FR2285880A1 - Apovincaminic and desoxyvincaminic acid amides - of cycloalkyl amines for treatment of anoxic disorders - Google Patents

Apovincaminic and desoxyvincaminic acid amides - of cycloalkyl amines for treatment of anoxic disorders

Info

Publication number
FR2285880A1
FR2285880A1 FR7432095A FR7432095A FR2285880A1 FR 2285880 A1 FR2285880 A1 FR 2285880A1 FR 7432095 A FR7432095 A FR 7432095A FR 7432095 A FR7432095 A FR 7432095A FR 2285880 A1 FR2285880 A1 FR 2285880A1
Authority
FR
France
Prior art keywords
desoxyvincaminic
apovincaminic
treatment
acid amides
disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7432095A
Other languages
French (fr)
Other versions
FR2285880B1 (en
Inventor
Don Pierre Rene Luc Giudicelli
Henry Najer
Patrick Andre Louis Lardenois
Jean Pierre Gaston Lefevre
Bogdan Iliesco-Branceni
Icilio Angelo Girolamo Cavero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7432095A priority Critical patent/FR2285880A1/en
Priority to FI751840*A priority patent/FI751840A/fi
Priority to DK277975AA priority patent/DK138427B/en
Priority to SE7507088A priority patent/SE7507088L/en
Priority to NO752192A priority patent/NO752192L/no
Priority to ES75438799A priority patent/ES438799A1/en
Priority to IE1391/75A priority patent/IE41260B1/en
Priority to US05/589,088 priority patent/US4011330A/en
Priority to CH818075A priority patent/CH603651A5/xx
Priority to BE157636A priority patent/BE830587A/en
Priority to LU72792A priority patent/LU72792A1/xx
Priority to ZA00754071A priority patent/ZA754071B/en
Priority to CA230,244A priority patent/CA1031344A/en
Priority to DE2528609A priority patent/DE2528609C3/en
Priority to GB2736975A priority patent/GB1460235A/en
Priority to IL47590A priority patent/IL47590A/en
Priority to JP50079923A priority patent/JPS5139699A/en
Priority to AU82571/75A priority patent/AU491040B2/en
Priority to NL7508740A priority patent/NL7508740A/en
Publication of FR2285880A1 publication Critical patent/FR2285880A1/en
Application granted granted Critical
Publication of FR2285880B1 publication Critical patent/FR2285880B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Apovincaminic and desoxyvincaminic acid amides and their salts of formula (I) are new: (where either A and B = H and R = H or a group (II) or A and B together form a bond and R is a group (I)-(CH2)n- m = 1-4 and n = 0-3). I are used for treatment of disorders caused by anoxia, esp. of the central nervous system. I are prepd. from an apovincaminic or desoxyvincaminic acid halide by treatment with the amine RNH2. a nonpolar solvent opt. contg. an acid acceptor e.g. a tert org. base.
FR7432095A 1974-09-24 1974-09-24 Apovincaminic and desoxyvincaminic acid amides - of cycloalkyl amines for treatment of anoxic disorders Granted FR2285880A1 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
FR7432095A FR2285880A1 (en) 1974-09-24 1974-09-24 Apovincaminic and desoxyvincaminic acid amides - of cycloalkyl amines for treatment of anoxic disorders
FI751840*A FI751840A (en) 1974-09-24 1975-05-19
DK277975AA DK138427B (en) 1974-09-24 1975-06-19 Analogous process for the preparation of amides of apovincamine and deoxyvincamic acid or acid addition salts thereof.
SE7507088A SE7507088L (en) 1974-09-24 1975-06-19 APOVINKAMIN AND DESOXIVINKAMINIC ACID AMIDES
NO752192A NO752192L (en) 1974-09-24 1975-06-19
IE1391/75A IE41260B1 (en) 1974-09-24 1975-06-23 Vincaminic acid amides
US05/589,088 US4011330A (en) 1974-09-24 1975-06-23 Vincaminic acid amides
ES75438799A ES438799A1 (en) 1974-09-24 1975-06-23 Vincaminic acid amides
LU72792A LU72792A1 (en) 1974-09-24 1975-06-24
BE157636A BE830587A (en) 1974-09-24 1975-06-24 AMIDES OF APOVINCAMINIC AND DESOXYVINCAMINIC ACIDS
CH818075A CH603651A5 (en) 1974-09-24 1975-06-24
ZA00754071A ZA754071B (en) 1974-09-24 1975-06-25 Vincaminic acid amides
DE2528609A DE2528609C3 (en) 1974-09-24 1975-06-26 Deoxyvincamineamides, their salts with acids, process for their preparation and pharmaceuticals
CA230,244A CA1031344A (en) 1974-09-24 1975-06-26 Process for preparing vincaminic acid amines
GB2736975A GB1460235A (en) 1974-09-24 1975-06-27 Vincaminic acid amides
IL47590A IL47590A (en) 1974-09-24 1975-06-27 Desoxyvincaminic acid and apovincaminic acid amides,their preparation and pharmaceutical compositions containing them
JP50079923A JPS5139699A (en) 1974-09-24 1975-06-27 Abopinkaminsan oyobi deokishibinkaminsannoamidonoseiho
AU82571/75A AU491040B2 (en) 1975-06-30 Vincaminic acid amides
NL7508740A NL7508740A (en) 1974-09-24 1975-07-22 PROCESS FOR THE PREPARATION OF THE AMIDES OF APO-VINCAMIC ACID AND OF DESOXYVINCAMIC ACID AND PROCESS FOR THE PREPARATION OF PREPARATIONS CONTAINING THESE COMPOUNDS.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7432095A FR2285880A1 (en) 1974-09-24 1974-09-24 Apovincaminic and desoxyvincaminic acid amides - of cycloalkyl amines for treatment of anoxic disorders

Publications (2)

Publication Number Publication Date
FR2285880A1 true FR2285880A1 (en) 1976-04-23
FR2285880B1 FR2285880B1 (en) 1978-07-21

Family

ID=9143360

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7432095A Granted FR2285880A1 (en) 1974-09-24 1974-09-24 Apovincaminic and desoxyvincaminic acid amides - of cycloalkyl amines for treatment of anoxic disorders

Country Status (3)

Country Link
BE (1) BE830587A (en)
FR (1) FR2285880A1 (en)
ZA (1) ZA754071B (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2023918A1 (en) * 1968-11-22 1970-08-20 Richter Gedeon Vegyeszet
NL7307338A (en) * 1972-05-26 1973-11-28

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2023918A1 (en) * 1968-11-22 1970-08-20 Richter Gedeon Vegyeszet
NL7307338A (en) * 1972-05-26 1973-11-28

Also Published As

Publication number Publication date
ZA754071B (en) 1976-05-26
FR2285880B1 (en) 1978-07-21
BE830587A (en) 1975-12-24

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Legal Events

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