ES404001A1 - Complexs of polyriboinosinic acid and polyribo-2-thiocytidylic acid - Google Patents

Complexs of polyriboinosinic acid and polyribo-2-thiocytidylic acid

Info

Publication number
ES404001A1
ES404001A1 ES404001A ES404001A ES404001A1 ES 404001 A1 ES404001 A1 ES 404001A1 ES 404001 A ES404001 A ES 404001A ES 404001 A ES404001 A ES 404001A ES 404001 A1 ES404001 A1 ES 404001A1
Authority
ES
Spain
Prior art keywords
acid
formula
integer
polyribo
complexs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES404001A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712130544 external-priority patent/DE2130544A1/en
Priority claimed from DE19722218057 external-priority patent/DE2218057A1/en
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES404001A1 publication Critical patent/ES404001A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Abstract

Procedure for obtaining two-component complexes, which are composed of a) polyyribinosinic acid of formula I **(See formula)** where R1 means **(See formula)** k is an integer between 1 and 3 and b represents an integer between 1 and 2000 and b) polyrribo-2-thiocytidilic acid of formula II **(See formula)** where R2 means **(See formula)** m is an integer from 1 to 3 and n represents an integer from 1 to 2000 or its metal or ammonium salts; characterized by mixing solutions, preferably aqueous solutions, with different ionic strengths, of the homopolynucleotides of formula I, or of formula II, or their metal or ammonium salts, or that one of the components is prepared in a solution of the other component. (Machine-translation by Google Translate, not legally binding)
ES404001A 1971-06-19 1972-06-17 Complexs of polyriboinosinic acid and polyribo-2-thiocytidylic acid Expired ES404001A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19712130544 DE2130544A1 (en) 1971-06-19 1971-06-19 Polyribo-inosinic and 2-thiocytidylic acid complexes - as anti (virals, bacterials, protozoals) inducing interferon formation, also
DE19722218057 DE2218057A1 (en) 1972-04-14 1972-04-14 Loom - having two-component resilient stop for arresting - picker after picking

Publications (1)

Publication Number Publication Date
ES404001A1 true ES404001A1 (en) 1975-11-16

Family

ID=25761303

Family Applications (1)

Application Number Title Priority Date Filing Date
ES404001A Expired ES404001A1 (en) 1971-06-19 1972-06-17 Complexs of polyriboinosinic acid and polyribo-2-thiocytidylic acid

Country Status (12)

Country Link
US (1) US3843629A (en)
AU (1) AU467984B2 (en)
BE (1) BE785012A (en)
CA (1) CA988082A (en)
CH (1) CH584719A5 (en)
DD (1) DD100718A5 (en)
ES (1) ES404001A1 (en)
FR (1) FR2143060B1 (en)
GB (1) GB1364987A (en)
IL (1) IL39649A (en)
NL (1) NL7207984A (en)
SE (2) SE385587B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024222A (en) * 1973-10-30 1977-05-17 The Johns Hopkins University Nucleic acid complexes
US3952097A (en) * 1974-09-27 1976-04-20 The United States Of America As Represented By The Department Of Health, Education And Welfare Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid
JPS62252798A (en) * 1986-01-06 1987-11-04 Nippon Shinyaku Co Ltd Nucleic acid derivative
EP0333832B1 (en) * 1987-09-22 1992-06-03 Temple University Artificial dna base pair analogues
US4882147A (en) * 1987-12-16 1989-11-21 The Research Foundation Of State University Of New York Novel polynucleotide analogs, methods for inhibiting nucleic acid polymerases and methods for inducing synthesis of interferon
WO2005102278A1 (en) * 2002-07-03 2005-11-03 Oncovir, Inc. Method for preparation of poly-iclc and uses thereof

Also Published As

Publication number Publication date
NL7207984A (en) 1972-12-21
IL39649A0 (en) 1972-08-30
US3843629A (en) 1974-10-22
FR2143060A1 (en) 1973-02-02
CH584719A5 (en) 1977-02-15
FR2143060B1 (en) 1975-06-20
AU467984B2 (en) 1973-12-20
AU4347272A (en) 1973-12-20
CA988082A (en) 1976-04-27
BE785012A (en) 1972-12-18
SE7415908L (en) 1974-12-18
IL39649A (en) 1975-12-31
DD100718A5 (en) 1973-10-05
SE385587B (en) 1976-07-12
GB1364987A (en) 1974-08-29

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