FR2282885A1 - Gastric secretion inhibitory pyrid-2-yl-thioureas - for prevention and treatment of peptic ulcers - Google Patents

Gastric secretion inhibitory pyrid-2-yl-thioureas - for prevention and treatment of peptic ulcers

Info

Publication number
FR2282885A1
FR2282885A1 FR7429610A FR7429610A FR2282885A1 FR 2282885 A1 FR2282885 A1 FR 2282885A1 FR 7429610 A FR7429610 A FR 7429610A FR 7429610 A FR7429610 A FR 7429610A FR 2282885 A1 FR2282885 A1 FR 2282885A1
Authority
FR
France
Prior art keywords
prevention
thioureas
pyrid
treatment
gastric secretion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7429610A
Other languages
French (fr)
Other versions
FR2282885B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to FR7429610A priority Critical patent/FR2282885A1/en
Publication of FR2282885A1 publication Critical patent/FR2282885A1/en
Application granted granted Critical
Publication of FR2282885B1 publication Critical patent/FR2282885B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Therapeutic compsns. comprising as active component a cpd. of formula (I): (where R1 is H, Me, R2 is H, Cl, Br, Me, R3 is H, Me, R4 is H, Cl, Br, Me, R5 is H, R7 or CO. R7, R7 is Me, Et, Pr, phenyl or benzyl, any of which may be substd. by OH, R6 is H Me, Et or R5 + R6 and the attached N-atom may form a 3-6 membered heterocyclic ring) or its acid addn. salt, are used for reduction of gastric secretion and prevention of peptic ulceration.
FR7429610A 1974-08-30 1974-08-30 Gastric secretion inhibitory pyrid-2-yl-thioureas - for prevention and treatment of peptic ulcers Granted FR2282885A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7429610A FR2282885A1 (en) 1974-08-30 1974-08-30 Gastric secretion inhibitory pyrid-2-yl-thioureas - for prevention and treatment of peptic ulcers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7429610A FR2282885A1 (en) 1974-08-30 1974-08-30 Gastric secretion inhibitory pyrid-2-yl-thioureas - for prevention and treatment of peptic ulcers

Publications (2)

Publication Number Publication Date
FR2282885A1 true FR2282885A1 (en) 1976-03-26
FR2282885B1 FR2282885B1 (en) 1978-07-21

Family

ID=9142681

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7429610A Granted FR2282885A1 (en) 1974-08-30 1974-08-30 Gastric secretion inhibitory pyrid-2-yl-thioureas - for prevention and treatment of peptic ulcers

Country Status (1)

Country Link
FR (1) FR2282885A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2059493A1 (en) * 1969-07-08 1971-06-04 Takeda Chemical Industries Ltd

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2059493A1 (en) * 1969-07-08 1971-06-04 Takeda Chemical Industries Ltd

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF PHARMACEUTICAL SCIENCES, VOL. 51, 1031-1033 1962 .) *

Also Published As

Publication number Publication date
FR2282885B1 (en) 1978-07-21

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Legal Events

Date Code Title Description
ST Notification of lapse