FR2280385A1 - Nouveaux n-(o-hexamethyleneiminoalkyl) 5h-dibenzo(b,f)-azepine carboxamides-5, utiles notamment comme agents antiarythmiques, et leur procede de preparation - Google Patents

Nouveaux n-(o-hexamethyleneiminoalkyl) 5h-dibenzo(b,f)-azepine carboxamides-5, utiles notamment comme agents antiarythmiques, et leur procede de preparation

Info

Publication number
FR2280385A1
FR2280385A1 FR7523526A FR7523526A FR2280385A1 FR 2280385 A1 FR2280385 A1 FR 2280385A1 FR 7523526 A FR7523526 A FR 7523526A FR 7523526 A FR7523526 A FR 7523526A FR 2280385 A1 FR2280385 A1 FR 2280385A1
Authority
FR
France
Prior art keywords
hexamethyleneiminoalkyl
dibenzo
useful
new
preparation process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7523526A
Other languages
English (en)
Other versions
FR2280385B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of FR2280385A1 publication Critical patent/FR2280385A1/fr
Application granted granted Critical
Publication of FR2280385B1 publication Critical patent/FR2280385B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
    • C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7523526A 1974-07-29 1975-07-28 Nouveaux n-(o-hexamethyleneiminoalkyl) 5h-dibenzo(b,f)-azepine carboxamides-5, utiles notamment comme agents antiarythmiques, et leur procede de preparation Granted FR2280385A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49245474A 1974-07-29 1974-07-29

Publications (2)

Publication Number Publication Date
FR2280385A1 true FR2280385A1 (fr) 1976-02-27
FR2280385B1 FR2280385B1 (fr) 1979-06-15

Family

ID=23956318

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7523526A Granted FR2280385A1 (fr) 1974-07-29 1975-07-28 Nouveaux n-(o-hexamethyleneiminoalkyl) 5h-dibenzo(b,f)-azepine carboxamides-5, utiles notamment comme agents antiarythmiques, et leur procede de preparation

Country Status (17)

Country Link
US (1) US4076707A (fr)
JP (1) JPS5136474A (fr)
AR (2) AR205239A1 (fr)
AU (1) AU8343775A (fr)
BE (1) BE831815A (fr)
DE (1) DE2533738A1 (fr)
DK (1) DK342075A (fr)
ES (1) ES439820A1 (fr)
FI (1) FI752157A (fr)
FR (1) FR2280385A1 (fr)
GB (1) GB1507395A (fr)
IE (1) IE41281B1 (fr)
IL (1) IL47805A0 (fr)
NL (1) NL7508972A (fr)
NO (1) NO752655L (fr)
SE (1) SE7508532L (fr)
ZA (1) ZA754828B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD152782B1 (de) * 1979-11-05 1988-11-30 Ernst Carstens Verfahren zur herstellung neuer 10.11-dihydro-5h-dibenz[b,f]azepine und ihrer salze

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1332146A (fr) * 1961-06-09 1963-12-16

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2666051A (en) * 1954-01-12 N-acyl derivatives of iminodibenzyl
US2965638A (en) * 1958-03-20 1960-12-20 Geigy Chem Corp Nu-substituted azepines and dihydroazepines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1332146A (fr) * 1961-06-09 1963-12-16

Also Published As

Publication number Publication date
AU8343775A (en) 1977-02-03
FI752157A (fr) 1976-01-30
ES439820A1 (es) 1977-04-16
ZA754828B (en) 1976-09-29
SE7508532L (sv) 1976-01-30
NL7508972A (nl) 1976-02-02
IE41281L (en) 1976-01-29
IE41281B1 (en) 1979-11-21
GB1507395A (en) 1978-04-12
AR204667A1 (es) 1976-02-20
JPS5136474A (en) 1976-03-27
AR205239A1 (es) 1976-04-12
BE831815A (fr) 1976-01-28
US4076707A (en) 1978-02-28
FR2280385B1 (fr) 1979-06-15
DK342075A (da) 1976-01-30
NO752655L (fr) 1976-01-30
DE2533738A1 (de) 1976-04-15
IL47805A0 (en) 1975-10-15

Similar Documents

Publication Publication Date Title
FR2294703A1 (fr) Nouvelles cyanoguanidylpyridines, utiles notamment comme hypotenseurs, et leur procede de preparation
FR2497203B1 (fr) Nouveaux 7-oxa-bicycloheptanes et -bicycloheptenes utiles notamment comme agents cardiovasculaires, et leur procede de preparation
BE748392A (fr) Nouvelles phenylpyrrolidines, utiles notamment comme decontractants musculaires et anticonvulsifs, et leur procede de preparation
FR2286134A1 (fr) Nouvelles urethannoxazolidines, et leur procede de preparation
FR2318152A1 (fr) Nouvelles n-(3-trifluoromethyl-4-halogeno-phenyl)-n'-benzoyl-urees, leur procede de preparation et leur application comme insecticides
FR2317934A1 (fr) Nouveaux 16-dehydro-androstanes, utiles notamment en dermatologie, et leur procede de preparation
FR2319343A1 (fr) Nouvelles guanidines, leur procede de preparation et leur application
LU80476A1 (fr) Nouvelles 4-quinolyl-guanidines,utiles notamment comme anti-inflammatoires,et leur procede de preparation
BE826851A (fr) Nouvelles alkoxycarbonylphenylurees, leur procede de preparation et leur application comme herbicides
BE843840A (fr) Nouvelles guanidines et thiourees, leur procede de preparation et leur utilisations
FR2277817A1 (fr) Nouveaux carbamates, leur procede de preparation et leur application comme insecticides et acaricides
FR2348920A1 (fr) Nouveaux triazapentadienes,leur procede de preparation et leur application comme acaricides
FR2319350A1 (fr) Nouveaux 3-aminoalcoxyphenyl-2, 3, 3a, 4-tetrahydro-indeno-, 2h-naphto- et benzocyclohepta(l,2-c)pyrazoles, utiles notamment comme antidepresseurs et leur procede de preparation
BE776644A (fr) Nouveaux n-(-n-(cyano-3 diphenyl-3,3 propyl) phenyl-4 piperidinecarbonyloxy-4 amides utiles notamment comme agents antidiarrheiques et leur procede de preparation
BE832364A (fr) 17 alpha-hydroxy-1,3,5(10), 15-oestratetraenes et leur procede de preparation
FR2320746A1 (fr) Nouveau thiopyranno(4,3-c)pyrasoles, utiles notamment comme anti-inflammatoires et leur procede de preparation
FR2280385A1 (fr) Nouveaux n-(o-hexamethyleneiminoalkyl) 5h-dibenzo(b,f)-azepine carboxamides-5, utiles notamment comme agents antiarythmiques, et leur procede de preparation
BE845384A (fr) Nouveaux 2-phenylimino-1,3-dithiolanes substitues, leur procede de preparation et leur application comme ectoparasiticides
BE815362A (fr) Nouveaux carbamates d'ergolines utiles notamment comme vasodilatateurs peripheriques et leur procede de preparation
FR2299300A1 (fr) Trihalogeno-1,1,1-methyl-4-pentene-3-ols-2 et leur procede de preparation
BE818923A (fr) N-(2,4-dihalogeno-s-triazin-6-yl)-urees et leur procede de preparation
FR2348217A1 (fr) Nouveaux bis-penicillanoyloxyalcanes utiles notamment comme antibiotiques et leur procede de preparation
BE839521A (fr) Nouveaux carbamates de 2-halogenoergolines et 2-halogenoergolenes, utiles notamment comme vasodilatateurs, et leur procede de preparation
BE835427A (fr) Nouveaux methylenesteroides, et leur procede de preparation
FR2308631A1 (fr) Nouveaux n-alcoyl et cycloalcoyl thioacrylamides, leur procede de preparation et leur application comme fongicides

Legal Events

Date Code Title Description
ST Notification of lapse