071L (en) | 1976-04-26 |
AU8593775A (en) | 1977-04-28 |
US4239759A (en) | 1980-12-16 |
FR2288518B1 (fr) | 1980-05-30 |
AU497803B2 (en) | 1979-01-11 |
GB1476106A (en) | 1977-06-10 |
AT347928B (de) | 1979-01-25 |
DK479575A (da) | 1976-04-27 |
US4110447A (en) | 1978-08-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |