FR2272681A1 - 6-(di) methylamino substd. cyclodextrin derivs - hypolipaemics prepd. from cyclodextrin, alkaryl sulphonyl chloride and (di) methylamine - Google Patents
6-(di) methylamino substd. cyclodextrin derivs - hypolipaemics prepd. from cyclodextrin, alkaryl sulphonyl chloride and (di) methylamineInfo
- Publication number
- FR2272681A1 FR2272681A1 FR7418856A FR7418856A FR2272681A1 FR 2272681 A1 FR2272681 A1 FR 2272681A1 FR 7418856 A FR7418856 A FR 7418856A FR 7418856 A FR7418856 A FR 7418856A FR 2272681 A1 FR2272681 A1 FR 2272681A1
- Authority
- FR
- France
- Prior art keywords
- cyclodextrin
- hypolipaemics
- derivs
- prepd
- substd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
(A) Cyclodextrin derivs. of formula (I) and their pharm. tolerable acid addn. salts, (n = 6 or 7; R = CH3NH or (CH3)2N; R2 = mesitylsuphonyl or 2, 4, 6-triisopropylbenzenesulphonyl), are prepd. along with corresp. cpds. (I; R = NH2), by reacting corresp. cyclodextrin (-CH2R replaced by -CH2OH) with R2X (X = halo) in presence of an acid acceptor to give (I; R = OR2) then reacting with R3H(R3 = R, NH2 or N3) or its alkali metal salt at 30-100 degrees C. and, where R3 = N3, hydrogenating. (I), and unsubstd. amino cpds., are hypolipaemics esp. hypocholesterolaemics.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7418856A FR2272681A1 (en) | 1974-05-30 | 1974-05-30 | 6-(di) methylamino substd. cyclodextrin derivs - hypolipaemics prepd. from cyclodextrin, alkaryl sulphonyl chloride and (di) methylamine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7418856A FR2272681A1 (en) | 1974-05-30 | 1974-05-30 | 6-(di) methylamino substd. cyclodextrin derivs - hypolipaemics prepd. from cyclodextrin, alkaryl sulphonyl chloride and (di) methylamine |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2272681A1 true FR2272681A1 (en) | 1975-12-26 |
Family
ID=9139478
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7418856A Withdrawn FR2272681A1 (en) | 1974-05-30 | 1974-05-30 | 6-(di) methylamino substd. cyclodextrin derivs - hypolipaemics prepd. from cyclodextrin, alkaryl sulphonyl chloride and (di) methylamine |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2272681A1 (en) |
-
1974
- 1974-05-30 FR FR7418856A patent/FR2272681A1/en not_active Withdrawn
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |