FR2263750A1 - N-phenyl-N-(2-aryl-6-methyl-pyrimidin-4-yl)amino acid derivs. - useful e.g. as analeptics, hypotensives, analgesics, etc. - Google Patents
N-phenyl-N-(2-aryl-6-methyl-pyrimidin-4-yl)amino acid derivs. - useful e.g. as analeptics, hypotensives, analgesics, etc.Info
- Publication number
- FR2263750A1 FR2263750A1 FR7408340A FR7408340A FR2263750A1 FR 2263750 A1 FR2263750 A1 FR 2263750A1 FR 7408340 A FR7408340 A FR 7408340A FR 7408340 A FR7408340 A FR 7408340A FR 2263750 A1 FR2263750 A1 FR 2263750A1
- Authority
- FR
- France
- Prior art keywords
- phenyl
- hypotensives
- analgesics
- aryl
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000001953 Hypotension Diseases 0.000 title abstract 2
- 239000002269 analeptic agent Substances 0.000 title abstract 2
- 230000003555 analeptic effect Effects 0.000 title abstract 2
- 229940035676 analgesics Drugs 0.000 title abstract 2
- 239000000730 antalgic agent Substances 0.000 title abstract 2
- 208000021822 hypotensive Diseases 0.000 title abstract 2
- 230000001077 hypotensive effect Effects 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- -1 N-phenyl amino Chemical group 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 241000700159 Rattus Species 0.000 abstract 1
- 230000003361 anti-bronchoconstrictory effect Effects 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229940065524 anticholinergics inhalants for obstructive airway diseases Drugs 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7408340A FR2263750A1 (en) | 1974-03-12 | 1974-03-12 | N-phenyl-N-(2-aryl-6-methyl-pyrimidin-4-yl)amino acid derivs. - useful e.g. as analeptics, hypotensives, analgesics, etc. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7408340A FR2263750A1 (en) | 1974-03-12 | 1974-03-12 | N-phenyl-N-(2-aryl-6-methyl-pyrimidin-4-yl)amino acid derivs. - useful e.g. as analeptics, hypotensives, analgesics, etc. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2263750A1 true FR2263750A1 (en) | 1975-10-10 |
| FR2263750B1 FR2263750B1 (enExample) | 1977-11-04 |
Family
ID=9136174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7408340A Granted FR2263750A1 (en) | 1974-03-12 | 1974-03-12 | N-phenyl-N-(2-aryl-6-methyl-pyrimidin-4-yl)amino acid derivs. - useful e.g. as analeptics, hypotensives, analgesics, etc. |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2263750A1 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996032383A1 (en) * | 1995-04-13 | 1996-10-17 | Dainippon Pharmaceutical Co., Ltd. | Acetamide derivatives, process for producing the same, and medicinal composition containing the same |
| EP1610774A4 (en) * | 2003-04-09 | 2008-07-16 | Exelixis Inc | TIE-2 MODULATORS AND METHODS OF USE |
| US7816529B2 (en) | 2003-07-02 | 2010-10-19 | Vertex Pharmaceuticals Incorporated | Pyrimidines useful as modulators of voltage-gated ion channels |
-
1974
- 1974-03-12 FR FR7408340A patent/FR2263750A1/fr active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996032383A1 (en) * | 1995-04-13 | 1996-10-17 | Dainippon Pharmaceutical Co., Ltd. | Acetamide derivatives, process for producing the same, and medicinal composition containing the same |
| CN1094929C (zh) * | 1995-04-13 | 2002-11-27 | 大日本制药株式会社 | 乙酰胺衍生物,其制备方法,及含该衍生物的药物组合物 |
| EP1610774A4 (en) * | 2003-04-09 | 2008-07-16 | Exelixis Inc | TIE-2 MODULATORS AND METHODS OF USE |
| US7816529B2 (en) | 2003-07-02 | 2010-10-19 | Vertex Pharmaceuticals Incorporated | Pyrimidines useful as modulators of voltage-gated ion channels |
| US8324220B2 (en) | 2003-07-02 | 2012-12-04 | Vertex Pharmaceuticals Incorporated | Pyrimidines useful as modulators of voltage-gated ion channels |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2263750B1 (enExample) | 1977-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |