FR2279396A1 - N-Aminoalkyl-3-nitronaphthalimides - prepd. by reacting 3-nitro-naphthalic acid or its reactive deriv. with a 2-amino-ethylamine - Google Patents

N-Aminoalkyl-3-nitronaphthalimides - prepd. by reacting 3-nitro-naphthalic acid or its reactive deriv. with a 2-amino-ethylamine

Info

Publication number
FR2279396A1
FR2279396A1 FR7425928A FR7425928A FR2279396A1 FR 2279396 A1 FR2279396 A1 FR 2279396A1 FR 7425928 A FR7425928 A FR 7425928A FR 7425928 A FR7425928 A FR 7425928A FR 2279396 A1 FR2279396 A1 FR 2279396A1
Authority
FR
France
Prior art keywords
prepd
reacting
nitronaphthalimides
aminoalkyl
ethylamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7425928A
Other languages
French (fr)
Other versions
FR2279396B1 (en
Inventor
Cristobal Martinez Roldan
Miguel Fernandez Brana
Jose Maria Castellano Berlanga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Made SA
Original Assignee
Laboratorios Made SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Made SA filed Critical Laboratorios Made SA
Priority to FR7425928A priority Critical patent/FR2279396A1/en
Publication of FR2279396A1 publication Critical patent/FR2279396A1/en
Application granted granted Critical
Publication of FR2279396B1 publication Critical patent/FR2279396B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pharmacologically active cpds. of formula (I): (where Y is 2-dimethylaminoethyl, 2-diethylaminoethyl, 2-pyrrolidinoethyl or 2-piperidinoethyl), are prepd. by reacting 3-nitronaphthalic acid, a reactive deriv. thereof, or the anhydride thereof with H2N-Y in a suitable solvent and isolating the prodt. in a conventional manner.
FR7425928A 1974-07-25 1974-07-25 N-Aminoalkyl-3-nitronaphthalimides - prepd. by reacting 3-nitro-naphthalic acid or its reactive deriv. with a 2-amino-ethylamine Granted FR2279396A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7425928A FR2279396A1 (en) 1974-07-25 1974-07-25 N-Aminoalkyl-3-nitronaphthalimides - prepd. by reacting 3-nitro-naphthalic acid or its reactive deriv. with a 2-amino-ethylamine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7425928A FR2279396A1 (en) 1974-07-25 1974-07-25 N-Aminoalkyl-3-nitronaphthalimides - prepd. by reacting 3-nitro-naphthalic acid or its reactive deriv. with a 2-amino-ethylamine

Publications (2)

Publication Number Publication Date
FR2279396A1 true FR2279396A1 (en) 1976-02-20
FR2279396B1 FR2279396B1 (en) 1977-09-09

Family

ID=9141710

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7425928A Granted FR2279396A1 (en) 1974-07-25 1974-07-25 N-Aminoalkyl-3-nitronaphthalimides - prepd. by reacting 3-nitro-naphthalic acid or its reactive deriv. with a 2-amino-ethylamine

Country Status (1)

Country Link
FR (1) FR2279396A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2392978A2 (en) * 1977-06-04 1978-12-29 Made Labor Sa SUBSTITUTE NAPHTHALIMIDES FOR USE AS MEDICINAL PRODUCTS
EP1539150A1 (en) * 2002-07-08 2005-06-15 Chemgenex Pharmaceuticals Limited Naphthalimide synthesis including amonafide synthesis and pharmaceutical preparations thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2392978A2 (en) * 1977-06-04 1978-12-29 Made Labor Sa SUBSTITUTE NAPHTHALIMIDES FOR USE AS MEDICINAL PRODUCTS
EP1539150A1 (en) * 2002-07-08 2005-06-15 Chemgenex Pharmaceuticals Limited Naphthalimide synthesis including amonafide synthesis and pharmaceutical preparations thereof
EP1539150A4 (en) * 2002-07-08 2006-10-11 Chemgenex Pharmaceuticals Inc Naphthalimide synthesis including amonafide synthesis and pharmaceutical preparations thereof
EP2305257A1 (en) * 2002-07-08 2011-04-06 ChemGenex Pharmaceuticals, Inc. Amonafide salts and compositions comprising same

Also Published As

Publication number Publication date
FR2279396B1 (en) 1977-09-09

Similar Documents

Publication Publication Date Title
GB1415378A (en) Photopolymerisable compositions and elements
GB1528326A (en) Tents
ES424067A1 (en) Triazolobenzodiazepines
FR2279396A1 (en) N-Aminoalkyl-3-nitronaphthalimides - prepd. by reacting 3-nitro-naphthalic acid or its reactive deriv. with a 2-amino-ethylamine
GB1418371A (en) Ethylene/a-monoolefin/triene copolymeric elastomers
IE39873B1 (en) 1 3-oxygenated 8a-oestratrienes
GB1363472A (en) 17-chlorosteroids
BE827914A (en) PROCESS FOR THE PREPARATION OF SULPHURIC ANHYDRIDE FROM SULPHURIC ANHYDRIDE AND OXYGEN
ES445144A1 (en) Indolobenzazepine derivatives
ES441639A1 (en) Novel corticoids
GB1434378A (en) Cyano-pregnene compounds
FR2216288A1 (en) Cephalosporin acetoxymethyl esters - useful as antibacterials and cephalosporin inters
GB1464072A (en) Purification of hydroquinone
BE813368A (en) 3,5-Dimethylbenzamide derivs - with anti-inflammatory and anticonvulsant activity
CH571064A5 (en) Recovery of rieamycin from broths - by oxidn to an insol form
GB1312532A (en) Process for the esterification of 17-hydroxy steroids
FR2322867A1 (en) Ester prepn. from quinuclidinol - esterified with carboxylic anhydrides and opt. converted to hydrohalides
FR2209553A1 (en) Phosphorylated-cholines - as lipotropic, anti-steatosis antitoxic, choleretic and liver cell protecting agents
JPS5210257A (en) Preparation of benzofuran derivatives
ES408183A1 (en) Process of making penicillamine
FR2168245A1 (en) Dimethylamino ethanol pyridinecarboxylate - cholinergic and antiinflammatory
JPS5227792A (en) Synthesis of cephalosporin compounds
FR1605008A (en) 3-dialkylaminoalkoxy-indazoles - with antirheumatic activity by two-stage process from 3-hydroxyindazoles
FR2191890A1 (en) Ethyl vincaminate and its salts - cerebral oxygenator and vasoregulator, prepd from vincaminic acid and diazoethane
FR2059981A1 (en) 1 2-bis 41-pyrrolidinomethyl-11 31-dioxolanyl-21 ethane