FR2281340A1 - Derives de l'acide folique, leur procede de preparation et leur application - Google Patents
Derives de l'acide folique, leur procede de preparation et leur applicationInfo
- Publication number
- FR2281340A1 FR2281340A1 FR7524796A FR7524796A FR2281340A1 FR 2281340 A1 FR2281340 A1 FR 2281340A1 FR 7524796 A FR7524796 A FR 7524796A FR 7524796 A FR7524796 A FR 7524796A FR 2281340 A1 FR2281340 A1 FR 2281340A1
- Authority
- FR
- France
- Prior art keywords
- derivatives
- application
- preparation process
- folic acid
- folic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical class C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/495,982 US3989812A (en) | 1974-08-09 | 1974-08-09 | Folic acid derivatives and use in radio-assay |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2281340A1 true FR2281340A1 (fr) | 1976-03-05 |
| FR2281340B1 FR2281340B1 (show.php) | 1977-12-16 |
Family
ID=23970770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7524796A Granted FR2281340A1 (fr) | 1974-08-09 | 1975-08-08 | Derives de l'acide folique, leur procede de preparation et leur application |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US3989812A (show.php) |
| JP (1) | JPS5143994A (show.php) |
| AR (1) | AR209314A1 (show.php) |
| BE (1) | BE831280A (show.php) |
| BR (1) | BR7505025A (show.php) |
| DE (1) | DE2535558A1 (show.php) |
| ES (1) | ES440028A1 (show.php) |
| FR (1) | FR2281340A1 (show.php) |
| GB (1) | GB1527871A (show.php) |
| PL (1) | PL99574B1 (show.php) |
| SE (1) | SE7508764L (show.php) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2455602A1 (fr) * | 1979-04-30 | 1980-11-28 | Union Carbide Corp | Derives d'acide folique marques au radio-iode, leur procede de production et leur application a l'analyse medicale |
| FR2460952A1 (fr) * | 1979-07-04 | 1981-01-30 | Daiichi Radioisotope Lab | Procede de determination radioimmunologique de pterines et nouveaux derives de pterine utiles dans ce procede |
| FR2510760A1 (fr) * | 1981-07-30 | 1983-02-04 | Corning Glass Works | Dosage de folates par fixation competitive de proteines perfectionne et jeu de reactifs pour sa mise en oeuvre |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1458978A (en) * | 1973-12-11 | 1976-12-22 | Radiochemical Centre Ltd | Saturation analysis |
| DE2631046A1 (de) * | 1975-07-15 | 1977-01-20 | Snam Progetti | Adeninderivate und verfahren zu deren herstellung |
| US4043759A (en) * | 1976-01-20 | 1977-08-23 | Charm Stanley E | Method of determining methotrexate |
| US4336185A (en) * | 1976-03-02 | 1982-06-22 | Rohm And Haas Company | Folic acid derivatives |
| US4276280A (en) * | 1976-09-29 | 1981-06-30 | Becton, Dickinson And Company | Radiolabeled derivatives of folic acid |
| US4202874A (en) * | 1976-09-29 | 1980-05-13 | Becton Dickinson & Company | Monoradioiodinated derivatives and precursors for production thereon |
| US4120867A (en) * | 1976-09-29 | 1978-10-17 | Becton, Dickinson & Company | Monoradioiodinated phenolic esters, acids and amines |
| US4136159A (en) * | 1977-02-28 | 1979-01-23 | New England Nuclear Corporation | Radioassay of folates |
| US4247453A (en) * | 1978-09-13 | 1981-01-27 | Abbott Laboratories | Folic acid derivatives for use in radioimmunoassay |
| IT1110926B (it) * | 1979-02-07 | 1986-01-13 | Innocenti Santeustacchio Spa | Metodo ed apparecchiatura per il controllo del movimento del mandrino in un laminatoio continuo a mandrino trattenuto |
| US4337339A (en) * | 1979-04-30 | 1982-06-29 | Baker Instruments Corp. | Process for preparation of folic acid derivatives |
| US4314988A (en) * | 1979-10-31 | 1982-02-09 | Baker Instruments Corp. | Folic acid derivatives and process for preparation |
| DE3262956D1 (en) * | 1981-06-22 | 1985-05-15 | Technicon Instr | Labelled vitamin b12 derivatives, their preparation and use |
| US5800979A (en) * | 1994-12-01 | 1998-09-01 | Kolhouse; J. Fred | Gas chromatography/mass spectrometric determination of folic acid coenzymes |
| US8173840B2 (en) * | 2003-07-29 | 2012-05-08 | Signature R&D Holdings, Llc | Compounds with high therapeutic index |
| US7589233B2 (en) * | 2003-07-29 | 2009-09-15 | Signature R&D Holdings, Llc | L-Threonine derivatives of high therapeutic index |
| KR101781461B1 (ko) | 2007-04-11 | 2017-10-23 | 메르크 앤드 씨에 | 18f-표지된 폴레이트의 제조방법 |
| RU2398774C2 (ru) * | 2008-11-13 | 2010-09-10 | Петербургский институт ядерной физики им. Б.П. Константинова РАН | Способ получения 3'-йодфолиевой и 3'-бромфолиевой кислот, меченных радиоактивными изотопами йода или брома |
| EP2921216A1 (en) | 2014-03-17 | 2015-09-23 | ETH Zurich | Heavy metal recycling process and material usefull in such process |
| CN118638025A (zh) | 2017-08-21 | 2024-09-13 | 细胞基因公司 | 制备(s)-4,5-二氨基-5-氧代戊酸叔丁酯的工艺 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3988431A (en) * | 1974-12-12 | 1976-10-26 | Becton, Dickinson And Company | Radioassay of folates |
-
1974
- 1974-08-09 US US05/495,982 patent/US3989812A/en not_active Expired - Lifetime
-
1975
- 1975-07-11 BE BE158218A patent/BE831280A/xx unknown
- 1975-08-04 SE SE7508764A patent/SE7508764L/xx unknown
- 1975-08-05 ES ES0440028A patent/ES440028A1/es not_active Expired
- 1975-08-06 BR BR7505025*A patent/BR7505025A/pt unknown
- 1975-08-07 AR AR259935A patent/AR209314A1/es active
- 1975-08-08 GB GB33145/75A patent/GB1527871A/en not_active Expired
- 1975-08-08 PL PL1975182634A patent/PL99574B1/pl unknown
- 1975-08-08 FR FR7524796A patent/FR2281340A1/fr active Granted
- 1975-08-08 DE DE19752535558 patent/DE2535558A1/de active Pending
- 1975-08-09 JP JP50097110A patent/JPS5143994A/ja active Pending
-
1976
- 1976-07-28 US US05/709,483 patent/US4091087A/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2455602A1 (fr) * | 1979-04-30 | 1980-11-28 | Union Carbide Corp | Derives d'acide folique marques au radio-iode, leur procede de production et leur application a l'analyse medicale |
| FR2460952A1 (fr) * | 1979-07-04 | 1981-01-30 | Daiichi Radioisotope Lab | Procede de determination radioimmunologique de pterines et nouveaux derives de pterine utiles dans ce procede |
| FR2510760A1 (fr) * | 1981-07-30 | 1983-02-04 | Corning Glass Works | Dosage de folates par fixation competitive de proteines perfectionne et jeu de reactifs pour sa mise en oeuvre |
Also Published As
| Publication number | Publication date |
|---|---|
| BE831280A (fr) | 1976-01-12 |
| FR2281340B1 (show.php) | 1977-12-16 |
| US4091087A (en) | 1978-05-23 |
| PL99574B1 (pl) | 1978-07-31 |
| GB1527871A (en) | 1978-10-11 |
| US3989812A (en) | 1976-11-02 |
| DE2535558A1 (de) | 1976-02-26 |
| BR7505025A (pt) | 1976-08-03 |
| SE7508764L (sv) | 1976-02-10 |
| AR209314A1 (es) | 1977-04-15 |
| AU8373975A (en) | 1977-02-10 |
| ES440028A1 (es) | 1977-09-16 |
| JPS5143994A (en) | 1976-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |