FR2276037A1 - 9-thia- ou oxothia- et dioxothia-11,12-seco-prostaglandines - Google Patents

9-thia- ou oxothia- et dioxothia-11,12-seco-prostaglandines

Info

Publication number
FR2276037A1
FR2276037A1 FR7519087A FR7519087A FR2276037A1 FR 2276037 A1 FR2276037 A1 FR 2276037A1 FR 7519087 A FR7519087 A FR 7519087A FR 7519087 A FR7519087 A FR 7519087A FR 2276037 A1 FR2276037 A1 FR 2276037A1
Authority
FR
France
Prior art keywords
dioxothia
oxothia
prostaglandines
seco
thia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7519087A
Other languages
English (en)
French (fr)
Other versions
FR2276037B1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2276037A1 publication Critical patent/FR2276037A1/fr
Application granted granted Critical
Publication of FR2276037B1 publication Critical patent/FR2276037B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7519087A 1974-06-25 1975-06-18 9-thia- ou oxothia- et dioxothia-11,12-seco-prostaglandines Granted FR2276037A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48317874A 1974-06-25 1974-06-25
US56656675A 1975-04-09 1975-04-09

Publications (2)

Publication Number Publication Date
FR2276037A1 true FR2276037A1 (fr) 1976-01-23
FR2276037B1 FR2276037B1 (de) 1979-03-02

Family

ID=27047557

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7519087A Granted FR2276037A1 (fr) 1974-06-25 1975-06-18 9-thia- ou oxothia- et dioxothia-11,12-seco-prostaglandines

Country Status (16)

Country Link
JP (1) JPS51125020A (de)
CA (1) CA1064961A (de)
CH (1) CH614935A5 (de)
DE (1) DE2528070A1 (de)
DK (1) DK263775A (de)
ES (1) ES438765A1 (de)
FI (1) FI751730A (de)
FR (1) FR2276037A1 (de)
GB (1) GB1476262A (de)
IE (1) IE41258B1 (de)
IL (1) IL47487A (de)
LU (1) LU72797A1 (de)
NL (1) NL7507020A (de)
NO (1) NO142219C (de)
NZ (1) NZ177843A (de)
SE (1) SE7506804L (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010518108A (ja) * 2007-02-06 2010-05-27 ユニバーシティ オブ ルーイビル リサーチ ファウンデーション，インコーポレーテッド 治療化合物
AU2012225574A1 (en) 2011-03-07 2013-09-26 University Of Louisville Research Foundation, Inc. Predictive marker of DNMT1 inhibitor therapeutic efficacy and methods of using the marker
US9737493B2 (en) 2012-09-07 2017-08-22 University Of Louisville Research Foundation, Inc. Compositions and methods for modulating DNMT1 inhibitor activity

Also Published As

Publication number Publication date
SE7506804L (sv) 1975-12-29
AU8221675A (en) 1976-12-23
DE2528070A1 (de) 1976-01-08
CA1064961A (en) 1979-10-23
ES438765A1 (es) 1977-07-01
JPS51125020A (en) 1976-11-01
NO752091L (de) 1975-12-30
NO142219B (no) 1980-04-08
DK263775A (da) 1975-12-26
IE41258L (en) 1975-12-25
NO142219C (no) 1980-07-16
FR2276037B1 (de) 1979-03-02
IL47487A (en) 1979-05-31
IL47487A0 (en) 1975-08-31
CH614935A5 (en) 1979-12-28
NL7507020A (nl) 1975-12-30
FI751730A (de) 1975-12-26
NZ177843A (en) 1978-04-03
IE41258B1 (en) 1979-11-21
GB1476262A (en) 1977-06-10
LU72797A1 (de) 1976-04-13

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Legal Events

Date Code Title Description
ST Notification of lapse