FR2285385A1 - Composes aromatiques bicycliques utiles dans la preparation des analogues de prostaglandines et leurs procede de preparation - Google Patents

Composes aromatiques bicycliques utiles dans la preparation des analogues de prostaglandines et leurs procede de preparation

Info

Publication number
FR2285385A1
FR2285385A1 FR7521890A FR7521890A FR2285385A1 FR 2285385 A1 FR2285385 A1 FR 2285385A1 FR 7521890 A FR7521890 A FR 7521890A FR 7521890 A FR7521890 A FR 7521890A FR 2285385 A1 FR2285385 A1 FR 2285385A1
Authority
FR
France
Prior art keywords
preparation
aromatic compounds
compounds useful
bicyclic aromatic
prostaglandin analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7521890A
Other languages
English (en)
French (fr)
Other versions
FR2285385B1 (cs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2285385A1 publication Critical patent/FR2285385A1/fr
Application granted granted Critical
Publication of FR2285385B1 publication Critical patent/FR2285385B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/27—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
FR7521890A 1974-07-12 1975-07-11 Composes aromatiques bicycliques utiles dans la preparation des analogues de prostaglandines et leurs procede de preparation Granted FR2285385A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48829574A 1974-07-12 1974-07-12
US55270775A 1975-02-24 1975-02-24

Publications (2)

Publication Number Publication Date
FR2285385A1 true FR2285385A1 (fr) 1976-04-16
FR2285385B1 FR2285385B1 (cs) 1979-03-09

Family

ID=27049301

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7521890A Granted FR2285385A1 (fr) 1974-07-12 1975-07-11 Composes aromatiques bicycliques utiles dans la preparation des analogues de prostaglandines et leurs procede de preparation
FR7539517A Granted FR2285373A1 (fr) 1974-07-12 1975-12-23 Preparation de bicyclo-carboxaldehydes utiles dans la synthese de prostaglandines
FR7539516A Granted FR2285364A1 (fr) 1974-07-12 1975-12-23 Preparation de bicyclo-acetals utiles dans la synthese de prostaglandines

Family Applications After (2)

Application Number Title Priority Date Filing Date
FR7539517A Granted FR2285373A1 (fr) 1974-07-12 1975-12-23 Preparation de bicyclo-carboxaldehydes utiles dans la synthese de prostaglandines
FR7539516A Granted FR2285364A1 (fr) 1974-07-12 1975-12-23 Preparation de bicyclo-acetals utiles dans la synthese de prostaglandines

Country Status (6)

Country Link
JP (1) JPS5134146A (cs)
CH (2) CH619922A5 (cs)
DE (1) DE2530221A1 (cs)
FR (3) FR2285385A1 (cs)
GB (3) GB1482047A (cs)
NL (1) NL7508301A (cs)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029681A (en) * 1976-02-13 1977-06-14 The Upjohn Company 13,14-Didehydro-PG analogs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SYNTHESIS, 1972, PAGES 261 - 262) *

Also Published As

Publication number Publication date
FR2285373A1 (fr) 1976-04-16
GB1482048A (en) 1977-08-03
FR2285364B1 (cs) 1980-07-18
FR2285385B1 (cs) 1979-03-09
JPS5134146A (ja) 1976-03-23
GB1482047A (en) 1977-08-03
CH615923A5 (en) 1980-02-29
AU8243775A (en) 1977-01-06
GB1482049A (en) 1977-08-03
DE2530221A1 (de) 1976-01-29
FR2285364A1 (fr) 1976-04-16
NL7508301A (nl) 1976-01-14
FR2285373B1 (cs) 1980-07-18
CH619922A5 (en) 1980-10-31

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Legal Events

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ST Notification of lapse