DK263775A - Fremgangsmade til fremstilling af 9-thia-eller oxothia- og dioxothia-11,12-seco-prostaglandiner - Google Patents

Fremgangsmade til fremstilling af 9-thia-eller oxothia- og dioxothia-11,12-seco-prostaglandiner

Info

Publication number
DK263775A
DK263775A DK263775A DK263775A DK263775A DK 263775 A DK263775 A DK 263775A DK 263775 A DK263775 A DK 263775A DK 263775 A DK263775 A DK 263775A DK 263775 A DK263775 A DK 263775A
Authority
DK
Denmark
Prior art keywords
dioxothia
oxothia
seco
thia
prostaglandins
Prior art date
Application number
DK263775A
Other languages
Danish (da)
English (en)
Inventor
E J Cragoe
J B Bicking
R L Smith
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK263775A publication Critical patent/DK263775A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/16Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C317/18Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK263775A 1974-06-25 1975-06-11 Fremgangsmade til fremstilling af 9-thia-eller oxothia- og dioxothia-11,12-seco-prostaglandiner DK263775A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48317874A 1974-06-25 1974-06-25
US56656675A 1975-04-09 1975-04-09

Publications (1)

Publication Number Publication Date
DK263775A true DK263775A (da) 1975-12-26

Family

ID=27047557

Family Applications (1)

Application Number Title Priority Date Filing Date
DK263775A DK263775A (da) 1974-06-25 1975-06-11 Fremgangsmade til fremstilling af 9-thia-eller oxothia- og dioxothia-11,12-seco-prostaglandiner

Country Status (16)

Country Link
JP (1) JPS51125020A (de)
CA (1) CA1064961A (de)
CH (1) CH614935A5 (de)
DE (1) DE2528070A1 (de)
DK (1) DK263775A (de)
ES (1) ES438765A1 (de)
FI (1) FI751730A (de)
FR (1) FR2276037A1 (de)
GB (1) GB1476262A (de)
IE (1) IE41258B1 (de)
IL (1) IL47487A (de)
LU (1) LU72797A1 (de)
NL (1) NL7507020A (de)
NO (1) NO142219C (de)
NZ (1) NZ177843A (de)
SE (1) SE7506804L (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010518108A (ja) * 2007-02-06 2010-05-27 ユニバーシティ オブ ルーイビル リサーチ ファウンデーション,インコーポレーテッド 治療化合物
AU2012225574A1 (en) 2011-03-07 2013-09-26 University Of Louisville Research Foundation, Inc. Predictive marker of DNMT1 inhibitor therapeutic efficacy and methods of using the marker
US9737493B2 (en) 2012-09-07 2017-08-22 University Of Louisville Research Foundation, Inc. Compositions and methods for modulating DNMT1 inhibitor activity

Also Published As

Publication number Publication date
SE7506804L (sv) 1975-12-29
AU8221675A (en) 1976-12-23
DE2528070A1 (de) 1976-01-08
CA1064961A (en) 1979-10-23
ES438765A1 (es) 1977-07-01
JPS51125020A (en) 1976-11-01
NO752091L (de) 1975-12-30
NO142219B (no) 1980-04-08
IE41258L (en) 1975-12-25
NO142219C (no) 1980-07-16
FR2276037B1 (de) 1979-03-02
IL47487A (en) 1979-05-31
IL47487A0 (en) 1975-08-31
FR2276037A1 (fr) 1976-01-23
CH614935A5 (en) 1979-12-28
NL7507020A (nl) 1975-12-30
FI751730A (de) 1975-12-26
NZ177843A (en) 1978-04-03
IE41258B1 (en) 1979-11-21
GB1476262A (en) 1977-06-10
LU72797A1 (de) 1976-04-13

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